{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T03:39:52Z","timestamp":1772163592171,"version":"3.50.1"},"reference-count":60,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"unspecified","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institute for Health Research (NIHR), Imperial Biomedical Research Centre"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2021,8,4]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Physical inactivity is more common in older adults, is associated with social isolation and loneliness and contributes to increased morbidity and mortality. We examined the effect of social restrictions to reduce COVID-19 transmission in the UK (lockdown), on physical activity (PA) levels of older adults and the social predictors of any change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Baseline analysis of a survey-based prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Adults enrolled in the Cognitive Health in Ageing Register for Investigational and Observational Trials cohort from general practitioner practices in North West London were invited to participate from April to July 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>6219 cognitively healthy adults aged 50\u201392 years completed the survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Self-reported PA before and after the introduction of lockdown, as measured by metabolic equivalent of task (MET) minutes. Associations of PA with demographic, lifestyle and social factors, mood and frailty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean PA was significantly lower following the introduction of lockdown from 3519 to 3185 MET min\/week (p&lt;0.001). After adjustment for confounders and prelockdown PA, lower levels of PA after the introduction of lockdown were found in those who were over 85 years old (640 (95% CI 246 to 1034) MET min\/week less); were divorced or single (240 (95% CI 120 to 360) MET min\/week less); living alone (277 (95% CI 152 to 402) MET min\/week less); reported feeling lonely often (306 (95% CI 60 to 552) MET min\/week less); and showed symptoms of depression (1007 (95% CI 612 to 1401) MET min\/week less) compared with those aged 50\u201364 years, married, cohabiting and not reporting loneliness or depression, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and implications<\/jats:title>\n                    <jats:p>Markers of social isolation, loneliness and depression were associated with lower PA following the introduction of lockdown in the UK. Targeted interventions to increase PA in these groups should be considered.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2021-050680","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T13:12:18Z","timestamp":1629897138000},"page":"e050680","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":31,"title":["Impact of social restrictions during the COVID-19 pandemic on the physical activity levels of adults aged 50\u201392 years: a baseline survey of the CHARIOT COVID-19 Rapid Response prospective cohort study"],"prefix":"10.1136","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1481-8829","authenticated-orcid":false,"given":"David","family":"Salman","sequence":"first","affiliation":[{"name":"Department of Primary Care and Public Health, Imperial College London, London, UK"},{"name":"MSk Lab, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Beaney","sequence":"additional","affiliation":[{"name":"Department of Primary Care and Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"E Robb","sequence":"additional","affiliation":[{"name":"Ageing Epidemiology Research Unit (AGE), Faculty of Medicine, School of Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0789-3297","authenticated-orcid":false,"given":"Celeste A","family":"de Jager Loots","sequence":"additional","affiliation":[{"name":"Ageing Epidemiology Research Unit (AGE), Faculty of Medicine, School of Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parthenia","family":"Giannakopoulou","sequence":"additional","affiliation":[{"name":"Ageing Epidemiology Research Unit (AGE), Faculty of Medicine, School of Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinedu T","family":"Udeh-Momoh","sequence":"additional","affiliation":[{"name":"Ageing Epidemiology Research Unit (AGE), Faculty of Medicine, School of Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Ahmadi-Abhari","sequence":"additional","affiliation":[{"name":"Ageing Epidemiology Research Unit (AGE), Faculty of Medicine, School of Public Health, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeem","family":"Majeed","sequence":"additional","affiliation":[{"name":"Department of Primary Care and Public Health, Imperial College London, London, UK"},{"name":"Public Health Directorate, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lefkos T","family":"Middleton","sequence":"additional","affiliation":[{"name":"Ageing Epidemiology Research Unit (AGE), Faculty of Medicine, School of Public Health, Imperial College London, London, UK"},{"name":"Public Health Directorate, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison H","family":"McGregor","sequence":"additional","affiliation":[{"name":"MSk Lab, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"2025121515051755000_11.8.e050680.1","unstructured":"NHS Digital . 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