{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:08:31Z","timestamp":1783098511702,"version":"3.54.6"},"reference-count":104,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T00:00:00Z","timestamp":1627516800000},"content-version":"unspecified","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"McMaster GRADE and Michael G DeGroote Cochrane Centres","award":["no specific award\/grant number"],"award-info":[{"award-number":["no specific award\/grant number"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2021,6,14]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Guidelines that include antimicrobial recommendations should explicitly consider contextual factors that influence antimicrobial resistance and their downstream effects on resistance selection. The objectives were to analyse (1) how, and to what extent, tuberculosis, gonorrhoea and respiratory tract infection guidelines are considering antimicrobial resistance; (2) are of acceptable quality and (3) if they can be easily contextualised to fit the needs of specific populations and health systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic review and searched Ovid MEDLINE and Embase from 1 January 2007 to 7 June 2019 for tuberculosis, gonorrhoea and respiratory tract infection guidelines published in English. We also searched guideline databases, key websites and reference lists. We identified guidelines and recommendations that considered contextual factors including antimicrobial resistance, values, resource use, equity, acceptability and feasibility. We assessed quality of the guidelines using the Appraisal of Guidelines for Research and Evaluation II tool focusing on the domains scope and purpose, rigour of development, and editorial independence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We screened 10\u2009365 records, of which 74 guidelines met inclusion criteria. Of these guidelines, 39% (n=29\/74) met acceptable quality scores. Approximately two-thirds of recommendations considered antimicrobial resistance at the population and\/or outcome level. Five of the 29 guidelines reported all factors required for recommendation contextualisation. Equity was the least considered across guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Relatively few guidelines for highly prevalent infectious diseases are considering resistance at a local level, and many do not consider contextual factors necessary for appropriate antimicrobial use. Improving the quality of guidelines targeting specific regional areas is required.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42020145235.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-046097","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T10:38:39Z","timestamp":1627641519000},"page":"e046097","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Consideration of antimicrobial resistance and contextual factors in infectious disease guidelines: a systematic survey"],"prefix":"10.1136","volume":"11","author":[{"given":"Rosa","family":"Stalteri Mastrangelo","sequence":"first","affiliation":[{"name":"Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada"},{"name":"Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Santesso","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada"},{"name":"Michael G. 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GuiaSalud 2010."},{"key":"2025121401192174000_11.7.e046097.69","unstructured":"National Institute for Health and Clinical Excellence - Clinical Guidelines . Sinusitis (acute): antimicrobial prescribing, 2017."},{"key":"2025121401192174000_11.7.e046097.70","unstructured":"British Association for Sexual Health and HIV . British association for sexual health and HIV national guideline for the management of infection with Neisseria gonorrhoeae, 2019."},{"key":"2025121401192174000_11.7.e046097.71","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.medmal.2017.01.005","article-title":"Guidelines on the management of infectious encephalitis in adults","volume":"47","author":"Stahl","year":"2017","journal-title":"Med Mal Infect"},{"key":"2025121401192174000_11.7.e046097.72","doi-asserted-by":"crossref","unstructured":"Heidemann CL J , Berg J , Christensen JJ , et al . 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Prevention, diagnosis and management of tuberculosis, 2016."},{"key":"2025121401192174000_11.7.e046097.85","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/1120009X.2007.11782432","article-title":"Management and prevention strategies for community-acquired pneumonia in the Gulf Corporation Council","volume":"19 Suppl 1","author":"Memish","year":"2007","journal-title":"J Chemother"},{"key":"2025121401192174000_11.7.e046097.86","first-page":"574-601","article-title":"Brazilian guidelines for community-acquired pneumonia in immunocompetent adults - 2009","volume":"35","author":"Corr\u00eaa","year":"2009","journal-title":"J Bras Pneumol"},{"key":"2025121401192174000_11.7.e046097.87","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.05.31"},{"key":"2025121401192174000_11.7.e046097.88","unstructured":"Chaves NJ PG , Biggs BA , Thambiran A . on behalf of the Australasian Society for Infectious Diseases and Refugee Health Network of Australia Guidelines writing group. In: Recommendations for comprehensive post-arrival health assessment for people from refugee-like backgrounds Australasian Society for infectious diseases and refugee health network of Australia. 2 edn, 2010."},{"key":"2025121401192174000_11.7.e046097.89","unstructured":"World Health Organisation Guidelines . WHO guidelines for the treatment of Neisseria gonorrhoeae, 2016."},{"key":"2025121401192174000_11.7.e046097.90","unstructured":"Anonymous. World Health Organization . WHO consolidated guidelines on drug-resistant tuberculosis treatment, 2019."},{"key":"2025121401192174000_11.7.e046097.91","unstructured":"World Health Organization . Improving the diagnosis and treatment of smear-negative pulmonary and extrapulmonary tuberculosis among adults and adolescents. recommendations for HIV-prevalent and resource-constrained settings, 2007."},{"key":"2025121401192174000_11.7.e046097.92","unstructured":"World Health Organization 2nd WHO Guidelines Approved by the Guidelines Review Committee . Guidance for national tuberculosis programmes on the management of tuberculosis in children, 2014."},{"key":"2025121401192174000_11.7.e046097.93","unstructured":"World Health Organisation Guidelines . Guidelines on the management of latent tuberculosis infection, 2015."},{"key":"2025121401192174000_11.7.e046097.94","unstructured":"World Health Organisation Guidelines . Recommendation on 36 months isoniazid preventive therapy to adults and adolescents living with HIV in resource-constrained and high TB and HIV-prevalence settings: 2015 update, 2015."},{"key":"2025121401192174000_11.7.e046097.95","unstructured":"World Health Organisation HIV Guidelines . Intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource-constrained settings, 2011."},{"key":"2025121401192174000_11.7.e046097.96","unstructured":"Organization WH . Latent tuberculosis infection updated and consolidated guidelines for programmatic management, 2018."},{"key":"2025121401192174000_11.7.e046097.97","unstructured":"Organization WH . Recommendations for management of common childhood conditions newborn conditions, dysentery, pneumonia, oxygen use and delivery, common causes of fever, severe acute malnutrition and supportive care, 2012."},{"key":"2025121401192174000_11.7.e046097.98","unstructured":"Prevention CfDCa . Managing drug interactions in the treatment of HIV-related tuberculosis, 2013."},{"key":"2025121401192174000_11.7.e046097.99","first-page":"211","article-title":"Recommendations on routine screening pelvic examination: Canadian Task force on preventive health care adoption of the American College of physicians guideline","volume":"62","author":"Tonelli","year":"2016","journal-title":"Can Fam Physician"},{"key":"2025121401192174000_11.7.e046097.100","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jclinepi.2017.01.016","article-title":"A methodological survey identified eight proposed frameworks for the adaptation of health related guidelines","volume":"86","author":"Darzi","year":"2017","journal-title":"J Clin Epidemiol"},{"key":"2025121401192174000_11.7.e046097.101","unstructured":"Organization WH . Global antimicrobial resistance and use surveillance system (glass) report, 2020."},{"key":"2025121401192174000_11.7.e046097.102","unstructured":"Organization WH . Worldwide country situation analysis: response to antimicrobial resistance 2015. Available: https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/163468\/9789241564946_eng.pdf?sequence=1"},{"key":"2025121401192174000_11.7.e046097.103","unstructured":"Organization WH . Who model Lists of essential medicines, 2019."},{"key":"2025121401192174000_11.7.e046097.104","unstructured":"Foundation AtM . Antimicrobial resistance benchmark, 2018. 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