{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T09:07:14Z","timestamp":1765703234757,"version":"3.48.0"},"reference-count":28,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"unspecified","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001593","name":"Irish Cancer Society","doi-asserted-by":"publisher","award":["CNRA19HAN"],"award-info":[{"award-number":["CNRA19HAN"]}],"id":[{"id":"10.13039\/501100001593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2021,4,15]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Women who inherit a pathogenic mutation in Breast Cancer Susceptibility Genes 1 or 2 (BRCA1 or BRCA2) are at substantially higher risk of developing breast and ovarian cancer than the average woman. Several cancer risk management strategies exist to address this increased risk. Decisions about which risk management strategies to choose are complex, personal and multifactorial for these women. This scoping review will map evidence relevant to cancer risk management decision making in BRCA mutation carriers without a personal history of cancer. The objective is to identify and describe the features of patient decision aids that have been developed for BRCA mutation carriers. This information may be beneficial for designing new decision aids or adapting existing decision aids to support decision making in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This scoping review will be conducted according to the Joanna Briggs Institute\u2019s scoping review methodological framework. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist will be used for guidance. Studies on decision aids for women with a BRCA mutation who are unaffected by breast or ovarian cancer will be considered for inclusion. Five electronic databases will be searched (MEDLINE, EMBASE, Cochrane Library, CINAHL, Web of Science) with no restrictions applied for language or publication date. Studies for inclusion will be selected independently by two review authors. Data will be extracted using a predefined data extraction form. Findings will be presented in tabular form. A narrative description of the evidence will complement the tabulated results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethical approval for conducting this scoping review is not required as this study will involve secondary analysis of existing literature. Findings will be published in a peer-reviewed journal and presented at relevant conferences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-045075","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T12:38:12Z","timestamp":1626093492000},"page":"e045075","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Decision aids for female BRCA mutation carriers: a scoping review protocol"],"prefix":"10.1136","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4404-6564","authenticated-orcid":false,"given":"Sarah A","family":"McGarrigle","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geraldine","family":"Prizeman","sequence":"additional","affiliation":[{"name":"Trinity Centre for Practice and Healthcare Innovation, School of Nursing & Midwifery, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Spillane","sequence":"additional","affiliation":[{"name":"Breast Care Department, St. James\"s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niamh","family":"Byrne","sequence":"additional","affiliation":[{"name":"Breast Care Department, St. James\"s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1720-5673","authenticated-orcid":false,"given":"Amanda","family":"Drury","sequence":"additional","affiliation":[{"name":"School of Nursing, Midwifery and Health Systems, University College Dublin, Dublin, Ireland"},{"name":"School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mockler","sequence":"additional","affiliation":[{"name":"John Stearne Library, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M","family":"Connolly","sequence":"additional","affiliation":[{"name":"Breast Care Department, St. James\"s Hospital, Dublin, Ireland"},{"name":"Department of Surgery, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Marie","family":"Brady","sequence":"additional","affiliation":[{"name":"Trinity Centre for Practice and Healthcare Innovation, School of Nursing & Midwifery, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne P","family":"Hanhauser","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"key":"2025121401043258000_11.7.e045075.1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.7112"},{"key":"2025121401043258000_11.7.e045075.2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.6772"},{"key":"2025121401043258000_11.7.e045075.3","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-4436"},{"key":"2025121401043258000_11.7.e045075.4","doi-asserted-by":"crossref","DOI":"10.1093\/jncics\/pkaa029","article-title":"Penetrance of Breast and Ovarian Cancer in Women Who Carry a BRCA1\/2 Mutation and Do Not Use Risk-Reducing Salpingo-Oophorectomy: An Updated Meta-Analysis","volume":"4","author":"Chen","year":"2020","journal-title":"JNCI Cancer 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National Institute for Health and Care Excellence (NICE) (2013).Familial breast cancer: classification, care and managing breast cancer and related risks in people with a family history of breast cancer. Clinical guideline [CG164], 2013."},{"key":"2025121401043258000_11.7.e045075.19","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022698112236"},{"key":"2025121401043258000_11.7.e045075.20","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-011-9350-4"},{"key":"2025121401043258000_11.7.e045075.21","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.6060"},{"key":"2025121401043258000_11.7.e045075.22","doi-asserted-by":"crossref","DOI":"10.2196\/cancer.9210","article-title":"Development of a web-based family intervention for BRCA carriers and their biological relatives: acceptability, feasibility, and usability study","volume":"4","author":"Katapodi","year":"2018","journal-title":"JMIR Cancer"},{"key":"2025121401043258000_11.7.e045075.23","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s13187-019-1470-9","article-title":"Development and testing of a decision aid for unaffected women with a BRCA1 or BRCA2 mutation","volume":"35","author":"Jabaley","year":"2020","journal-title":"J Cancer Educ"},{"key":"2025121401043258000_11.7.e045075.24","first-page":"961","article-title":"An Applied Framework in Support of Shared Decision Making about BRCA Genetic Testing","volume":"2018","author":"Silverman","year":"2018","journal-title":"AMIA Annu Symp Proc"},{"key":"2025121401043258000_11.7.e045075.25","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-019-0872-2"},{"key":"2025121401043258000_11.7.e045075.26","doi-asserted-by":"crossref","unstructured":"Peters MDJ , Godfrey CM , McInerney P . Chapter 11: Scoping Reviews. In: Aromataris E , Munn Z , eds. 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