{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T20:30:55Z","timestamp":1774470655436,"version":"3.50.1"},"reference-count":37,"publisher":"BMJ","issue":"11","funder":[{"name":"Foundation Teaching Hospital OLVG"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2019,10,3]]},"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>In patients after a transient ischaemic attack (TIA) or minor stroke, dysfunction is often underestimated by clinical measures due to invisible symptoms, including cognitive and emotional problems. Many of these patients need stroke care programme, but others do not. In this study, we aim to identify potential predictors of quality of life (QoL) in patients with TIA or minor stroke 1 year poststroke to be able to select which of these patients will need aftercare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective observational cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single-centre hospital in the Netherlands.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>120 patients, diagnosed with TIA or minor stroke and discharged without rehabilitation treatment, completed the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Primary and secondary outcome measures<\/jats:title>\n                    <jats:p>QoL (RAND-36), anxiety and depressive symptoms (Hospital Anxiety and Depression scale), the degree of disability or functional dependence after stroke (modified Rankin Scale (mRS)) and symptoms of anxiety and depression specific to stroke (SSADQ) were assessed at baseline (2\u20136 weeks poststroke) and compared with follow-up at 1 year poststroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Depression (B=\u22121.35, p&lt;0.001) and anxiety (B=\u22120.57, p=0.041) at baseline predicted a worse mental component of QoL after 1 year. Depression (B=\u22121.100, p&lt;0.001) at baseline, but also age (B=\u22120.261, p=0.002) and female sex (B=4.101, p=0.034) predicted a worse physical component of QoL after 1 year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>With the identification of these predictors, we might be able to select more efficiently and timely the patients with TIA or minor stroke who need stroke aftercare.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2019-029697","type":"journal-article","created":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T10:05:51Z","timestamp":1572689151000},"page":"e029697","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":18,"title":["Predictors of quality of life 1 year after minor stroke or TIA: a prospective single-centre cohort study"],"prefix":"10.1136","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0926-1445","authenticated-orcid":false,"given":"Ka-Hoo","family":"Lam","sequence":"first","affiliation":[{"name":"Department of Neurology, OLVG, Amsterdam, Noord-Holland, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0565-2983","authenticated-orcid":false,"given":"Emma","family":"Blom","sequence":"additional","affiliation":[{"name":"Department of Neurology, OLVG, Amsterdam, Noord-Holland, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0942-6206","authenticated-orcid":false,"given":"Vincent I H","family":"Kwa","sequence":"additional","affiliation":[{"name":"Department of Neurology, OLVG, Amsterdam, Noord-Holland, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,11,2]]},"reference":[{"key":"2025120617562640000_9.11.e029697.1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.677724"},{"key":"2025120617562640000_9.11.e029697.2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/STR.0000000000000098","article-title":"Guidelines for adult stroke rehabilitation and recovery","volume":"47","author":"Winstein","year":"2016","journal-title":"Stroke"},{"key":"2025120617562640000_9.11.e029697.3","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1474-4422(18)30499-X","article-title":"Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the global burden of disease study 2016","volume":"18","author":"Feigin","year":"2019","journal-title":"Lancet Neurol"},{"key":"2025120617562640000_9.11.e029697.4","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.572883"},{"key":"2025120617562640000_9.11.e029697.5","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.192218"},{"key":"2025120617562640000_9.11.e029697.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2006.04.001"},{"key":"2025120617562640000_9.11.e029697.7","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.4.740"},{"key":"2025120617562640000_9.11.e029697.8","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-002-0792-3"},{"key":"2025120617562640000_9.11.e029697.9","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1159\/000132203","article-title":"High satisfaction with an individualised stroke care programme after hospitalisation of patients with a TIA or minor stroke: a pilot study","volume":"25","author":"Arts","year":"2008","journal-title":"Cerebrovasc Dis"},{"key":"2025120617562640000_9.11.e029697.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-6712.2009.00705.x"},{"key":"2025120617562640000_9.11.e029697.11","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jstrokecerebrovasdis.2010.05.012","article-title":"Subtle problems in activities of daily living after a transient ischemic attack or an apparently fully recovered non-disabling stroke","volume":"21","author":"Verbraak","year":"2012","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"2025120617562640000_9.11.e029697.12","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31826d5f3a"},{"key":"2025120617562640000_9.11.e029697.13","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12469"},{"key":"2025120617562640000_9.11.e029697.14","doi-asserted-by":"crossref","unstructured":"Fryer CE , Luker JA , McDonnell MN , et al . 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