{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T14:49:17Z","timestamp":1783003757613,"version":"3.54.5"},"reference-count":29,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"unspecified","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"French Society for Hospital Hygiene","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]},{"DOI":"10.13039\/501100004571","name":"Minist\u00e8re des Affaires Sociales et de la Sant\u00e9","doi-asserted-by":"publisher","award":["PHRIP-18-0705"],"award-info":[{"award-number":["PHRIP-18-0705"]}],"id":[{"id":"10.13039\/501100004571","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,7,4]]},"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The midline catheter (MC) is an increasingly popular device used commonly for patients with difficult venous access or those who require infusion for more than 6\u2009days. Little is known about complications such as infection, thrombosis or occlusion for inpatient and home care patient. This protocol presents the follow-up of non-intensive care unit patients with an MC. The aim is to identify complications and search for risk factors associated with these complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method and analysis<\/jats:title>\n                    <jats:p>A prospective observational design is used for the follow-up of 2000 patients from 13 centres in France. Each practitioner (inserting clinician, anaesthetist nurse, hospital nurse and home nurse) will fill out a logbook to report each care made (eg, number of saline flushes, dress maintenance) on the MC and if any complications occurred. The incidence of complications (ie, infections, thrombosis or occlusions) will be expressed by the total number of events per 1000 catheter days. The period of recruitment began in December 2019 for a duration of 2 years. An extension of the inclusion period of 1\u2009year was obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>\n                      This study received the approval of the Committee for the Protection of Persons of Nord Ouest IV (No EudraCT\/ID-RCB : 2019-A02406-51). It was registered at clinical trials (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04131088\">NCT04131088<\/jats:ext-link>\n                      ). It is planned to communicate results at conferences and in a peer-reviewed journal.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04131088\">NCT04131088<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-067796","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T22:04:03Z","timestamp":1689717843000},"page":"e067796","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Complications and risk factors on midline catheters\u2019 follow-up about non-ICU patients: study protocol for a multicentre observational study (the midDATA study)"],"prefix":"10.1136","volume":"13","clinical-trial-number":[{"clinical-trial-number":"nct04131088","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04131088","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04131088","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1345-6889","authenticated-orcid":false,"given":"Yvan","family":"Derouin","sequence":"first","affiliation":[{"name":"P\u00f4le Anesth\u00e9sie-R\u00e9animation, Service d\u2019Anesth\u00e9sie R\u00e9animation Chirurgicale, Unit\u00e9 d\u2019acc\u00e8s vasculaires (UnAV), H\u00f4tel Dieu, Centre Hospitalier Universitaire de Nantes, Nantes, France"},{"name":"Nantes Universit\u00e9, Universit\u00e9 de Tours, CHU Nantes, INSERM UMR 1246 Methods in Patients-Centered Outcomes and Health Research, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Le Thuaut","sequence":"additional","affiliation":[{"name":"Direction de la Recherche, Plateforme de M\u00e9thodologie et Biostatistique, Centre Hospitalier Universitaire de Nantes, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9687-1059","authenticated-orcid":false,"given":"J\u00e9rome","family":"Dauvergne","sequence":"additional","affiliation":[{"name":"Service d'Anesth\u00e9sie-R\u00e9animation, h\u00f4pital La\u00ebnnec, Centre Hospitalier Universitaire de Nantes, Nantes, France"},{"name":"Pole hospitalo-universitaire 2 Institut du thorax et du systeme nerveux, Centre Hospitalier Universitaire de Nantes, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9217-8532","authenticated-orcid":false,"given":"Rapha\u00ebl","family":"Cinotti","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, Universit\u00e9 de Tours, CHU Nantes, INSERM UMR 1246 Methods in Patients-Centered Outcomes and Health Research, Nantes, France"},{"name":"P\u00f4le Anesth\u00e9sie-R\u00e9animation, Service d\u2019Anesth\u00e9sie R\u00e9animation Chirurgicale, H\u00f4tel Dieu, Centre Hospitalier Universitaire de Nantes, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Cartron","sequence":"additional","affiliation":[{"name":"D\u00e9partement universitaire des sciences infirmi\u00e8res de l'Universit\u00e9 de Paris Cit\u00e9, Universit\u00e9 de Paris, Paris, France"},{"name":"ECEVE - UMR-S 1123, Universit\u00e9 de Paris Facult\u00e9 de Sant\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,7,18]]},"reference":[{"key":"2025121514203223000_13.7.e067796.1","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1177\/1129729820907250","article-title":"Ultrasound-guided tip location of midline 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