{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T20:12:26Z","timestamp":1765743146564,"version":"3.48.0"},"reference-count":33,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"unspecified","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2020,12,12]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Underscreening of HIV and syphilis in clinical settings is pervasive in resource-constrained settings. Heavy patient loads and competing health priorities in these settings inhibit provider\u2019s ability to meet screening coverage targets. The objective of this study was to examine determinants of provider-initiated HIV and syphilis testing uptake at sexually transmitted disease (STD) clinics in China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A cross-sectional study was performed between July 2016 and December 2016.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Seven STD clinics in Guangdong Province, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Heterosexual STD clinic patients met the inclusion criteria, regardless of their interest in receiving HIV or syphilis testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome measures<\/jats:title>\n                    <jats:p>The syphilis and HIV testing uptake determined by patient receipt of results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1943 individuals were recruited in this study. Among those participants, 60.6% (1177\/1943) and 74.3% (1443\/1943) conducted HIV testing and syphilis testing during the study, respectively, of whom, 2.2% (26\/1177) and 21.5% (310\/1443) were found to be HIV-positive and syphilis-positive, respectively. The most common reason for rejecting HIV and syphilis testing was a low self-perceived risk of HIV and syphilis infection. After adjusting for covariates, condom use in the last sexual act, consistent condom use in the last 6 months, having paid sex in the last 6 months and having received any kind of HIV\/STD-related knowledge during the last 12 years were positively associated with both HIV and syphilis testing uptake.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The low-level of HIV and syphilis testing uptake, alongside with the high-level of engagement in risky sexual behaviours among heterosexual STD clinic patients, warranted a more targeted and intensive behavioural interventions to promote HIV and syphilis testing in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-041503","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T12:02:38Z","timestamp":1609243358000},"page":"e041503","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Uptake of provider-initiated HIV and syphilis testing among heterosexual STD clinic patients in Guangdong, China: results from a cross-sectional study"],"prefix":"10.1136","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9334-3744","authenticated-orcid":false,"given":"Peizhen","family":"Zhao","sequence":"first","affiliation":[{"name":"STD Control Department, Dermatology Hospital, Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"STD Control Department, Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9026-707X","authenticated-orcid":false,"given":"Weiming","family":"Tang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital, Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"STD Control Department, Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, China"},{"name":"Project-China, University of North Carolina at Chapel Hill, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanhuan","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shujie","family":"Huang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital, Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"STD Control Department, Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heping","family":"Zheng","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital, Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"STD Control Department, Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Yang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital, Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"STD Control Department, Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8000-9969","authenticated-orcid":false,"given":"Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital, Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"STD Control Department, Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,12,29]]},"reference":[{"key":"2025121412114908000_10.12.e041503.1","unstructured":"UNAIDS . UNAIDS report on the global AIDS epidemic, 2010."},{"key":"2025121412114908000_10.12.e041503.2","unstructured":"China CDC . Update on the AIDS\/STD epidemic in China in December 2017,2018. Chin J AIDS STD;24:111."},{"key":"2025121412114908000_10.12.e041503.3","doi-asserted-by":"crossref","DOI":"10.2471\/BLT.17.200923","article-title":"Syphilis screening and treatment: integration with HIV services","volume":"95","author":"Taylor","year":"2017","journal-title":"Bull World Health Organ"},{"key":"2025121412114908000_10.12.e041503.4","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/tmi.12671","article-title":"Lost opportunities to identify and treat HIV-positive patients: results from a baseline assessment of provider-initiated HIV testing and counselling (PITC) in Malawi","volume":"21","author":"Ahmed","year":"2016","journal-title":"Trop Med Int Health"},{"key":"2025121412114908000_10.12.e041503.5","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1086\/651477","article-title":"Integrating HIV screening into routine health care in resource-limited settings","volume":"50 Suppl 3","author":"Bassett","year":"2010","journal-title":"Clin Infect Dis"},{"key":"2025121412114908000_10.12.e041503.6","first-page":"32","article-title":"Effect analysis of promoting HIV and syphilis testing in Jiangmen, Guangdong","volume":"22","author":"Hongcheng","year":"2016","journal-title":"Chinese Journal of AIDS & STD"},{"key":"2025121412114908000_10.12.e041503.7","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/S0140-6736(13)61198-8","article-title":"Outpatient workload in China","volume":"381","author":"Li","year":"2013","journal-title":"Lancet"},{"key":"2025121412114908000_10.12.e041503.8","first-page":"158","article-title":"Promoting HIV and syphilis testing among sexually transmitted disease clinic attendees in the pearl River delta