{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:54:55Z","timestamp":1793505295669,"version":"4.5.0"},"reference-count":56,"publisher":"BMJ","issue":"11","license":[{"start":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T00:00:00Z","timestamp":1667779200000},"content-version":"unspecified","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014438","name":"Business Finland","doi-asserted-by":"publisher","award":["860\/31\/2018 (eMOM GDM)"],"award-info":[{"award-number":["860\/31\/2018 (eMOM GDM)"]}],"id":[{"id":"10.13039\/501100014438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,10,18]]},"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Gestational diabetes (GDM) causes various adverse short-term and long-term consequences for the mother and child, and its incidence is increasing globally. So far, the most promising digital health interventions for GDM management have involved healthcare professionals to provide guidance and feedback. The principal aim of this study is to evaluate the effects of comprehensive and real-time self-tracking with eMOM GDM mobile application (app) on glucose levels in women with GDM, and more broadly, on different other maternal and neonatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This randomised controlled trial is carried out in Helsinki metropolitan area. We randomise 200 pregnant women with GDM into the intervention and the control group at gestational week (GW) 24\u201328 (baseline, BL). The intervention group receives standard antenatal care and the eMOM GDM app, while the control group will receive only standard care. Participants in the intervention group use the eMOM GDM app with continuous glucose metre (CGM) and activity bracelet for 1\u2009week every month until delivery and an electronic 3-day food record every month until delivery. The follow-up visit after intervention takes place 3 months post partum for both groups. Data are collected by laboratory blood tests, clinical measurements, capillary glucose measures, wearable sensors, air displacement plethysmography and digital questionnaires. The primary outcome is fasting plasma glucose change from BL to GW 35\u201337. Secondary outcomes include, for example, self-tracked capillary fasting and postprandial glucose measures, change in gestational weight gain, change in nutrition quality, change in physical activity, medication use due to GDM, birth weight and fat percentage of the child.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study has been approved by Ethics Committee of the Helsinki and Uusimaa Hospital District. The results will be presented in peer-reviewed journals and at conferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04714762\">NCT04714762<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-066292","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T09:33:20Z","timestamp":1667813600000},"page":"e066292","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Comprehensive self-tracking of blood glucose and lifestyle with a mobile application in the management of gestational diabetes: a study protocol for a randomised controlled trial (eMOM GDM study)"],"prefix":"10.1136","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct04714762","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4936-3502","authenticated-orcid":false,"given":"Mikko","family":"Kyt\u00f6","sequence":"first","affiliation":[{"name":"Department of IT Management, Helsinki University Hospital, Helsinki, Finland"},{"name":"Department of Computer Science, University of Helsinki, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9337-1198","authenticated-orcid":false,"given":"Lisa Torsdatter","family":"Markussen","sequence":"additional","affiliation":[{"name":"Department of IT Management, Helsinki University Hospital, Helsinki, Finland"},{"name":"Department of Food and Nutrition, University of Helsinki, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pekka","family":"Marttinen","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Aalto University, Aalto, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Jacucci","sequence":"additional","affiliation":[{"name":"Department of Computer Science, University of Helsinki, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari","family":"Niinist\u00f6","sequence":"additional","affiliation":[{"name":"Department of Public Health, Welfare Finnish Institute for Health and Welfare, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvi M","family":"Virtanen","sequence":"additional","affiliation":[{"name":"Department of Public Health and Welfare, The National Institute for Health and Welfare, Helsinki, Finland"},{"name":"Faculty of Social Sciences, Unit of Health Sciences, University of Tampere, Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuuli E","family":"Korhonen","sequence":"additional","affiliation":[{"name":"Department of Public Health, Welfare Finnish Institute for Health and Welfare, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harri","family":"Siev\u00e4nen","sequence":"additional","affiliation":[{"name":"UKK Institute for Health Promotion Research, Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"V\u00e4h\u00e4-Ypy\u00e4","sequence":"additional","affiliation":[{"name":"UKK Institute for Health Promotion Research, Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkka","family":"Korhonen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seppo","family":"Heinonen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saila B","family":"Koivusalo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland"},{"name":"Department of Obstetrics and Gynecology, Turku University Hospital, Turku, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,11,7]]},"reference":[{"key":"2025121605452803000_12.11.e066292.1","unstructured":"World Health Organization . 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