{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T08:05:11Z","timestamp":1765699511005,"version":"3.48.0"},"reference-count":59,"publisher":"BMJ","issue":"2","license":[{"start":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T00:00:00Z","timestamp":1645401600000},"content-version":"unspecified","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,1,28]]},"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Multiple symptoms occur in people with kidney failure receiving haemodialysis (HD) and these symptoms have a negative impact on health-related quality of life (HRQoL). Fatigue, the most common symptom, is debilitating and difficult to manage. Educational interventions involving energy conservation strategies are helpful in reducing fatigue, however the effectiveness of energy conservation has not been previously studied in those receiving HD. The aim of this study is to evaluate the effectiveness of an energy conservation education intervention for people with end-stage kidney disease receiving HD (EVEREST trial).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>A pragmatic cluster randomised control trial with repeated measure will be used. One hundred and twenty-six participants from tertiary level dialysis centre will be cluster randomised to the intervention and control group according to HD treatment day. The intervention group will receive usual care along with a structured energy conservation education programme over 12 weeks comprising three individual face-to-face educational intervention sessions, one booster session and a booklet. The control group will receive usual care from their healthcare providers and a booklet at the end of the study. The primary outcome is fatigue, and the secondary outcomes are other Chronic Kidney Disease (CKD) symptoms, occupational performance and HRQoL. Intention-to-treat analysis will occur and will include a change in primary and secondary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethical approval has been obtained from the Human Research Committee of the Griffith University and Nepal Health Research Council. The results of this research will be published and presented in a variety of forums.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial pre-results\" xlink:href=\"NCT04360408\">NCT04360408<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2021-056544","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T12:28:36Z","timestamp":1645446516000},"page":"e056544","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Energy conservation education intervention for people with end-stage kidney disease receiving haemodialysis (EVEREST): protocol for a cluster randomised control trial"],"prefix":"10.1136","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct04360408","registry":"10.18810\/clinical-trials-gov","type":"preResults"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9136-1810","authenticated-orcid":false,"given":"Sita","family":"Sharma","sequence":"first","affiliation":[{"name":"School of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia"},{"name":"Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly E","family":"Alexander","sequence":"additional","affiliation":[{"name":"School of Nursing, Queensland University of Technology, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa","family":"Green","sequence":"additional","affiliation":[{"name":"School of Nursing, Midwifery and Social Work, The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Surgical Treatment and Rehabilitation Service, Metro North Hospital and Health Service, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min-Lin (Winnie)","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia"},{"name":"Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9920-6743","authenticated-orcid":false,"given":"Ann","family":"Bonner","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia"},{"name":"Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia"},{"name":"Kidney Health Service, Royal Brisbane and Women\u2019s Hospital, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,2,21]]},"reference":[{"key":"2025121400003685000_12.2.e056544.1","doi-asserted-by":"publisher","DOI":"10.1038\/kisup.2013.3"},{"key":"2025121400003685000_12.2.e056544.2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158765"},{"key":"2025121400003685000_12.2.e056544.3","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/S0140-6736(16)32064-5","article-title":"Chronic kidney disease","volume":"389","author":"Webster","year":"2017","journal-title":"The Lancet"},{"key":"2025121400003685000_12.2.e056544.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.02.010"},{"key":"2025121400003685000_12.2.e056544.5","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/hdi.12629","article-title":"Free dialysis in Nepal: logistical challenges explored","volume":"22","author":"Mcgee","year":"2018","journal-title":"Hemodial Int"},{"key":"2025121400003685000_12.2.e056544.6","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000002767","article-title":"Comparison of clinical outcome between twice-weekly and Thrice-Weekly hemodialysis in patients with residual kidney function","volume":"95","author":"Hwang","year":"2016","journal-title":"Medicine"},{"key":"2025121400003685000_12.2.e056544.7","unstructured":"Sinclair A , Cimon K , Loncar M , et al . 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