{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:32:23Z","timestamp":1791495143349,"version":"4.3.4"},"reference-count":35,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"unspecified","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Yunnan Medical Leading Talents Training Program","award":["L-201619"],"award-info":[{"award-number":["L-201619"]}]},{"DOI":"10.13039\/501100005891","name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]},{"name":"\u201cTen Thousand Plan\u201d Industrial Technology Leading Talents Funding Project","award":["YNWR-CYJS-2019-036"],"award-info":[{"award-number":["YNWR-CYJS-2019-036"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,2,16]]},"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Breast milk is recognised as the best natural food for neonates, but many women experience postpartum hypogalactia (PH). Randomised trials have found that acupuncture exert therapeutic effect on women with PH. However, systematic reviews on the efficacy and safety of acupuncture are still lacking; therefore, this systematic review aims to evaluate the efficacy and safety of acupuncture for PH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>Six English databases (PubMed, Cochrane Library, EMBASE, EBSCO, Scopus, and Web of Science) and four Chinese databases (China National Knowledge Infrastructure, Wan-Fang, Chinese Biomedical Literature and Chinese Scientific Journal) will be systematically searched from their establishment to 1 September 2022. Randomised controlled trials of the efficacy of acupuncture for PH will be reviewed. The study selection, data extraction and research quality evaluation will be conducted independently by two reviewers. The primary outcome is the change in serum prolactin level from baseline to the end of treatment. Secondary results include milk secretion volume, total effectiveness rate, degree of mammary fullness, rate of exclusive breast feeding, and adverse events. A meta-analysis will be performed using RevMan V.5.4 statistical software. Otherwise, a descriptive analysis will be conducted. The risk of bias will be assessed using the revised Cochrane risk-of-bias tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This systematic review protocol does not require ethical approval because it does not include private information\/data of the participants. This article will be published in peer-reviewed journals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42022351849.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2022-068224","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T11:07:12Z","timestamp":1678360032000},"page":"e068224","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy and safety of acupuncture for postpartum hypogalactia: protocol for a systematic review and meta-analysis"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2350-5381","authenticated-orcid":false,"given":"Qiong-Nan","family":"Bao","sequence":"first","affiliation":[{"name":"School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China"},{"name":"Department of Traditional Chinese Medicine, The First People's Hospital of Yunnan Province; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China"},{"name":"Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5848-6432","authenticated-orcid":false,"given":"Yuan-Fang","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China"},{"name":"Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1543-0551","authenticated-orcid":false,"given":"Zi-Han","family":"Yin","sequence":"additional","affiliation":[{"name":"School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China"},{"name":"Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu","family":"Bi","sequence":"additional","affiliation":[{"name":"The First People's Hospital of Yunnan Province; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Bin","family":"Zhao","sequence":"additional","affiliation":[{"name":"The First People's Hospital of Yunnan Province; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Yong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, The First People's Hospital of Yunnan Province; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8518-9268","authenticated-orcid":false,"given":"Fan-Rong","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China"},{"name":"Sichuan Provincial Acupuncture Clinical Medicine Research Center, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"2025101811262564000_13.3.e068224.1","unstructured":"World Health Organization . 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