{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:16:06Z","timestamp":1779884166302,"version":"3.53.1"},"reference-count":11,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T00:00:00Z","timestamp":1693267200000},"content-version":"unspecified","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000664","name":"Health Technology Assessment Programme","doi-asserted-by":"publisher","award":["12\/127\/157"],"award-info":[{"award-number":["12\/127\/157"]}],"id":[{"id":"10.13039\/501100000664","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,4,28]]},"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To elicit and value patient preferences for the processes and outcomes of surgical management of stress urinary incontinence in women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A discrete choice experiment survey to elicit preferences for type of anaesthesia, postoperative recovery time, treatment success, adverse events, impact on daily activities and cost. An experimental design generated 40 choice tasks, and each respondent completed 1 block of 10 and 2 validity tests. Analysis was by multinomial logistical regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>N=21 UK hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>N=325 adult women who were a subsample of those randomised to the single-incision mini-slings clinical trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>Patient preferences; valuation obtained using willingness to pay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>N=227 of 325 (70%) returned a questionnaire, and 94% of those completed all choice tasks. Respondents preferred general anaesthesia, shorter recovery times, improved stress urinary incontinence symptoms and avoidance of adverse events. Women were willing to pay (mean (95% CI)) \u00a376 (\u00a333 to \u00a3119) per day of reduction in recovery time following surgery. They valued increases in Patient Global Impression of Improvement, ranging from \u00a38173 (\u00a35459 to \u00a310 887) for \u2018improved\u2019 to \u00a311 706 (\u00a38267 to \u00a315 144) for \u2018very much improved\u2019 symptoms, compared with no symptom improvement. This was offset by negative values attached to the avoidance of complications ranging between \u00a3\u22128022 (\u00a3\u221210 661 to \u00a3\u22125383) and \u00a3\u221210 632 (\u00a3\u221214 077 to \u00a3\u22127187) compared to no complications. Women valued treatments that reduced the need to avoid daily activities, with willingness to pay ranging from \u00a3\u2212967 (\u00a3\u22122199 to \u00a3266) for rarely avoiding activities to \u00a3\u22125338 (\u00a3\u22127258 to \u00a3\u22123417) for frequently avoiding daily activities compared with no avoidance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This discrete choice experiment demonstrates that patients place considerable value on improvement in stress urinary incontinence symptoms and avoidance of treatment complications. Trade-offs between symptom improvement and adverse event risk should be considered within shared decision-making. The willingness to pay values from this study can be used in future cost\u2013benefit analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>ISRCTN: 93264234; Post-results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-066157","type":"journal-article","created":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T13:00:29Z","timestamp":1693314029000},"page":"e066157","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Patient preferences for stress urinary incontinence treatments: a discrete choice experiment"],"prefix":"10.1136","volume":"13","clinical-trial-number":[{"clinical-trial-number":"isrctn93264234","registry":"10.18810\/isrctn"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9786-8118","authenticated-orcid":false,"given":"Dwayne","family":"Boyers","sequence":"first","affiliation":[{"name":"Health Economics Research Unit, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Kilonzo","sequence":"additional","affiliation":[{"name":"Health Economics Research Unit, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey","family":"Davidson","sequence":"additional","affiliation":[{"name":"Health Services Research Unit, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Cooper","sequence":"additional","affiliation":[{"name":"Health Services Research Unit, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Wardle","sequence":"additional","affiliation":[{"name":"Patient and Public Lead, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiron","family":"Bhal","sequence":"additional","affiliation":[{"name":"University Hospital of Wales, Cardiff, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"N'Dow","sequence":"additional","affiliation":[{"name":"Academic Urology Unit, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1039-5646","authenticated-orcid":false,"given":"Graeme","family":"MacLennan","sequence":"additional","affiliation":[{"name":"Health Services Research Unit, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9823-9252","authenticated-orcid":false,"given":"John","family":"Norrie","sequence":"additional","affiliation":[{"name":"Usher Institute, Edinburgh Clinical Trials Unit, University of Edinburgh No 9 Bioquarter, Edinburgh, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Abdel-Fattah","sequence":"additional","affiliation":[{"name":"Aberdeen Centre for Women's Health Research, University of Aberdeen, Aberdeen, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,8,29]]},"reference":[{"key":"2025120519051101000_13.8.e066157.1","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJMoa2111815","article-title":"Single incision mini slings for stress urinary incontinence in women","volume":"386","author":"Abdel-Fattah","year":"2022","journal-title":"N Engl J Med"},{"key":"2025120519051101000_13.8.e066157.2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.12195"},{"key":"2025120519051101000_13.8.e066157.3","doi-asserted-by":"crossref","unstructured":"Ryan M , Gerard K , Amaya-Amaya M . Using discrete choice experiments to value health and health care. Dordrecht: Springer Science & Business Media, 2008. doi:10.1007\/978-1-4020-5753-3","DOI":"10.1007\/978-1-4020-5753-3"},{"key":"2025120519051101000_13.8.e066157.4","doi-asserted-by":"publisher","DOI":"10.1086\/259131"},{"key":"2025120519051101000_13.8.e066157.5","unstructured":"McIntosh E , Clarke P , Frew E , et al . Applied methods of cost-benefit analysis in health care. Oxford University Press, 2010."},{"key":"2025120519051101000_13.8.e066157.6","unstructured":"Choice Metrics . NGENE user guide and reference manual. 2014. Available: http:\/\/www.choice-metrics.com\/NgeneManual120.pdf"},{"key":"2025120519051101000_13.8.e066157.7","unstructured":"Johnson R , Orme B . Sample size issues for conjoint analysis. In: Orme B , ed. Getting started with conjoint analysis: strategies for product design and pricing research. Madison: Research Publishers, 2010: 57\u201366."},{"key":"2025120519051101000_13.8.e066157.8","unstructured":"McFadden D . Conditional Logit analysis of qualitative choice behaviour. In: Zarembka P , ed. Frontiers in econometrics. New York: Academic Press, 1973: 105\u201342."},{"key":"2025120519051101000_13.8.e066157.9","doi-asserted-by":"publisher","DOI":"10.1002\/1099-1255(200009\/10)15:5<447::AID-JAE570>3.0.CO;2-1"},{"key":"2025120519051101000_13.8.e066157.10","doi-asserted-by":"publisher","DOI":"10.3310\/hta23010"},{"key":"2025120519051101000_13.8.e066157.11","doi-asserted-by":"crossref","DOI":"10.1097\/01.AOG.0000206213.48334.09","article-title":"Diagnostic aspects of incontinence study (Daisy) group. the \"costs\" of urinary Incontinence for women","volume":"107","author":"Subak","year":"2006","journal-title":"Obstet Gynaecol"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2022-066157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T03:05:21Z","timestamp":1764990321000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2022-066157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8,29]]},"published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1136\/bmjopen-2022-066157"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2022-066157","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8]]}}}