{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:19:08Z","timestamp":1790889548665,"version":"4.1.0"},"reference-count":51,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T00:00:00Z","timestamp":1652832000000},"content-version":"unspecified","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Perinatal mortality is an important outcome indicator for newborn care and directly mirrors the quality of prenatal, intra partum and newborn care. Therefore, this study was aimed at estimating perinatal mortality and its predictors in Eastern Ethiopia using data from Kersa Health and Demographic Surveillance System (KHDSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, settings and participants<\/jats:title><jats:p>An open dynamic cohort design was employed among pregnant women from 2015 to 2020 at KHDSS. A total of 19\u2009687\u2009women were observed over the period of 6\u2009years, and 29\u2009719 birth outcomes were registered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Outcome measures<\/jats:title><jats:p>Perinatal mortality rate was estimated for each year of cohort and the cumulative of 6\u2009years. Predictors of perinatal mortality are identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From a total of 29\u2009306 births 783 (26.72 deaths per 1000 births; 95%\u2009CI 24.88 to 28.66) deaths were occurred during perinatal period. Rural residence (adjusted OR (AOR)=3.43; 95%\u2009CI 2.04 to 5.76), birth weight (low birth weight, AOR=3.98; 95% CI 3.04 to 5.20; big birth weight, AOR=2.51; 95% CI 1.76 to 3.57), not having antenatal care (ANC) (AOR=1.67; 95% CI 1.29 to 2.17) were associated with higher odds of perinatal mortality whereas the parity (multipara, AOR=0.46; 95%\u2009CI 0.34 to 0.62; grand multipara, AOR=0.31; 95%\u2009CI 0.21 to 0.47) was associated with lower odds of perinatal mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study revealed relatively high perinatal mortality rate. Place of residence, ANC, parity and birth weight were identified as predictors of perinatal mortality. Devising strategies that enhance access to and utilisations of ANC services with due emphasis for rural residents, primipara mothers and newborn with low and big birth weights may be crucial for reducing perinatal mortality.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bmjopen-2021-054975","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T15:41:19Z","timestamp":1652888479000},"page":"e054975","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Perinatal mortality and its predictors in Kersa Health and Demographic Surveillance System, Eastern Ethiopia: population-based prospective study from 2015 to 2020"],"prefix":"10.1136","volume":"12","author":[{"given":"Merga","family":"Dheresa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamachis","family":"Daraje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gelana","family":"Fekadu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galana Mamo","family":"Ayana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bikila","family":"Balis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belay","family":"Negash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Temam Beshir","family":"Raru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yadeta","family":"Dessie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Addisu","family":"Alemu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8178-6484","authenticated-orcid":false,"given":"Bedasa Taye","family":"Merga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,5,18]]},"reference":[{"key":"2022063010162041000_12.5.e054975.1","doi-asserted-by":"crossref","unstructured":"Bakketeig LS , Bergsj\u00f8 P , Epidemiology P . International encyclopedia of public health. Oxford: Academic Press, 2008: 45\u201353.","DOI":"10.1016\/B978-012373960-5.00199-4"},{"key":"2022063010162041000_12.5.e054975.2","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2471\/BLT.16.179531","article-title":"Developing global indicators for quality of maternal and newborn care: a feasibility assessment","volume":"95","author":"Madaj","year":"2017","journal-title":"Bull World Health Organ"},{"key":"2022063010162041000_12.5.e054975.3","unstructured":"EMI SUZUKI HK . A neglected burden: the global tragedy of stillbirths stillbirths: report of the un Inter-Agency group for child mortality estimation, 2020. Available: https:\/\/blogs.worldbank.org\/opendata\/first-ever-un-report-global-stillbirths-reveals-enormous-and-neglected-toll"},{"key":"2022063010162041000_12.5.e054975.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31575-6"},{"key":"2022063010162041000_12.5.e054975.5","unstructured":"Estimation UNIGfCM . Levels & Trends in Child Mortality: Report 2017: Estimates Developed by the UN Inter-Agency Group for Child Mortality Estimation. United Nations Children\u2019s Fund, 2017."},{"key":"2022063010162041000_12.5.e054975.6","article-title":"Perinatal mortality in sub-Saharan Africa: a meta-analysis of demographic and health surveys","volume":"85","author":"Akombi","year":"2019","journal-title":"Ann Glob Health"},{"key":"2022063010162041000_12.5.e054975.7","unstructured":"Central Statistical Agency E . Ethiopia demographic and health survey 2016. Addis Ababa, Ethiopia, and Rockville, Maryland, USA: CSA and ICF, 2016."