{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T08:50:20Z","timestamp":1765702220188,"version":"3.48.0"},"reference-count":29,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"unspecified","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,10,26]]},"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Anterior shoulder dislocation is a common reason for consultation at the emergency department (ED). Hypnosis could be a safe and effective alternative therapy for pain relief during shoulder dislocation reduction but nowadays, evidence is not sufficient. The main objective of this study is to show that reduction under hypnosis is associated with a decrease in the use of analgesic compared with usual care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>We will conduct an interventional, controlled, multicentre, randomised study. A total of 44 patients with shoulder dislocation will be randomised in two groups: the hypnosis group (N=22) and the usual care group (N=22). The primary endpoint will be the comparison of morphine equivalent analgesic consumption during a shoulder dislocation reduction manoeuvre. Secondary endpoints will include haemodynamic parameters monitoring, patient and practitioner satisfaction using a Likert scale, use of coanalgesic or sedative drugs, number of reduction attempts and time spent at ED. Adverse events will be recorded. Statistical analysis will include parametric tests, multivariate linear regression and descriptive statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This study has received ethics approval from the Comit\u00e9 de Protection des Personnes of Sud-Est IV on 03\/11\/2021 (ANSM informed on 19 November 2021). The results will be published in scientific articles and communicated in national and international conferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      ClinicalTrial.gov:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04992598\">NCT04992598<\/jats:ext-link>\n                      ; National Clinical trial no ID RCB : 2021-A01382-39\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-062278","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T09:20:52Z","timestamp":1670404852000},"page":"e062278","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Study protocol: hypnosis versus standard care for shoulder dislocation reduction in the emergency department \u2013 a multicentre, randomised, controlled study protocol"],"prefix":"10.1136","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct04992598","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04992598","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Marion","family":"Tinelli","sequence":"first","affiliation":[{"name":"Facult\u00e9 de m\u00e9decine, Universit\u00e9 de Lyon, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazmine","family":"Guler","sequence":"additional","affiliation":[{"name":"Emergency Department, CHR Metz-Thionville, Metz, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Goetz","sequence":"additional","affiliation":[{"name":"Clinical Research Support Unit, CHR Metz-Thionville, Metz, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Aim","sequence":"additional","affiliation":[{"name":"Psychiatre Lib\u00e9ral, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Marchionni","sequence":"additional","affiliation":[{"name":"Clinical Research Support Unit, CHR Metz-Thionville, Metz, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Ouamara","sequence":"additional","affiliation":[{"name":"Psychiatre Lib\u00e9ral, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauriane","family":"Cipolat","sequence":"additional","affiliation":[{"name":"Emergency Department, CHR Metz-Thionville, Metz, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marine","family":"Demarquet","sequence":"additional","affiliation":[{"name":"CH Bourg-en-Bresse, Bourg-en-Bresse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Seris","sequence":"additional","affiliation":[{"name":"CH Sargueminnes, Sargueminnes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexia","family":"Moreau","sequence":"additional","affiliation":[{"name":"CH Vienne, Vienne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Durand","sequence":"additional","affiliation":[{"name":"CH Villefranche sur saones, Villefranche sur saones, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Douplat","sequence":"additional","affiliation":[{"name":"Service d\u2019urgences m\u00e9dicales et chirurgicales - Centre hospitalier Edouard Herriot, Hospices Civils de Lyon, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Pierre","family":"Lavignon","sequence":"additional","affiliation":[{"name":"Saint Joseph Saint Luc Hospital Anesthesia-Resuscitation, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coraline","family":"Hingray","sequence":"additional","affiliation":[{"name":"Pole de psychiatrie universitaire du grand Nancy, CPN, Laxou, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2527-8458","authenticated-orcid":false,"given":"Laure","family":"Abensur Vuillaume","sequence":"additional","affiliation":[{"name":"Emergency Department, CHR Metz-Thionville, Metz, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"2025121400474244000_12.12.e062278.1","unstructured":"Walls R , Hockberger R , Gausche-Hill M . Rosen\u2019s emergency medicine: concepts and clinical practice. 9th \u00e9d. Californie: Elsevier, 2017: 2688 p."