{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T12:31:06Z","timestamp":1774701066567,"version":"3.50.1"},"reference-count":16,"publisher":"BMJ","issue":"6","license":[{"start":{"date-parts":[[2022,6,12]],"date-time":"2022-06-12T00:00:00Z","timestamp":1654992000000},"content-version":"unspecified","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"World Health Organization, Vietnam Country Office","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,5,26]]},"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The goal of this study was to describe the burden of disease and in-hospital mortality among patients admitted to the critical care units (CCUs) in Vietnam.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>The whole 1-year data of admissions to CCUs were collected from 34 hospitals from January to December 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 44\u2009013 episodes of admission to CCUs were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Primary outcome<\/jats:title>\n                    <jats:p>We used International Classification of Diseases-11 codes to assess the primary diagnosis associated with admissions and in-hospitals mortality. Years of life lost (YLL) measure was further used to estimate the burden of disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The 0\u20135 years and \u226570 years age groups accounted for 14.8% (6508\/44 013) and 26.1% (11 480\/44 013) of all admissions, respectively. The most common diagnoses were diseases of the respiratory system (27.8% or 12 255\/44 013), followed by unclassified symptoms, signs or clinical findings (13% or 5712\/44 013), and diseases of the circulatory system (12.2% or 5380\/44 013). Among 28\u2009311 patients with available outcome data, 1681 individuals (5.9%) died during the hospitalisation. The in-hospital mortality rate increased with age, from 2.8% (86\/3105) in under 5 years old age group to 23.1% (297\/1288) in over 90-year age group. Diseases of the respiratory system was the leading causes of death in term of number of deaths (21.8% or 367\/1681 of all deaths). Diagnosis of sepsis was associated with the highest in-hospital mortality (36.8%). The overall YLL under the age of 75 were 1287 per 1000 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CCUs in Vietnam faced wide differences in the burden of diseases. Sufficient infrastructure and adequate multidisciplinary training are essential to ensure the appropriate response to the current needs of population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-061638","type":"journal-article","created":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T11:31:50Z","timestamp":1655119910000},"page":"e061638","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Causes of admissions and in-hospital mortality among patients admitted to critical care units in primary and secondary hospitals in Vietnam in 2018: a multicentre retrospective study"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5904-5970","authenticated-orcid":false,"given":"Vu Quoc","family":"Dat","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Hanoi Medical University, Hanoi, Viet Nam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7337-5925","authenticated-orcid":false,"given":"Bui Thi Khanh","family":"Linh","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Hanoi Medical University, Hanoi, Viet Nam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giang Bao","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Viet Nam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,6,13]]},"reference":[{"key":"2025121513295698000_12.6.e061638.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2018-000733"},{"key":"2025121513295698000_12.6.e061638.2","unstructured":"World Health Assembly . Emergency care systems for universal health coverage: ensuring timely care for the acutely ill and injured. Geneva: World Health Organization, 2019."},{"key":"2025121513295698000_12.6.e061638.3","unstructured":"Executive Board . International classification of diseases: international statistical classification of diseases and related health problems: update on the eleventh revision: report by the director-general. Geneva: World Health Organization, 2018."},{"key":"2025121513295698000_12.6.e061638.4","unstructured":"Glinskaya E , Feige ADK , Hoang VTL . Vietnam - adapting to an aging society. Washington, DC: World Bank Group, 2021."},{"key":"2025121513295698000_12.6.e061638.5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-015260"},{"key":"2025121513295698000_12.6.e061638.6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0190755","article-title":"Completeness and reliability of mortality data in Viet Nam: implications for the National routine health management information system","volume":"13","author":"Hong","year":"2018","journal-title":"PLoS One"},{"key":"2025121513295698000_12.6.e061638.7","doi-asserted-by":"publisher","DOI":"10.1136\/injuryprev-2017-042341"},{"key":"2025121513295698000_12.6.e061638.8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116949"},{"key":"2025121513295698000_12.6.e061638.9","unstructured":"World Health Organization . WHO methods and data sources for global burden of disease estimates 2000-2019. In: Analytics DoDa, division of data AaDfI. Geneva: World Health Organization, 2020."},{"key":"2025121513295698000_12.6.e061638.10","unstructured":"World Health Organization . Life expectancy and healthy life expectancy. Data by country 2020, 2021. Available: https:\/\/apps.who.int\/gho\/data\/node.main.688 [Accessed 6 Jan 2022]."},{"key":"2025121513295698000_12.6.e061638.11","doi-asserted-by":"crossref","first-page":"28","DOI":"10.5365\/wpsar.2021.12.4.835","article-title":"Capacity and use of diagnostics and treatment for patients with severe acute respiratory infections in the pre-COVID-19 era in district and provincial hospitals in Viet Nam","volume":"12","author":"Dat","year":"2021","journal-title":"Western Pac Surveill Response JWPSAR"},{"key":"2025121513295698000_12.6.e061638.12","unstructured":"World Health Organization . The top 10 causes of death 2019, 2020. Available: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/the-top-10-causes-of-death [Accessed 11 Dec 2021]."},{"key":"2025121513295698000_12.6.e061638.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9"},{"key":"2025121513295698000_12.6.e061638.14","unstructured":"World Health Organization . Global health estimates 2020: deaths by cause, age, sex, by country and by region, 2000-2019, 2020. Available: https:\/\/www.who.int\/data\/gho\/data\/themes\/mortality-and-global-health-estimates\/ghe-leading-causes-of-death [Accessed 13 Dec 2021]."},{"key":"2025121513295698000_12.6.e061638.15","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.14.148338"},{"key":"2025121513295698000_12.6.e061638.16","unstructured":"General Statistic Office, United Nations Population Fund . Vietnam population projection for the period 2019-2069. Hanoi: General Statistic Office, United Nations Population Fund, 2020."}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2022-061638","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T21:30:05Z","timestamp":1765834205000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2022-061638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":16,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,6,13]]},"published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1136\/bmjopen-2022-061638"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2022-061638","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}