{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:24:10Z","timestamp":1784021050073,"version":"3.55.0"},"reference-count":17,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"unspecified","delay-in-days":27,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871456"],"award-info":[{"award-number":["81871456"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,10,12]]},"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to investigate the seasonality of paediatric intussusception and the associations between meteorological factors and paediatric intussusception in Hangzhou, as well as aimed to compare the variance in sex and disease type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>An 8-year retrospective study was conducted from January 2014 to December 2021 in the Children\u2019s Hospital of Zhejiang University, Hangzhou, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>This was a single-centre retrospective study review of intussusception cases in a large Children\u2019s Hospital in Hangzhou.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>There were 17\u2009674 patients with intussusception in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A Spearman correlation analysis and Poisson regression analysis were used to determine the association between weekly intussusception cases and meteorological factors. The seasonality of paediatric intussusception was demonstrated via the t-test and visualised.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>In January, May and December, there were relatively more intussusception patients. In February, there was a trough in the number of intussusception patients. Both the Spearman correlation analysis and Poisson regression analysis proved that weekly intussusception cases had significant associations with temperature (\u03bb=\u22120.205, p&lt;0.01; \u03b2=\u22120.080, p&lt;0.01), feels-like temperature (\u03bb=\u22120.214, p&lt;0.01; \u03b2=\u22120.012, p&lt;0.01), dew (\u03bb=\u22120.249, p&lt;0.01; \u03b2=0.095, p&lt;0.01), humidity (\u03bb=\u22120.230, p&lt;0.01; \u03b2=\u22120.037, p&lt;0.01), precipitation (\u03bb=\u22120.148, p&lt;0.01; \u03b2=\u22120.001, p&lt;0.01), windspeed (\u03bb=\u22120.135, p&lt;0.01; \u03b2=0.005, p&lt;0.01), visibility (\u03bb=\u22120.206, p&lt;0.01; \u03b2=\u22120.066, p&lt;0.01), sea level pressure (\u03bb=0.171, p&lt;0.01; \u03b2=\u22120.004, p&lt;0.01) and a total of 20 of 25 dynamic meteorological factors (p&lt;0.05). These associations reflected gender differences but showed stronger associations in groups that were prone to recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Paediatric intussusception in Hangzhou showed a seasonal tendency. Additionally, intussusception was significantly associated with certain meteorological factors in all of the cases. These findings suggest that parents and paediatricians should be more vigilant about the occurrence of intussusception in children regarding seasonal change times and climate change times.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-064967","type":"journal-article","created":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T11:19:06Z","timestamp":1666955946000},"page":"e064967","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Association of meteorological factors with paediatric intussusception in Hangzhou: an 8-year retrospective cohort study"],"prefix":"10.1136","volume":"12","author":[{"given":"Yuqing","family":"Feng","sequence":"first","affiliation":[{"name":"Clinical Data Center, The Children\u2019s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haichun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Radiology Department, The Children\u2019s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Shu","sequence":"additional","affiliation":[{"name":"Heart Center, The Children\u2019s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6420-7719","authenticated-orcid":false,"given":"Haomin","family":"Li","sequence":"additional","affiliation":[{"name":"Clinical Data Center, The Children\u2019s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, 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surveillance over 7 years in India","volume":"11","author":"Das","year":"2021","journal-title":"BMJ Open"},{"key":"2025121402360105000_12.10.e064967.6","doi-asserted-by":"publisher","DOI":"10.1016\/S1875-9572(10)60055-1"},{"key":"2025121402360105000_12.10.e064967.7","doi-asserted-by":"crossref","first-page":"7775","DOI":"10.1016\/j.vaccine.2017.06.073","article-title":"Intussusception among children less than 2years of age: findings from pre-vaccine introduction surveillance in Pakistan","volume":"36","author":"Yousafzai","year":"2018","journal-title":"Vaccine"},{"key":"2025121402360105000_12.10.e064967.8","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31815bb6b1"},{"key":"2025121402360105000_12.10.e064967.9","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ajem.2020.11.012","article-title":"Association of air temperature with pediatric intussusception in northeastern China: a 10-year retrospective 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