region, Guangdong","volume":"13","author":"Hongcheng","year":"2018","journal-title":"Modern Prev Med"},{"key":"2025121412114908000_10.12.e041503.9","doi-asserted-by":"crossref","first-page":"e000010","DOI":"10.1136\/bmjgh-2015-000010","article-title":"Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades","volume":"1","author":"Levi","year":"2016","journal-title":"BMJ Glob Health"},{"key":"2025121412114908000_10.12.e041503.10","unstructured":"National Health Commission of the People\u2019s Republic of China . Chinese program for syphilis prevention and control(2010-2020), 2010"},{"key":"2025121412114908000_10.12.e041503.11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0067092","article-title":"The characteristics of heterosexual STD clinic attendees who practice oral sex in Zhejiang Province, China","volume":"8","author":"Ma","year":"2013","journal-title":"PLoS One"},{"key":"2025121412114908000_10.12.e041503.12","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-13-44","article-title":"Hiv antibody testing and its correlates among heterosexual attendees of sexually transmitted disease clinics in China","volume":"13","author":"Ma","year":"2013","journal-title":"BMC Public Health"},{"key":"2025121412114908000_10.12.e041503.13","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-11-955","article-title":"HIV\/STD pattern and its associated risk factors among male STD clinic attendees in China: a foci for HIV intervention","volume":"11","author":"Wang","year":"2011","journal-title":"BMC Public Health"},{"key":"2025121412114908000_10.12.e041503.14","unstructured":"Prevention CDC . Sexually transmitted disease surveillance, 2018."},{"key":"2025121412114908000_10.12.e041503.15","unstructured":"National Health Commission of the People\u2019s Republic of China . Overview of the National statutory infectious diseases in 2018, 2019. Available: http:\/\/www.nhc.gov.cn\/jkj\/s3578\/201904\/050427ff32704a5db64f4ae1f6d57c6c.shtml"},{"key":"2025121412114908000_10.12.e041503.16","doi-asserted-by":"crossref","unstructured":"Wong NS , Huang S , Zheng H , et al . Stages of syphilis in South China \u2013 a multilevel analysis of early diagnosis. BMC Public Health 2017;17.doi:10.1186\/s12889-016-4004-y","DOI":"10.1186\/s12889-016-4004-y"},{"key":"2025121412114908000_10.12.e041503.17","unstructured":"Guangdong Bureau of Statistics . Guangdong Province yearly statistical data, 2020. Available: http:\/\/stats.gd.gov.cn\/"},{"key":"2025121412114908000_10.12.e041503.18","unstructured":"World Health Organisation . Provider-initiated HIV testing and counselling in health facilities, 2007."},{"key":"2025121412114908000_10.12.e041503.19","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.06.035188"},{"key":"2025121412114908000_10.12.e041503.20","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e318047df88"},{"key":"2025121412114908000_10.12.e041503.21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003501"},{"key":"2025121412114908000_10.12.e041503.22","first-page":"1","article-title":"Testing for HIV\/STIs in China: challenges, opportunities, and innovations","volume":"2017","author":"Zou","year":"2017","journal-title":"Biomed Res Int"},{"key":"2025121412114908000_10.12.e041503.23","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-017-2546-y","article-title":"Msm HIV testing following an online testing intervention in China","volume":"17","author":"Wong","year":"2017","journal-title":"BMC Infect Dis"},{"key":"2025121412114908000_10.12.e041503.24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0204489","article-title":"Hiv test uptake and related factors amongst heterosexual drug users in Shandong Province, China","volume":"13","author":"Jiang","year":"2018","journal-title":"PLoS One"},{"key":"2025121412114908000_10.12.e041503.25","doi-asserted-by":"crossref","DOI":"10.2196\/jmir.5692","article-title":"Can mobile phone Apps influence people's health behavior change? an evidence review","volume":"18","author":"Zhao","year":"2016","journal-title":"J Med Internet Res"},{"key":"2025121412114908000_10.12.e041503.26","doi-asserted-by":"publisher","DOI":"10.1080\/09540120903254005"},{"key":"2025121412114908000_10.12.e041503.27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0126659","article-title":"Expenditure analysis of HIV testing and counseling services using the cascade framework in Vietnam","volume":"10","author":"Nguyen","year":"2015","journal-title":"PLoS One"},{"key":"2025121412114908000_10.12.e041503.28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0067092","article-title":"The characteristics of heterosexual STD clinic attendees who practice oral sex in Zhejiang Province, China","volume":"8","author":"Ma","year":"2013","journal-title":"PLoS One"},{"key":"2025121412114908000_10.12.e041503.29","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-016-3590-z","article-title":"Condom use and incarceration among STI clinic attendees in the deep South","volume":"16","author":"Brinkley-Rubinstein","year":"2016","journal-title":"BMC Public Health"},{"key":"2025121412114908000_10.12.e041503.30","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2009.009019"},{"key":"2025121412114908000_10.12.e041503.31","doi-asserted-by":"crossref","DOI":"10.7448\/IAS.17.1.18573","article-title":"Condom use and HIV testing among men who have sex with men in Jordan","volume":"17","author":"Alkaiyat","year":"2014","journal-title":"J Int AIDS Soc"},{"key":"2025121412114908000_10.12.e041503.32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00038-013-0467-0","article-title":"Systematic review of HIV prevention interventions in China: a health communication perspective","volume":"59","author":"Xiao","year":"2014","journal-title":"Int J Public Health"},{"key":"2025121412114908000_10.12.e041503.33","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2015-052173"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2020-041503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T20:12:03Z","timestamp":1765743123000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2020-041503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":33,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12,29]]},"published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1136\/bmjopen-2020-041503"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2020-041503","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}