{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T19:51:19Z","timestamp":1766087479988,"version":"3.48.0"},"reference-count":22,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2019,9,19]]},"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The occurrence and mortality of vasospastic angina pectoris (VAP) is largely unknown in western countries. Our objective was to clarify the occurrence, gender-distribution and mortality of VAP in Finland using a population-based hospital registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We studied consecutive patients aged \u226518 years hospitalized with VAP as the primary cause of admission in Finland during 2004\u20132014. The data were collected from obligatory nationwide registries. During the study period 1762 admissions were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Majority of all VAP patients were male (59.7%) and mean age was 65.7\u00b112.0 years. Annual admission rate for VAP was 2.29\/100\u2009000 person-years. Men were in higher risk for VAP than women (admission rate 3.00\/100\u2009000 vs 1.68\/100\u2009000; RR 1.70; p&lt;0.0001). Gender difference was not modified by age. Likelihood of VAP was highest in population aged 70\u201384 years. Admission rate for VAP decreased notably during the study period. One-year all-cause mortality was 8.0% and 3-year mortality was 15.5% (cardiac mortality 11.1%). Mortality was associated with increasing age, comorbidity burden and lack of detected coronary artery obstruction, but was similar between genders and during the study period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Men have higher risk for vasospastic angina caused admissions. Likelihood of vasospastic angina admission was highest in aged population. The 3-year all-cause mortality was 15.5%. Mortality was associated with increasing age, comorbidities and non-obstructive VAP diagnosis but was similar between genders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2019-030768","type":"journal-article","created":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T07:46:36Z","timestamp":1572853596000},"page":"e030768","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Occurrence and mortality of vasospastic angina pectoris hospitalised patients in Finland: a population-based registry cohort study"],"prefix":"10.1136","volume":"9","author":[{"given":"Essi","family":"Pikkarainen","sequence":"first","affiliation":[{"name":"Heart Centre, P\u00e4ij\u00e4t-H\u00e4me Central Hospital, Lahti, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juuso","family":"Blomster","sequence":"additional","affiliation":[{"name":"Heart Centre, Turku University Hospital, Turku, 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