{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:40:16Z","timestamp":1791391216379,"version":"4.3.3"},"reference-count":21,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"unspecified","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Leenards Foundation","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"crossref","award":["407240_167133"],"award-info":[{"award-number":["407240_167133"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to explore the acceptance and opinions of general practitioners (GPs) on the use of procalcitonin point-of-care and lung ultrasonography for managing patients with lower respiratory tract infections in primary care. We suppose that there are several factors that can influence the physician\u2019s antibiotic prescribing decision, and the implementation of a new tool will only be possible when it can be inserted into the physician\u2019s daily practice, helping him\/her in the decision-making process.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Semistructured interviews; data analysis using the grounded theory method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Lausanne, Switzerland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>12 GPs who participated in the randomised clinical trial UltraPro, which evaluated the impact of the use of procalcitonin only or an algorithm combining procalcitonin and lung ultrasonography on antibiotic prescription.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>GPs had mostly positive attitudes towards the use of point-of-care procalcitonin in lower respiratory tract infections and uncertainties regarding the usefulness of ultrasonography. Physicians\u2019 prescribing decisions result from interactions between three kinds of TrustS (core category): \u2018self-confidence\u2019, \u2018trust in the results\u2019 and \u2018trust in the doctor\u2013patient relationship\u2019. Procalcitonin reinforced the three levels of trust, while ultrasonography only strengthened the physician\u2013patient relationship. To facilitate implementation of procalcitonin, physicians pointed out the need of coverage by insurance and of clear guidelines describing the targeted patient population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data show that there is a preference for the implementation of procalcitonin rather than lung ultrasonography for the management of patients with lower respiratory tract infections in primary care. Coverage by insurance plans and updated guidelines are prerequisite to the successful implementation of procalcitonin testing in primary care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration number<\/jats:title><jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial pre-results\" xlink:href=\"NCT03191071\">NCT03191071<\/jats:ext-link><\/jats:p><\/jats:sec>","DOI":"10.1136\/bmjopen-2022-063922","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T14:15:16Z","timestamp":1683814516000},"page":"e063922","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Exploration of the Acceptance of the Use of Procalcitonin Point-of-Care Testing and Lung Ultrasonography by General Practitioners to Decide on Antibiotic Prescriptions for Lower Respiratory Infections: A Qualitative Study"],"prefix":"10.1136","volume":"13","clinical-trial-number":[{"clinical-trial-number":"nct03191071","registry":"10.18810\/clinical-trials-gov","type":"preResults"}],"author":[{"given":"Daniel","family":"Geis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7407-4577","authenticated-orcid":false,"given":"Nina","family":"Canova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lo\u00efc","family":"Lhopitallier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kronenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Yves","family":"Meuwly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Senn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne","family":"Fasseur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9mie","family":"Boillat-Blanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"key":"2023060101553566000_13.5.e063922.1","unstructured":"Organisation Mondial de la Sant\u00e9 . Premier rapport de l\u2019OMS sur la r\u00e9sistance aux antibiotiques: une menace grave d\u2019ampleur mondiale. 2014. Available: https:\/\/www.who.int\/fr\/news\/item\/30-04-2014-who-s-first-global-report-on-antibiotic-resistance-reveals-serious-worldwide-threat-to-public-health"},{"key":"2023060101553566000_13.5.e063922.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30592-3"},{"key":"2023060101553566000_13.5.e063922.3","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.18.2000"},{"key":"2023060101553566000_13.5.e063922.4","unstructured":"Burkhardt O , Ewig S , Haagen U , et al . A simple procalcitonin-guided strategy results in safe reductions of antibiotic use in patients with symptoms of acute respiratory tract infections in primary care. Eur Respir J 2010;25. 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