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A total of 5694 pregnant women were screened, with 4862 (85.4%) eligible pregnant women recruited at baseline. We assessed anthropometry, Haemoglobin status, Oral Glucose Tolerance Test (OGTT), dietary practices, depressive symptoms using the Edinburgh Postnatal Depression Scale and social support in all women. Follow-up visits involved assessing anthropometry and the health profile of mothers and children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings to date<\/jats:title>\n                    <jats:p>Among 4862 eligible participants recruited, 3260 (67%) underwent OGTT, while 2962 participants completed OGTT (90.9%). During the pregnancy, 9.7% of women were obese (&gt;90th percentile of skinfold thickness), and 14.3% had gestational diabetesmellitus. Moreover, 6.2% and 16.8% of women had symptoms suggestive of depression during pregnancy and the immediate postnatal period, respectively. We found that 3.3% of children were small for gestational age, 10.8% were large for gestational age and 9.7% of children were obese at birth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Future plans<\/jats:title>\n                    <jats:p>We have completed recruitment and baseline data collection in 2019, and are conducting annual follow-ups until age 4 of the participant\u2019s children. For delineating causal pathways of childhood obesity, blood aliquots are stored in the biorepository. The study will inform policy formulation and community awareness in the prevention and control of non-communicable diseases and health promotion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-063794","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T14:07:01Z","timestamp":1663769221000},"page":"e063794","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Cohort profile: maternal antecedents of adiposity and studying the transgenerational role of hyperglycaemia and insulin (MAASTHI)"],"prefix":"10.1136","volume":"12","author":[{"given":"Eunice","family":"Lobo","sequence":"first","affiliation":[{"name":"Indian Institute of Public Health, Public Health Foundation, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamuna","family":"Ana","sequence":"additional","affiliation":[{"name":"Indian Institute of Public Health, Public Health Foundation, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Deepa","sequence":"additional","affiliation":[{"name":"Indian Institute of Public Health, Public Health Foundation, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prafulla","family":"Shriyan","sequence":"additional","affiliation":[{"name":"Indian Institute of Public Health, Public Health Foundation, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N D","family":"Sindhu","sequence":"additional","affiliation":[{"name":"Indian Institute of Public Health, Public Health Foundation, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maithili","family":"Karthik","sequence":"additional","affiliation":[{"name":"Indian Institute of Public Health, Public Health Foundation, Bangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Kinra","sequence":"additional","affiliation":[{"name":"Department of Non-Communicable Diseases Epidemiology, London School of Hygiene & Tropical Medicine, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G V S","family":"Murthy","sequence":"additional","affiliation":[{"name":"IIPH Hyderabad, Public Health Foundation, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4370-8933","authenticated-orcid":false,"given":"Giridhara R","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,9,21]]},"reference":[{"key":"2025121402424595000_12.9.e063794.1","unstructured":"Health of the Nation\u2019s States . 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