},{"key":"2022063010162041000_12.5.e054975.8","unstructured":"Assembly UG . Sustainable development goals (SDGs), transforming our world: the, 2030. United Nations New York, 2015."},{"key":"2022063010162041000_12.5.e054975.9","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.06.035659"},{"key":"2022063010162041000_12.5.e054975.10","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-14-1"},{"key":"2022063010162041000_12.5.e054975.11","unstructured":"EDHS . Ethiopia demographic and health survey. Available: https:\/\/dhsprogram.com\/pubs\/pdf\/FR328\/FR328.pdf [Accessed 21 Oct 2020]."},{"key":"2022063010162041000_12.5.e054975.12","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-018-6293-9"},{"key":"2022063010162041000_12.5.e054975.13","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-09301-4"},{"key":"2022063010162041000_12.5.e054975.14","doi-asserted-by":"crossref","unstructured":"Yemisrach G , Mesganaw F . Factors associated with perinatal mortality among public health deliveries in Addis Ababa, Ethiopia, an unmatched case control study. BMC Pregnancy Childbirth 2017;17.","DOI":"10.1186\/s12884-017-1420-7"},{"key":"2022063010162041000_12.5.e054975.15","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jped.2012.11.005","article-title":"Determinants of neonatal death with emphasis on health care during pregnancy, childbirth and reproductive history","volume":"89","author":"Kassar","year":"2013","journal-title":"J Pediatr"},{"key":"2022063010162041000_12.5.e054975.16","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-018-5757-2","article-title":"Determinants of perinatal mortality among cohorts of pregnant women in three districts of North Showa zone, Oromia region, Ethiopia: community based nested case control study","volume":"18","author":"Roro","year":"2018","journal-title":"BMC Public Health"},{"key":"2022063010162041000_12.5.e054975.17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02245.x"},{"key":"2022063010162041000_12.5.e054975.18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-14-1"},{"key":"2022063010162041000_12.5.e054975.19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0242499","article-title":"Spatial pattern of perinatal mortality and its determinants in Ethiopia: data from Ethiopian demographic and health survey 2016","volume":"15","author":"Yadeta","year":"2020","journal-title":"PLoS One"},{"key":"2022063010162041000_12.5.e054975.20","unstructured":"Network EURC . Trends and causes of perinatal death in Ethiopia, 2010-2014, 2016."},{"key":"2022063010162041000_12.5.e054975.21","unstructured":"CSA I . Key indicators: mini demographic and health survey, 2019."},{"key":"2022063010162041000_12.5.e054975.22","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s40748-016-0035-8","article-title":"Neonatal mortality and causes of death in Kersa health and demographic surveillance system (Kersa HDSS), Ethiopia, 2008-2013","volume":"2","author":"Assefa","year":"2016","journal-title":"Matern Health Neonatol Perinatol"},{"key":"2022063010162041000_12.5.e054975.23","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv284"},{"key":"2022063010162041000_12.5.e054975.24","unstructured":"Organization WH . Neonatal and perinatal mortality: country, regional and global estimates. World Health Organization, 2006."},{"key":"2022063010162041000_12.5.e054975.25","doi-asserted-by":"crossref","unstructured":"Kassaw MW , Abebe AM , Kassie AM , et al . Trends of proximate low birth weight and associations among children under-five years of age: evidence from the 2016 Ethiopian demographic and health survey data. PLoS One 2021;16:e0246587.doi:10.1371\/journal.pone.0246587","DOI":"10.1371\/journal.pone.0246587"},{"key":"2022063010162041000_12.5.e054975.26","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/j.1471-0528.2007.01435.x","article-title":"The interpretation and clinical application of the word 'parity': a survey","volume":"114","author":"Opara","year":"2007","journal-title":"BJOG"},{"key":"2022063010162041000_12.5.e054975.27","unstructured":"Organization WH . Making pregnancy safer: the critical role of the skilled attendant: a joint statement by WHO, ICM and FIGO. World health organization, 2004."},{"key":"2022063010162041000_12.5.e054975.28","doi-asserted-by":"crossref","unstructured":"Woldeamanuel BT , Gelebo KK . Statistical analysis of socioeconomic and demographic correlates of perinatal mortality in Tigray region, Ethiopia: a cross sectional study. BMC Public Health 2019;19:1301.doi:10.1186\/s12889-019-7642-z","DOI":"10.1186\/s12889-019-7642-z"},{"key":"2022063010162041000_12.5.e054975.29","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-1"},{"key":"2022063010162041000_12.5.e054975.30","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4314\/ejhs.v25i2.1","article-title":"Ethiopia successfully attaining the millennium development goals","volume":"25","author":"Haileamlak","year":"2015","journal-title":"Ethiop J Health Sci"},{"key":"2022063010162041000_12.5.e054975.31","doi-asserted-by":"crossref","unstructured":"Tesfaye Assebe Y , Bizatu M , Tesfaye G . Spatial pattern of perinatal mortality and its determinants in Ethiopia: data from Ethiopian demographic and health survey 2016. PLoS ONE 2020;15.doi:10.1371\/journal.pone.0242499","DOI":"10.1371\/journal.pone.0242499"},{"key":"2022063010162041000_12.5.e054975.32","doi-asserted-by":"crossref","unstructured":"Girmatsion