},{"key":"2025121400474244000_12.12.e062278.2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.I.00450"},{"key":"2025121400474244000_12.12.e062278.3","doi-asserted-by":"publisher","DOI":"10.1136\/emj.15.1.7"},{"key":"2025121400474244000_12.12.e062278.4","doi-asserted-by":"crossref","DOI":"10.1186\/s13018-015-0226-4","article-title":"Comparison of four different reduction methods for anterior dislocation of the shoulder","volume":"10","author":"Guler","year":"2015","journal-title":"J Orthop Surg Res"},{"key":"2025121400474244000_12.12.e062278.5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-013676"},{"key":"2025121400474244000_12.12.e062278.6","unstructured":"Bijok B , Huet DG . Quelle anesth\u00e9sie en urgence pour une luxation d\u2019un membre? 2019;21."},{"key":"2025121400474244000_12.12.e062278.7","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200204000-00031"},{"key":"2025121400474244000_12.12.e062278.8","first-page":"934","volume-title":"S\u00e9dation et analg\u00e9sie en structure d\u2019urgence (R\u00e9actualisation de la Conf\u00e9rence d\u2019experts de la SFAR de 1999)","volume":"29","year":"2010"},{"key":"2025121400474244000_12.12.e062278.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2013.10.015"},{"key":"2025121400474244000_12.12.e062278.10","doi-asserted-by":"publisher","DOI":"10.1080\/00207144.2014.961870"},{"key":"2025121400474244000_12.12.e062278.11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.neubiorev.2017.02.020","article-title":"Brain correlates of hypnosis: a systematic review and meta-analytic exploration","volume":"81","author":"Landry","year":"2017","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"2025121400474244000_12.12.e062278.12","doi-asserted-by":"crossref","unstructured":"Faymonville ME , Fiore GD , Maquet P . Neural mechanisms of antinociceptive effects of hypnosis, 2000.","DOI":"10.1097\/00003643-200000002-00578"},{"key":"2025121400474244000_12.12.e062278.13","doi-asserted-by":"publisher","DOI":"10.1080\/00207149608416074"},{"key":"2025121400474244000_12.12.e062278.14","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(97)00122-X"},{"key":"2025121400474244000_12.12.e062278.15","article-title":"Hypnosis for pain management during labor and childbirth","volume":"5","author":"Madden","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"2025121400474244000_12.12.e062278.16","article-title":"Withdrawn: hypnosis for children undergoing dental treatment","volume":"6","author":"Al-Harasi","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"2025121400474244000_12.12.e062278.17","doi-asserted-by":"crossref","unstructured":"Uman LS , Birnie KA , Noel M , et al . Psychological interventions for needle-related procedural pain and distress in children and adolescents. Cochrane Database Syst Rev 2013;76.doi:10.1002\/14651858.CD005179.pub3","DOI":"10.1002\/14651858.CD005179.pub3"},{"key":"2025121400474244000_12.12.e062278.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02162-0"},{"key":"2025121400474244000_12.12.e062278.19","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0733-8627(05)70128-0","article-title":"The use of hypnosis in emergency medicine","volume":"18","author":"Peebles-Kleiger","year":"2000","journal-title":"Emerg Med Clin North Am"},{"key":"2025121400474244000_12.12.e062278.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.09.024"},{"key":"2025121400474244000_12.12.e062278.21","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/EJA.0b013e3283418fb0","article-title":"Quality of pain management in the emergency department: results of a multicentre prospective study","volume":"28","author":"Gu\u00e9ant","year":"2011","journal-title":"Eur J Anaesthesiol"},{"key":"2025121400474244000_12.12.e062278.22","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1177\/106002809703100917","article-title":"Acute pain management: operative or medical procedures and trauma","volume":"31","author":"Follin","year":"1997","journal-title":"Ann Pharmacother"},{"key":"2025121400474244000_12.12.e062278.23","doi-asserted-by":"publisher","DOI":"10.1080\/00207149708416112"},{"key":"2025121400474244000_12.12.e062278.24","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.psych.52.1.685"},{"key":"2025121400474244000_12.12.e062278.25","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.neubiorev.2019.02.013","article-title":"The effectiveness of hypnosis for pain relief: a systematic review and meta-analysis of 85 controlled experimental trials","volume":"99","author":"Thompson","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"key":"2025121400474244000_12.12.e062278.26","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.129.4.495"},{"key":"2025121400474244000_12.12.e062278.27","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1080\/00207140590927536","article-title":"Control conditions in hypnotic-analgesia clinical trials: challenges and recommendations","volume":"53","author":"Jensen","year":"2005","journal-title":"Int J Clin Exp Hypn"},{"key":"2025121400474244000_12.12.e062278.28","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1080\/00207144.2015.1099405","article-title":"Hypnosis for acute procedural pain: a critical review","volume":"64","author":"Kendrick","year":"2016","journal-title":"Int J Clin Exp Hypn"},{"key":"2025121400474244000_12.12.e062278.29","doi-asserted-by":"publisher","DOI":"10.1080\/00207140008410045"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2022-062278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T08:47:52Z","timestamp":1765702072000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2022-062278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":29,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,7]]},"published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1136\/bmjopen-2022-062278"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2022-062278","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}