{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:24:11Z","timestamp":1791390251741,"version":"4.3.3"},"reference-count":27,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T00:00:00Z","timestamp":1657238400000},"content-version":"unspecified","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,6,17]]},"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to assess the morbidity and mortality patterns of preterm neonates with low birth weight admitted in the Amhara region referral hospitals in Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Hospital-based retrospective follow-up study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Amhara region referral hospitals, Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 291 preterm neonates low birth weight that were admitted to referral hospitals in the Amhara region between 1 January 2017\u2009and 30 December 2018 were reviewed. Data were entered into Epi-data V.4.4.2.1 and exported to STATA V.14 for analysis, and variables with a p value of &lt;0.05 at 95% confidence level in multivariable logistic regression model analysis were declared as statistically significant associated factors of mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Primary outcome<\/jats:title>\n                    <jats:p>Morbidity and mortality patterns in preterm low birthweight neonates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study revealed that 37.8% (95% CI 32.4% to 43.5%) of preterm low birthweight neonates died. The most common morbidities found were 219 (75.26%) hypothermia, followed by 201 (69.07%), 145 (49.83%), 39 (13.4%) and 24 (8.25%) with sepsis, respiratory distress, jaundice and congenital anomalies, respectively. Sepsis (AOR: 2.0; 95%\u2009CI 1.03 to 3.89), respiratory distress (AOR: 4.6; 95%\u2009CI 2.51 to 8.40), hypoglycaemia (AOR 3.91; 95%\u2009CI 1.09 to 10.52), APGAR score at fifth minute &lt;7 (AOR 0.39; 95%\u2009CI (0.18 to 0.82) and duration of hospital stay below mean (&lt;9.82\u2009days) (AOR 0.17; 95%\u2009CI 0.09 to 0.33) were associated with mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The mortality rate of preterm low birthweight neonates was high, indicating that this is a public health issue. Hypothermia, sepsis, respiratory distress, jaundice and congenital anomalies were the common morbidities. Sepsis, respiratory distress, hypoglycaemia, Apgar score at fifth minute &lt;7\u2009and duration of hospital stay below the mean were independent factors of mortality. However, these need to be further investigated in future research and appropriately addressed using prospective follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2021-054574","type":"journal-article","created":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T10:37:29Z","timestamp":1657276649000},"page":"e054574","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":22,"title":["Morbidity and mortality patterns of preterm low birthweight neonates admitted to referral hospitals in the Amhara region of Ethiopia: retrospective follow-up study"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3764-3646","authenticated-orcid":false,"given":"Yalemtsehay Dagnaw","family":"Genie","sequence":"first","affiliation":[{"name":"Department of Nursing, Mizan-Tepi University, Mizan, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8283-9667","authenticated-orcid":false,"given":"Belete Fenta","family":"Kebede","sequence":"additional","affiliation":[{"name":"School of Midwifery, Jimma University, Jimma, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1943-041X","authenticated-orcid":false,"given":"Mulualem","family":"Silesh Zerihun","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Debre Berhan University, Debre Berhan, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3636-6402","authenticated-orcid":false,"given":"Desalew","family":"Tilahun Beyene","sequence":"additional","affiliation":[{"name":"Department of Nursing, Jimma University, Jimma, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,7,8]]},"reference":[{"key":"2025121404013815000_12.7.e054574.1","first-page":"20","article-title":"Survive & thrive","volume":"29","year":"2019","journal-title":"Delic Living"},{"key":"2025121404013815000_12.7.e054574.2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-2471"},{"key":"2025121404013815000_12.7.e054574.3","unstructured":"Article O . 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