{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:38:51Z","timestamp":1765726731071,"version":"3.48.0"},"reference-count":24,"publisher":"BMJ","issue":"8","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81500306"],"award-info":[{"award-number":["81500306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"CAMS Innovation Fund for Medical Sciences","award":["2016-12M-3-011"],"award-info":[{"award-number":["2016-12M-3-011"]}]},{"name":"CAMS Innovation Fund for Medical Sciences","award":["2016-I2M-4-003"],"award-info":[{"award-number":["2016-I2M-4-003"]}]},{"name":"CAMS Innovation Fund for Medical Sciences","award":["2017-12M-3-008"],"award-info":[{"award-number":["2017-12M-3-008"]}]},{"name":"Peking Union Medical College (PUMC) Youth Fund and the Fundamental Research Funds for the Central Universities"},{"name":"the National Key Research and Development Program of China","award":["2016YFC0901500"],"award-info":[{"award-number":["2016YFC0901500"]}]},{"name":"the National Key Research and Development Program of China","award":["2016YFC0901502"],"award-info":[{"award-number":["2016YFC0901502"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2019,7,12]]},"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the effect of different ranges of systolic blood pressure (SBP) on left ventricular (LV) geometry and diastolic function in Chinese population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Peking Union Medical College Hospital in Beijing, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>All inhabitants aged 35 years or older, living in five villages of Shunyi were invited. Exclusion criteria included individuals who declined participation, presence of moderate to severe valvular heart disease, persistent atrial fibrillation and suboptimal echocardiograms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>The baseline data of 1051 participants were analysed. The relationship between SBP and LV geometric and diastolic function assessed by echocardiography was analysed after adjusting for conventional cardiac risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The adjusted value of SBP was independently associated with LV hypertrophy (LVH) and LV diastolic dysfunction (LVDDF) (all p&lt;0.01). Setting individuals with SBP &lt;120\u2009mm Hg as the reference group (group 1), those with SBP between 120\u2009mm Hg and 140\u2009mm Hg (group 2) had higher risk odds of LVH and those with SBP \u2265140\u2009mm Hg (group 3) had higher risk odds of LVH and LVDDF (all p&lt;0.01). With the increase of SBP, LV mass index (LVMI) and E\/e\u2032 stepwise increased and e\u2032 stepwise decreased significantly from group 1 to 3 (all p&lt;0.05). In the whole population, SBP was independently correlated with LVMI, LVEDD, Left Atrial Volume Index, e\u2032, and E\/e\u2032 (all p&lt;0.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SBP was independently related to LVH and LVDDF, SBP between 120 and 140\u2009mm Hg was independently related to worse LV remodelling and diastolic function, these findings indicated the potential benefit of intensive SBP control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2018-028398","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T11:31:26Z","timestamp":1567510286000},"page":"e028398","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of different ranges of systolic blood pressure on left ventricular structure and diastolic function in a Chinese population: a cross-sectional population-based Shunyi study"],"prefix":"10.1136","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1532-0029","authenticated-orcid":false,"given":"Liu","family":"Yongtai","sequence":"first","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lai","family":"Jinzhi","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhou","family":"Lixin","sequence":"additional","affiliation":[{"name":"Neurology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhai","family":"Feifei","sequence":"additional","affiliation":[{"name":"Neurology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Dingding","sequence":"additional","affiliation":[{"name":"Central Research Laboratory, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhu","family":"Yanlin","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Wei","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-1443","authenticated-orcid":false,"given":"Bai","family":"Hua","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Hui","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhu","family":"Yicheng","sequence":"additional","affiliation":[{"name":"Neurology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui","family":"Liying","sequence":"additional","affiliation":[{"name":"Neurology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Zhengyu","sequence":"additional","affiliation":[{"name":"Radiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuyang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Cardiology, Peking Union Medical College Hospital, Dongcheng-qu, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,9,3]]},"reference":[{"key":"2025121407362502000_9.8.e028398.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11911-8"},{"key":"2025121407362502000_9.8.e028398.2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200304000-00013"},{"key":"2025121407362502000_9.8.e028398.3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm236"},{"key":"2025121407362502000_9.8.e028398.4","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.427"},{"key":"2025121407362502000_9.8.e028398.5","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1097\/HJH.0000000000001940","article-title":"2018 ESC\/ESH guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of cardiology and the European Society of hypertension: the task force for the management of arterial hypertension of the European Society of cardiology and the European Society of hypertension","volume":"36","author":"Williams","year":"2018","journal-title":"J Hypertens"},{"key":"2025121407362502000_9.8.e028398.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2015.05.002"},{"key":"2025121407362502000_9.8.e028398.7","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.062950"},{"key":"2025121407362502000_9.8.e028398.8","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328308da55"},{"key":"2025121407362502000_9.8.e028398.9","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/hr.2016.191","article-title":"The influence of prehypertension, controlled and uncontrolled hypertension on left ventricular diastolic function and structure in the general Korean population","volume":"40","author":"Jung","year":"2017","journal-title":"Hypertens Res"},{"key":"2025121407362502000_9.8.e028398.10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"2025121407362502000_9.8.e028398.11","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.201400"},{"key":"2025121407362502000_9.8.e028398.12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.1.308"},{"key":"2025121407362502000_9.8.e028398.13","first-page":"67","article-title":"2019 Chinese guideline for the management of hypertension in the elderly","volume":"16","author":"Hua","year":"2019","journal-title":"J Geriatr Cardiol"},{"key":"2025121407362502000_9.8.e028398.14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of echocardiography and the European association of cardiovascular imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"2025121407362502000_9.8.e028398.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2016.01.011"},{"key":"2025121407362502000_9.8.e028398.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(98)70068-9"},{"key":"2025121407362502000_9.8.e028398.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.07.004"},{"key":"2025121407362502000_9.8.e028398.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01460-6"},{"key":"2025121407362502000_9.8.e028398.19","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpv156"},{"key":"2025121407362502000_9.8.e028398.20","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jjcc.2017.06.008","article-title":"The optimal cut-off of blood pressure related to left ventricular diastolic dysfunction and remodeling in Asian diabetic patients","volume":"71","author":"Jung","year":"2018","journal-title":"J Cardiol"},{"key":"2025121407362502000_9.8.e028398.21","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/MBP.0000000000000248","article-title":"Left ventricular myocardial performance index in prehypertensive patients with normal coronary arteries","volume":"22","author":"Ya\u015far","year":"2017","journal-title":"Blood Press Monit"},{"key":"2025121407362502000_9.8.e028398.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.11.006"},{"key":"2025121407362502000_9.8.e028398.23","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028441"},{"key":"2025121407362502000_9.8.e028398.24","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-019431","article-title":"Are self-reported telemonitored blood pressure readings affected by end-digit preference: a prospective cohort study in Scotland","volume":"8","author":"Parker","year":"2018","journal-title":"BMJ Open"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2018-028398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:36:33Z","timestamp":1765726593000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2018-028398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":24,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2019,9,3]]},"published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1136\/bmjopen-2018-028398"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2018-028398","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2019,8]]}}}