{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:15:30Z","timestamp":1790712930552,"version":"4.1.0"},"reference-count":16,"publisher":"BMJ","issue":"12","funder":[{"name":"Ministry of Research","award":["ANR-11-INBS-0002"],"award-info":[{"award-number":["ANR-11-INBS-0002"]}]},{"name":"Caisse nationale d\u2019assurance maladie","award":["Constances"],"award-info":[{"award-number":["Constances"]}]},{"DOI":"10.13039\/501100020320","name":"IReSP","doi-asserted-by":"crossref","award":["CapaciT project AAP2014"],"award-info":[{"award-number":["CapaciT project AAP2014"]}],"id":[{"id":"10.13039\/501100020320","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2019,9,23]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The knee is one of the major sites of musculoskeletal pain, yet few large-scale studies have evaluated the impact of knee disorders on physical limitations. Our objective was to describe this impact in a large-scale population study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included subjects of working age from the CONSTANCES cohort, from its inception. Four groups were distinguished according to their medical history: whether they had knee arthroplasty (KA), meniscus surgery, severe knee pain, or none of these. Outcomes assessed for physical limitations were self-reported limitations in the last 6 months due to health problems, limitation on carrying 5\u2009kg on 10\u2009m and a 3-metre length rapid gait speed test (for participants aged &gt;45). Associations between knee groups and patients\u2019 characteristics and physical limitations were analysed using logistic regression. Robust associations were deemed relevant if their ORs were higher than 2 and their p value lower than 0.0001.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 114\u2009949 individuals, 99\u2009052 (86.2%) were in the \u2018no pain and no surgery\u2019 group, 14\u2009740 (12.8%) were in the severe knee pain group, 1019 (0.89%) had meniscus surgery and 138 (0.12%) had KA. Severe knee pain and KA groups showed a similar profile (they were less at work, reported more deterioration in their health and had more limitations).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Almost 14% of the sample had knee disorders. Subjects reporting severe knee pain or who had KA reported more important physical limitations then subjects who reported neither severe knee pain nor knee surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2019-031549","type":"journal-article","created":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T05:35:46Z","timestamp":1576474546000},"page":"e031549","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of severe knee pain, meniscus surgery and knee arthroplasty on physical ability: an observational study of 114 949 adults in the CONSTANCES cohort"],"prefix":"10.1136","volume":"9","author":[{"given":"Remi","family":"Valter","sequence":"first","affiliation":[{"name":"Occupational Health Unit, Poincar\u00e9 University Hospital, AP-HP (Paris Hospital) UVSQ, Garches, \u00cele-de-France, France"},{"name":"UMS 011, UMR-S 1168, Versailles St-Quentin Univ \u2013 Paris Saclay Univ, Versailles, \u00cele-de-France, France"},{"name":"VIMA : Aging and chronic diseases. Epidemiological and public health approaches, U1168, Inserm, Villejuif, F-94807, \u00cele-de-France, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Godeau","sequence":"additional","affiliation":[{"name":"Occupational and Environmental Diseases Unit, AP-HP (Paris Hospital) H\u00f4pital Avicenne, University hospital Paris Seine-Saint-Denis, Bobigny, F-93009, \u00cele-de-France, France"},{"name":"Paris 13 University Sorbonne, Paris, \u00cele-de-France, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Leclerc","sequence":"additional","affiliation":[{"name":"UMS 011 Population-based Epidemiologic Cohorts Unit, Inserm, Villejuif, \u00cele-de-France, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6028-3186","authenticated-orcid":false,"given":"Alexis","family":"Descatha","sequence":"additional","affiliation":[{"name":"UMS 011, UMR-S 1168, Versailles St-Quentin Univ \u2013 Paris Saclay Univ, Versailles, \u00cele-de-France, France"},{"name":"VIMA : Aging and chronic diseases. Epidemiological and public health approaches, U1168, Inserm, Villejuif, F-94807, \u00cele-de-France, France"},{"name":"UMS 011 Population-based Epidemiologic Cohorts Unit, Inserm, Villejuif, \u00cele-de-France, France"},{"name":"Irset (Institut de recherche en sant\u00e9, environnement et travail) - UMR_S1085, Univ Angers, CHU Angers, Univ Rennes, Inserm, Angers, F-49000, Pays de la Loire, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1554-0021","authenticated-orcid":false,"given":"Marc","family":"Fadel","sequence":"additional","affiliation":[{"name":"Occupational Health Unit, Poincar\u00e9 University Hospital, AP-HP (Paris Hospital) UVSQ, Garches, \u00cele-de-France, France"},{"name":"UMS 011, UMR-S 1168, Versailles St-Quentin Univ \u2013 Paris Saclay Univ, Versailles, \u00cele-de-France, France"},{"name":"VIMA : Aging and chronic diseases. Epidemiological and public health approaches, U1168, Inserm, Villejuif, F-94807, \u00cele-de-France, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,12,15]]},"reference":[{"key":"2025121511222539000_9.12.e031549.1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204763"},{"key":"2025121511222539000_9.12.e031549.2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-11-201112060-00004"},{"key":"2025121511222539000_9.12.e031549.3","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1177\/0363546516667578","article-title":"Rehabilitation protocols after isolated meniscal repair: a systematic review","volume":"45","author":"O\u2019Donnell","year":"2017","journal-title":"Am J Sports Med"},{"key":"2025121511222539000_9.12.e031549.4","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.02714"},{"key":"2025121511222539000_9.12.e031549.5","first-page":"875","article-title":"Nonsurgical management of knee pain in adults","volume":"92","author":"Jones","year":"2015","journal-title":"Am Fam Physician"},{"key":"2025121511222539000_9.12.e031549.6","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s10654-015-0096-4","article-title":"The French CONSTANCES population-based cohort: design, inclusion and follow-up","volume":"30","author":"Zins","year":"2015","journal-title":"Eur J Epidemiol"},{"key":"2025121511222539000_9.12.e031549.7","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2474-13-109","article-title":"Prevention of musculoskeletal disorders in workers: classification and health surveillance \u2013 statements of the scientific Committee on musculoskeletal disorders of the International Commission on occupational health","volume":"13","author":"Hagberg","year":"2012","journal-title":"BMC Musculoskelet Disord"},{"key":"2025121511222539000_9.12.e031549.8","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1302\/0301-620X.98B7.37410","article-title":"The role for arthroscopic partial meniscectomy in knees with degenerative changes","volume":"98-B","author":"Lamplot","year":"2016","journal-title":"Bone Joint J"},{"key":"2025121511222539000_9.12.e031549.9","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.k1651","article-title":"Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants","volume":"361","author":"Celis-Morales","year":"2018","journal-title":"BMJ"},{"key":"2025121511222539000_9.12.e031549.10","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2016.6449"},{"key":"2025121511222539000_9.12.e031549.11","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1016\/j.arth.2016.04.015","article-title":"Preoperative pain and function: profiles of patients selected for total knee arthroplasty","volume":"31","author":"Nguyen","year":"2016","journal-title":"J Arthroplasty"},{"key":"2025121511222539000_9.12.e031549.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2009.08.010"},{"key":"2025121511222539000_9.12.e031549.13","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1007\/s00167-013-2750-2","article-title":"Pain after knee arthroplasty: an unresolved issue","volume":"22","author":"Grosu","year":"2014","journal-title":"Knee Surg Sports Traumatol Arthrosc Off J ESSKA"},{"key":"2025121511222539000_9.12.e031549.14","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2011-000435","article-title":"What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? 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