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The mean knowledge score was 11.86\/24 (SD 4.84). But over 70% of them held a positive attitude towards screening. Only 13.3% had undergone colorectal cancer screening. Independent factors related to knowledge were education level of college or above, working as a white collar, higher income, having health insurance, having seen a doctor in the past year and with a high perceived risk (p&lt;0.05). Factors independently associated with screening behaviour included personal history of colorectal disease, having seen a doctor in the past year, previous discussion of colorectal cancer screening, high perceived risk and better knowledge (p&lt;0.05). Main reasons for not undergoing screening were no symptoms or discomfort (71.1%), never having thought of the disease or screening (67.4%) and no doctor advised me (29.8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In China, the majority of high-risk people had deficient knowledge and had never undergone colorectal cancer screening. But most of them held a positive attitude towards the benefits of colorectal cancer screening. This has promising implications to design targeted educational campaigns and establish screening programmes to improve colorectal cancer awareness and screening participation. Healthcare professionals should advise high-risk individuals to participate in screening and inform them about cancer risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-045168","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T12:37:53Z","timestamp":1626093473000},"page":"e045168","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":34,"title":["Awareness, attitude and barriers of colorectal cancer screening among high-risk populations in China: a cross-sectional study"],"prefix":"10.1136","volume":"11","author":[{"given":"Ruo-lin","family":"Huang","sequence":"first","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"},{"name":"School of Nursing, The Hong Kong Polytechnic University, Kowloon, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-xin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-yu","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-feng","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-hui","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-zhuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zeng","sequence":"additional","affiliation":[{"name":"Hengyang No.8 High School, Hengyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Zeng","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Hunan Province Key Laboratory of Tumor Cellular & Molecular Pathology, University of South China, Hengyang, Hunan, China"},{"name":"Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2795-4616","authenticated-orcid":false,"given":"Ying","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of International and Humanistic Nursing, School of Nursing, University of South China, Hengyang, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"key":"2025120519032068000_11.7.e045168.1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"2025120519032068000_11.7.e045168.2","unstructured":"Cancer today. 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