{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T22:37:37Z","timestamp":1765838257604,"version":"3.48.0"},"reference-count":26,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"unspecified","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,2,8]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to determine the variation in the interval between the onset of symptoms and clinical presentation, and its associated factors among symptomatic individuals with gonorrhoea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted between 1 June and 30 July 2017.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>129 sexually transmitted disease clinics from 21 cities of Guangdong, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Using convenience sampling method to recruit symptomatic individuals with gonorrhoea over 18 years old.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome measure<\/jats:title>\n                    <jats:p>Time to clinical presentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 1664 participants, the median age was 29 (24\u201336) years old, and the majority were male (92.5%) and married (52.9%). The median time to clinical presentation was 3 (2\u20136)\u2009days. About 471 (28.3%) patients had sexual contact while symptomatic. After adjusting for covariates, participants who were female (a\u03b2=0.44, 95%\u2009CI: 0.22 to 0.80), from east Guangdong region (a\u03b2=0.44, 95%\u2009CI: 0.22 to 0.80) and had the absence of dysuria (a\u03b2=0.26, 95%\u2009CI: 0.06 to 0.46) had increased time to clinical presentation. Participants who had commercial sex in the past 6 months (a\u03b2=\u22120.11, 95%\u2009CI: \u22120.21 to \u20130.01) had decreased time to clinical presentation. Participants who were female (adjusted odds ratio (aOR)=1.66, 95%\u2009CI: 1.08 to 2.50) and delayed in seeking healthcare more than 7\u2009days (aOR=46.71, 95%\u2009CI: 24.27 to 89.93) were more likely to have sexual contact while symptomatic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The time to clinical presentation for individuals with symptomatic gonorrhoea is variable and a high proportion of participants continued to have sexual behaviour while symptomatic. Strategies to increase health literacy may help to minimise the sequelae of gonorrhoea and reduce onward transmission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2021-052586","type":"journal-article","created":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T11:22:45Z","timestamp":1646392965000},"page":"e052586","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Correlates of time to clinical presentation for symptomatic individuals with gonorrhoea in South China: results from a cross-sectional study"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9334-3744","authenticated-orcid":false,"given":"Peizhen","family":"Zhao","sequence":"first","affiliation":[{"name":"STD Control Department, Dermatology Hospital of Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Nie","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital of Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanhuan","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiming","family":"Tang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital of Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"},{"name":"Project-China, University of North Carolina at Chapel Hill, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9846-975X","authenticated-orcid":false,"given":"Heping","family":"Zheng","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital of Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Yang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital of Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8000-9969","authenticated-orcid":false,"given":"Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"STD Control Department, Dermatology Hospital of Southern Medical University, Guangzhou, China"},{"name":"STD Control Department, Southern Medical University Institute for Global Health and Sexually Transmitted Diseases, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,4]]},"reference":[{"key":"2025121514332944000_12.3.e052586.1","unstructured":"China CDC . 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