{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T10:26:22Z","timestamp":1765880782243,"version":"3.48.0"},"reference-count":19,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"unspecified","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2021,8,6]]},"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Prader\u2013Willi Syndrome (PWS) is one of the rare diseases involving genetics and affects various body systems. The disease is known due to the absence of paternal genes on chromosome 15q11-q13. Multisystem complex conditions require interdisciplinary healthcare treatment. However, to the best of our knowledge, there is little evidence of an established successful model of an interdisciplinary approach in managing rare diseases like PWS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>The scoping review process follows the five-staged Arksey and O\u2019Malley (2005) methodology framework excluding the optional consultation stage (stage 6): the definition of the research questions (step 1); the eligibility criteria and search strategy are defined (stage 2); the study selection process based on the eligibility criteria identified will follow (stage 3); a framework developed for this review will then inform the extraction and charting of data from the included studies (step 4) and results will be aggregated and summarised with criteria relevant for health professionals and policymakers (stage 5). We will search for electronic databases (MEDLINE\/PubMed, Scopus, Web of Science), grey literature sources and critical studies\u2019 reference lists to determine the appropriate inclusion criteria. Three researchers will review all abstracts and full-text studies for inclusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This scoping review methodology does not require ethical approval since it aims to synthesise information from available publications. A scoping review article will be submitted for publication to a scientific journal following this protocol.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2020-047638","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T11:50:19Z","timestamp":1641988219000},"page":"e047638","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Mapping the evidence of multidimensional health approaches in treating individuals with Prader\u2013Willi Syndrome: A scoping review protocol"],"prefix":"10.1136","volume":"12","author":[{"given":"Normah","family":"Che Din","sequence":"first","affiliation":[{"name":"Center for Rehabilitation & Special Needs Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Federal Territory, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9619-4756","authenticated-orcid":false,"given":"Cila","family":"Umat","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation & Special Needs Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Federal Territory, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nor Haniza","family":"Abdul Wahat","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation & Special Needs Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Federal Territory, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azhar Bin","family":"Talib","sequence":"additional","affiliation":[{"name":"Prader-Willi Syndrome Association (PWSA) Malaysia, Jalan Enggang, Taman Keramat, Kuala Lumpur"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"key":"2025121602161039000_12.1.e047638.1","unstructured":"Gutierrez FM . Pathophysiology Prader-Willi Syndrome. In StatPearls [Internet]. StatPearls Publishing, 2020."},{"key":"2025121602161039000_12.1.e047638.2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3345\/kjp.2011.54.2.55","article-title":"Systematic review of the clinical and genetic aspects of Prader-Willi syndrome","volume":"54","author":"Jin","year":"2011","journal-title":"Korean J Pediatr"},{"key":"2025121602161039000_12.1.e047638.3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/473941","article-title":"Prader-Willi syndrome: clinical aspects","volume":"2012","author":"Elena","year":"2012","journal-title":"J Obes"},{"key":"2025121602161039000_12.1.e047638.4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2350-9-89","article-title":"French database of children and adolescents with Prader-Willi syndrome","volume":"9","author":"Molinas","year":"2008","journal-title":"BMC Med Genet"},{"key":"2025121602161039000_12.1.e047638.5","doi-asserted-by":"crossref","first-page":"e514","DOI":"10.1002\/mgg3.514","article-title":"A multidisciplinary approach to the clinical management of Prader-Willi syndrome","volume":"7","author":"Duis","year":"2019","journal-title":"Mol Genet Genomic Med"},{"key":"2025121602161039000_12.1.e047638.6","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czv079"},{"key":"2025121602161039000_12.1.e047638.7","doi-asserted-by":"publisher","DOI":"10.1080\/1364557032000119616"},{"key":"2025121602161039000_12.1.e047638.8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2174\/1573396315666190716120925","article-title":"Prader-Willi Syndrome - Clinical Genetics, Diagnosis and Treatment Approaches: An Update","volume":"15","author":"Butler","year":"2019","journal-title":"Curr Pediatr Rev"},{"key":"2025121602161039000_12.1.e047638.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.chc.2007.03.007"},{"key":"2025121602161039000_12.1.e047638.10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.22.2836"},{"key":"2025121602161039000_12.1.e047638.11","article-title":"Long-Term cost effects of collaborative care for late-life depression","volume":"14","author":"Un\u00fctzer","year":"2008","journal-title":"Am J Manag Care"},{"key":"2025121602161039000_12.1.e047638.12","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2820"},{"key":"2025121602161039000_12.1.e047638.13","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1515\/JPEM.2004.17.9.1153","article-title":"A comprehensive team approach to the management of patients with Prader-Willi syndrome","volume":"17","author":"Eiholzer","year":"2004","journal-title":"J Pediatr Endocrinol Metab"},{"key":"2025121602161039000_12.1.e047638.14","first-page":"199","article-title":"The Prader-Willi syndrome: a self supporting program for children, youngsters and adults","volume":"5","author":"Descheemaeker","year":"1994","journal-title":"Genet Couns"},{"key":"2025121602161039000_12.1.e047638.15","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2010.549288"},{"key":"2025121602161039000_12.1.e047638.16","doi-asserted-by":"publisher","DOI":"10.1186\/1748-5908-5-69"},{"key":"2025121602161039000_12.1.e047638.17","unstructured":"The Joana Briggs Institute . The Joanna Briggs Institute \u201cReviewers\u201d manual 2015 - methodology for JBI scoping reviews. South Australia: Adelaide, 2015."},{"key":"2025121602161039000_12.1.e047638.18","unstructured":"Tyndall J . AACODS checklist. Adelaide, South Australia: Flinders University, 2010."},{"key":"2025121602161039000_12.1.e047638.19","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-036502"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2020-047638","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T10:18:28Z","timestamp":1765880308000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2020-047638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,12]]},"published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1136\/bmjopen-2020-047638"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2020-047638","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}