{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:13:21Z","timestamp":1790208801197,"version":"4.1.0"},"reference-count":61,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T00:00:00Z","timestamp":1606953600000},"content-version":"unspecified","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2020,10,28]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>People experiencing homelessness have a high prevalence and incidence of traumatic brain injury (TBI) due to violence. Little is known about the effectiveness of interventions to reduce TBI in this population. This study assessed the effect of Housing First (HF) on violence-related TBI in adults with experiences of homelessness and mental illness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Pragmatic randomised trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>381 participants in the Toronto site of the At Home\/Chez randomised trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>HF participants were provided with scattered-site housing using rent supplements and supports from assertive community treatment or intensive case management teams (n=218, 57.2%). Control participants had access to treatment as usual (TAU) in the community (n=163, 42.8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Primary outcomes were an incident physical violence-related TBI event and the number of physical violence-related TBI events during the follow-up period (January 2014 to March 2017). Interval-censored survival time regression and zero-inflated negative binomial regression were used to assess the effect of HF on primary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among study participants, 9.2% (n=35) had an incident physical violence-related TBI event, and the mean physical violence-related TBI events was 0.16 (SD \u00b10.6). Compared with TAU participants, HF participants did not have a significantly lower risk of an incident violence-related TBI event (adjusted HR : 0.58 (95% CI, 0.29 to 1.14)), but they had a significantly lower number of physical violence-related TBI events (unadjusted incidence rate ratio (IRR): 0.22 (95% CI, 0.06 to 0.78); adjusted IRR: 0.15 (95% CI, 0.05 to 0.48)).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HF may be a useful intervention to reduce the burden of TBI due to physical violence among homeless individuals with mental illness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"ISRCTN42520374\">ISRCTN42520374<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-038443","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T17:26:09Z","timestamp":1607102769000},"page":"e038443","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Effect of Housing First on violence-related traumatic brain injury in adults with experiences of homelessness and mental illness: findings from the At Home\/Chez Soi randomised trial, Toronto site"],"prefix":"10.1136","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1131-8439","authenticated-orcid":false,"given":"Cilia","family":"Mejia-Lancheros","sequence":"first","affiliation":[{"name":"MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St Michael's Hospital, Unity Health Toronto, Toronto, Ontario, 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Available: www.socialstyrelsen.dk\/housingfirsteurope"},{"key":"2025121223245532000_10.12.e038443.35","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2011-000323"},{"key":"2025121223245532000_10.12.e038443.36","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S2215-0366(19)30371-2","article-title":"Long-Term effects of rent supplements and mental health support services on housing and health outcomes of homeless adults with mental illness: extension study of the at Home\/Chez Soi randomised controlled trial","volume":"6","author":"Stergiopoulos","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"2025121223245532000_10.12.e038443.37","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1080\/19371918.2016.1230081","article-title":"Surviving violence in everyday life: a communicative approach to homelessness","volume":"32","author":"Hsieh","year":"2017","journal-title":"Soc Work Public Health"},{"key":"2025121223245532000_10.12.e038443.38","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.2147\/NDT.S68321","article-title":"Violent victimization of adult patients with severe mental illness: a systematic review","volume":"10","author":"Latalova","year":"2014","journal-title":"Neuropsychiatr Dis Treat"},{"key":"2025121223245532000_10.12.e038443.39","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1353\/hpu.2015.0010","article-title":"Characteristics of traumatic brain injuries sustained among Veterans seeking homeless services","volume":"26","author":"Barnes","year":"2015","journal-title":"J Health Care Poor Underserved"},{"key":"2025121223245532000_10.12.e038443.40","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20130046"},{"key":"2025121223245532000_10.12.e038443.41","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-12-787"},{"key":"2025121223245532000_10.12.e038443.42","first-page":"22","article-title":"The Mini-International neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59 Suppl 20","author":"Sheehan","year":"1998","journal-title":"J Clin Psychiatry"},{"key":"2025121223245532000_10.12.e038443.43","doi-asserted-by":"publisher","DOI":"10.1007\/BF02189063"},{"key":"2025121223245532000_10.12.e038443.44","unstructured":"Waldmann CA . Traumatic brain injury (TBI). In: O\u2019Connell J , ed. The health of homeless persons: a manual of communicable disease and common problems in shelters and on the streets. Boston, MA: Boston Health Care for the Homeless Program and and the National Health Care for the Homeless Council, 2004: 237\u201341."},{"key":"2025121223245532000_10.12.e038443.45","unstructured":"Sun J . The statistical analysis of Interval-censored failure time data. New York, NY: Springer, 2006."},{"key":"2025121223245532000_10.12.e038443.46","doi-asserted-by":"publisher","DOI":"10.1177\/0962280209105023"},{"key":"2025121223245532000_10.12.e038443.47","doi-asserted-by":"crossref","first-page":"484","DOI":"10.21037\/atm.2016.08.45","article-title":"Parametric regression model for survival data: Weibull regression model as an example","volume":"4","author":"Zhang","year":"2016","journal-title":"Ann Transl Med"},{"key":"2025121223245532000_10.12.e038443.48","unstructured":"StataCorp LLC . stintreg \u2014 Parametric models for interval-censored survival-time data. In: Survival analysis reference manual. College Station, Texas: Stata Press, 2019: 468."},{"key":"2025121223245532000_10.12.e038443.49","doi-asserted-by":"crossref","first-page":"518","DOI":"10.22237\/jmasm\/1493598600","article-title":"A comparison of different methods of zero-inflated data analysis and an application in health surveys","volume":"16","author":"Yang","year":"2017","journal-title":"J Mod App Stat Meth"},{"key":"2025121223245532000_10.12.e038443.50","unstructured":"StataCorp . Stata statistical software: release 16, 2019."},{"key":"2025121223245532000_10.12.e038443.51","unstructured":"Muggah R . Researching the urban dilemma: urbanization, poverty and violence. Ottawa, Canada, 2012. Available: http:\/\/www.iadb.org\/intal\/intalcdi\/PE\/2012\/12203.pdf"},{"key":"2025121223245532000_10.12.e038443.52","unstructured":"Apraxine P , Duquenne A , Fetta S , et al . Urban violence and humanitarian challenges: joint report. 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