{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:47:37Z","timestamp":1784810857075,"version":"3.55.0"},"reference-count":30,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"unspecified","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007875","name":"Tulane University","doi-asserted-by":"publisher","award":["Evelyn and John G. Phillips Distinguished Chair"],"award-info":[{"award-number":["Evelyn and John G. Phillips Distinguished Chair"]}],"id":[{"id":"10.13039\/100007875","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD086794"],"award-info":[{"award-number":["R01HD086794"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2021,1,5]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                      (Ct) is the most commonly reported sexually transmitted infection in the USA and causes important reproductive morbidity in women. The Centers for Disease Control and Prevention recommend routine screening of sexually active women under age 25 but not among men. Despite three decades of screening women, chlamydia prevalence in women remains high. Untested and untreated men can serve as a reservoir of infection in women, and male-screening based intervention can be an effective strategy to reduce infection in women. We assessed the impact of screening men on the Ct prevalence in women.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>We created an individual-based network model to simulate a realistic chlamydia epidemic on sexual contact networks for a synthetic population (n=5000). The model is calibrated to the ongoing routine screening among African American (AA) women in the USA and detailed a male-screening programme, Check It, that bundles best practices for Ct control. We used sensitivity analysis to quantify the relative importance of each intervention component.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Community-based venues in New Orleans, Louisiana, USA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Heterosexual AA men, aged 15 to 24, who had sex with women in the past 2\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>Venue-based screening, expedited index treatment, expedited partner treatment and rescreening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We estimate that by annually screening 7.5% of the AA male population in the age-range, the chlamydia prevalence would be reduced relatively by 8.1% (95% CI 5.9% to 10.4%) in AA women and 8.8% (95% CI 6.9% to 10.8%) in AA men. Each man screened could prevent 0.062 (95% CI 0.030 to 0.094) cases in men and 0.204 (95% CI 0.143 to 0.267) cases in women. The model suggested the importance of intervention components ranked from high to low as venue-based screening, expedited index treatment, expedited partner treatment and rescreening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings indicated that male-screening has the potential to substantially reduce the prevalence among women in high-prevalence communities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-040789","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T14:51:12Z","timestamp":1611327072000},"page":"e040789","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of screening young men for\n                    <i>Chlamydia trachomatis<\/i>\n                    on the rates among women: a network modelling study for high-prevalence communities"],"prefix":"10.1136","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8653-5975","authenticated-orcid":false,"given":"Zhuolin","family":"Qu","sequence":"first","affiliation":[{"name":"Department of Mathematics, Tulane University, New Orleans, Louisiana, USA"},{"name":"Department of Mathematics, The University of Texas at San Antonio, San Antonio, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Azizi","sequence":"additional","affiliation":[{"name":"Simon A Levin Mathematical Computational Modeling Science Center, Arizona State University, Tempe, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norine","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Tulane University, New Orleans, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan Clare","family":"Craig-Kuhn","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Tulane University, New Orleans, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Stoecker","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, Tulane University, New Orleans, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Mac","family":"Hyman","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Tulane University, New Orleans, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2038-9151","authenticated-orcid":false,"given":"Patricia J","family":"Kissinger","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Tulane University, New Orleans, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,1,22]]},"reference":[{"key":"2025121221542148000_11.1.e040789.1","unstructured":"Centers for Disease Control and Prevention . Sexually transmitted disease surveillance 2018. Atlanta US Dep Health Hum Serv 2019."},{"key":"2025121221542148000_11.1.e040789.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199605233342111"},{"key":"2025121221542148000_11.1.e040789.3","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32833a8844"},{"key":"2025121221542148000_11.1.e040789.4","unstructured":"Centers for Disease Control and Prevention . Male Chlamydia screening consultation, March 28 \u2013 29, 2006, meeting report. Atlanta, Georgia, 2007. 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