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Photobiomodulation therapy has been highlighted as one promising option. A whole-body therapy device (NovoTHOR) has recently been developed with a number of potential advantages for people with chronic pain. Research is needed to consider the feasibility of this device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and analysis<\/jats:title><jats:p>A single-centre single-armed (no placebo group) feasibility study with an embedded qualitative component will be conducted. The intervention will comprise 18 treatments over 6 weeks, with 6-month follow-up, in the whole-body photobiomodulation device. A non-probability sample of 20 adult participants with a clinician diagnosis of chronic axial pain, polyarthralgia, myofascial pain or widespread pain will be recruited (self-referral and clinician referral). Outcome measures will focus on acceptability of trial processes with a view to guiding a definitive randomised controlled trial. Analyses will use descriptive statistics for quantitative aspects. The qualitative element will be assessed by means of a participant-reported experience questionnaire postintervention and semistructured audio-recorded interviews at three stages; preintervention, midintervention and postintervention. The latter will be transcribed verbatim and a reflexive thematic analysis will be used to identify emerging themes. Exploratory outcomes (participant-reported and performance-based measures) will be analysed according to data distribution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ethics and dissemination<\/jats:title><jats:p>The study has received ethical approval from the Leicester Central Research and Ethics Committee. Findings will be disseminated via local chronic pain groups, public register update, submission for presentation at scientific meetings and open-access peer-reviewed journals, and via academic social networks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial registration number<\/jats:title><jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT05069363\">NCT05069363<\/jats:ext-link>.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bmjopen-2021-060058","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T15:56:34Z","timestamp":1656518194000},"page":"e060058","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Whole-body photobiomodulation therapy for chronic pain: a protocol for a feasibility trial"],"prefix":"10.1136","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct05069363","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7365-4177","authenticated-orcid":false,"given":"Bethany","family":"Fitzmaurice","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7599-3674","authenticated-orcid":false,"given":"Nicola R","family":"Heneghan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asius","family":"Rayen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5118-5872","authenticated-orcid":false,"given":"Andrew","family":"Soundy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"2022062908550989000_12.6.e060058.1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001939"},{"key":"2022062908550989000_12.6.e060058.2","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000160"},{"key":"2022062908550989000_12.6.e060058.3","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.pnpbp.2018.01.017","article-title":"Evaluating psychosocial contributions to chronic pain outcomes","volume":"87","author":"Meints","year":"2018","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"2022062908550989000_12.6.e060058.4","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001384"},{"key":"2022062908550989000_12.6.e060058.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.03.023"},{"key":"2022062908550989000_12.6.e060058.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9"},{"key":"2022062908550989000_12.6.e060058.7","doi-asserted-by":"crossref","DOI":"10.1186\/s12891-019-2555-7","article-title":"The prevalence of chronic pain and its associated factors among Saudi Al-Kharj population; a cross sectional study","volume":"20","author":"El-Metwally","year":"2019","journal-title":"BMC Musculoskelet Disord"},{"key":"2022062908550989000_12.6.e060058.8","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines5020020","article-title":"Update on treatment guideline in fibromyalgia syndrome with focus on pharmacology","volume":"5","author":"Kia","year":"2017","journal-title":"Biomedicines"},{"key":"2022062908550989000_12.6.e060058.9","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1586\/14737167.2013.851006","article-title":"Economic implications of potential drug\u2013drug interactions in chronic pain patients","volume":"13","author":"Taylor","year":"2013","journal-title":"Expert Rev Pharmacoeconomics Outcomes Res"},{"key":"2022062908550989000_12.6.e060058.10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.15171\/jlms.2019.02","article-title":"The use of laser therapy for patients with fibromyalgia: a critical literary review","volume":"10","author":"Kisselev","year":"2019","journal-title":"J Lasers Med Sci"},{"key":"2022062908550989000_12.6.e060058.11","unstructured":"National Institute for Health and Care Excellence . 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