F , Berhane Yemane A , Alemayehu W . Distance from health facility and mothers\u2019 perception of quality related to skilled delivery service utilization in northern Ethiopia. Int J Womens Health 2017.doi:10.2147\/IJWH.S140366","DOI":"10.2147\/IJWH.S140366"},{"key":"2022063010162041000_12.5.e054975.33","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ijgo.2011.07.009","article-title":"Ethiopia's assessment of emergency obstetric and newborn care: setting the gold standard for national facility-based assessments","volume":"115","author":"Keyes","year":"2011","journal-title":"Int J Gynaecol Obstet"},{"key":"2022063010162041000_12.5.e054975.34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216037","article-title":"Pregnancies with an outcome of fetal death present higher risk of delays in obstetric care: a case-control study","volume":"14","author":"Martins","year":"2019","journal-title":"PLoS One"},{"key":"2022063010162041000_12.5.e054975.35","doi-asserted-by":"crossref","first-page":"55","DOI":"10.4314\/ejhs.v24i0.6S","article-title":"A meta-analysis of selected maternal and fetal factors for perinatal mortality","volume":"24 Suppl","author":"Berhan","year":"2014","journal-title":"Ethiop J Health Sci"},{"key":"2022063010162041000_12.5.e054975.36","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-015-0429-z"},{"key":"2022063010162041000_12.5.e054975.37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5402\/2011\/259308","article-title":"Incidence of obstetric and foetal complications during labor and delivery at a community health centre, midwives obstetric unit of Durban, South Africa","volume":"2011","author":"Hoque","year":"2011","journal-title":"ISRN Obstet Gynecol"},{"key":"2022063010162041000_12.5.e054975.38","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmt075"},{"key":"2022063010162041000_12.5.e054975.39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019674"},{"key":"2022063010162041000_12.5.e054975.40","doi-asserted-by":"crossref","first-page":"299","DOI":"10.11604\/pamj.2017.28.299.1269","article-title":"Incidence and determinants of stillbirth among women who gave birth in Jimma university specialized Hospital, Ethiopia","volume":"28","author":"Tilahun","year":"2017","journal-title":"Pan Afr Med J"},{"key":"2022063010162041000_12.5.e054975.41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/9097415","article-title":"Birth preparedness and complication readiness among pregnant women in a secondary health facility in Abakaliki, Ebonyi state, Nigeria","volume":"2020","author":"Anikwe","year":"2020","journal-title":"Biomed Res Int"},{"key":"2022063010162041000_12.5.e054975.42","unstructured":"Darby A . \u201cDelayed Breastfeeding Initiation Increases Risk of Neonatal Mortality\u201d(2006), by Karen Edmond Charles Zandoh, Maria Quigley, Seeba Amenga-Etego, Seth Oqusi-Agyei, and Betty Kirkwood. Embryo Project Encyclopedia 2019."},{"key":"2022063010162041000_12.5.e054975.43","doi-asserted-by":"publisher","DOI":"10.1186\/1475-9276-13-1"},{"key":"2022063010162041000_12.5.e054975.44","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1111\/ans.16148","article-title":"Universal access to safe, affordable, timely surgical and anaesthetic care in Papua New Guinea: the six global health indicators","volume":"90","author":"James","year":"2020","journal-title":"ANZ J Surg"},{"key":"2022063010162041000_12.5.e054975.45","unstructured":"Organization WH . WHO recommendations on antenatal care for a positive pregnancy experience. World Health Organization, 2016."},{"key":"2022063010162041000_12.5.e054975.46","doi-asserted-by":"crossref","DOI":"10.1186\/s12887-021-02598-z","article-title":"Neonatal mortality among neonates admitted to NICU of Hiwot Fana specialized university Hospital, eastern Ethiopia, 2020: a cross-sectional study design","volume":"21","author":"Eyeberu","year":"2021","journal-title":"BMC Pediatr"},{"key":"2022063010162041000_12.5.e054975.47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/5351010","article-title":"Prevalence and associated factors of perinatal asphyxia among neonates in general hospitals of Tigray, Ethiopia, 2018","volume":"2018","author":"Gebreheat","year":"2018","journal-title":"Biomed Res Int"},{"key":"2022063010162041000_12.5.e054975.48","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2010.09.039"},{"key":"2022063010162041000_12.5.e054975.49","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.006513"},{"key":"2022063010162041000_12.5.e054975.50","first-page":"765","volume-title":"The role of surfactant in lung disease and host defense against pulmonary infections","volume":"12","author":"Han","year":"2015"},{"key":"2022063010162041000_12.5.e054975.51","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00006.2010"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2021-054975","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T17:28:27Z","timestamp":1656610107000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2021-054975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":51,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5,18]]},"published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1136\/bmjopen-2021-054975"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2021-054975","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}