{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T20:14:30Z","timestamp":1780517670361,"version":"3.54.1"},"reference-count":38,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"unspecified","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"NIHR","doi-asserted-by":"crossref","award":["NIHR202743"],"award-info":[{"award-number":["NIHR202743"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Functional cognitive disorder (FCD) is seen increasingly in clinics commissioned to assess cognitive disorders. Patients report frequent cognitive, especially memory, failures. The diagnosis can be made clinically, and unnecessary investigations avoided. While there is some evidence that psychological treatments can be helpful, they are not routinely available. Therefore, we have developed a brief psychological intervention using the principles of acceptance and commitment therapy (ACT) that can be delivered in groups and online. We are conducting a feasibility study to assess whether the intervention can be delivered within a randomised controlled trial. We aim to study the feasibility of recruitment, willingness to be randomised to intervention or control condition, adherence to the intervention, completion of outcome measures and acceptability of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>We aim to recruit 48 participants randomised 50:50 to either the ACT intervention and treatment as usual (TAU), or TAU alone. ACT will be provided to participants in the treatment arm following completion of baseline outcome measures. Completion of these outcome measures will be repeated at 8, 16 and 26 weeks. The measures will assess several domains including psychological flexibility, subjective cognitive symptoms, mood and anxiety, health-related quality of life and functioning, healthcare utilisation, and satisfaction with care and participant-rated improvement. Fifteen participants will be selected for in-depth qualitative interviews about their experiences of living with FCD and of the ACT intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study received a favourable opinion from the South East Scotland Research Ethics Committee 02 on 30 September 2022 (REC reference: 22\/SS\/0059). HRA approval was received on 1 November 2022 (IRAS 313730). The results will be published in full in an open-access journal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"isrctn\" xlink:href=\"ISRCTN12939037\">ISRCTN12939037<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-072366","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T10:17:10Z","timestamp":1683800230000},"page":"e072366","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Feasibility randomised controlled trial of online group Acceptance and Commitment Therapy for Functional Cognitive Disorder (ACT4FCD)"],"prefix":"10.1136","volume":"13","clinical-trial-number":[{"clinical-trial-number":"isrctn12939037","registry":"10.18810\/isrctn"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3187-6430","authenticated-orcid":false,"given":"Norman","family":"Poole","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1672-9459","authenticated-orcid":false,"given":"Sarah","family":"Cope","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Vanzan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Duffus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0352-7444","authenticated-orcid":false,"given":"Nadia","family":"Mantovani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara M","family":"Barrett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Tokley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Scicluna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Beardmore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kati","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Howard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"key":"2023051107151908000_13.5.e072366.1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awaa224"},{"key":"2023051107151908000_13.5.e072366.2","doi-asserted-by":"publisher","DOI":"10.1192\/bja.2019.38"},{"key":"2023051107151908000_13.5.e072366.3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S2215-0366(19)30405-5","article-title":"Functional cognitive disorders: a systematic review","volume":"7","author":"McWhirter","year":"2020","journal-title":"Lancet Psychiatry"},{"key":"2023051107151908000_13.5.e072366.4","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-317823"},{"key":"2023051107151908000_13.5.e072366.5","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws129"},{"key":"2023051107151908000_13.5.e072366.6","doi-asserted-by":"crossref","first-page":"216","DOI":"10.7861\/clinmedicine.14-2-216","article-title":"Impact of the National dementia strategy in a neurology-led memory clinic: 5-year data","volume":"14","author":"Larner","year":"2014","journal-title":"Clin Med (Lond)"},{"key":"2023051107151908000_13.5.e072366.7","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e318187ddf9"},{"key":"2023051107151908000_13.5.e072366.8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38628.466898.55"},{"key":"2023051107151908000_13.5.e072366.9","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/psyg.12232","article-title":"How the UK describes functional memory symptoms","volume":"17","author":"Bailey","year":"2017","journal-title":"Psychogeriatrics"},{"key":"2023051107151908000_13.5.e072366.10","doi-asserted-by":"publisher","DOI":"10.1159\/000254901"},{"key":"2023051107151908000_13.5.e072366.11","doi-asserted-by":"crossref","unstructured":"Bhome R , Berry AJ , Huntley JD , et al . Interventions for subjective cognitive decline: systematic review and meta-analysis. BMJ Open 2018;8:e021610. doi:10.1136\/bmjopen-2018-021610","DOI":"10.1136\/bmjopen-2018-021610"},{"key":"2023051107151908000_13.5.e072366.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2005.06.006"},{"key":"2023051107151908000_13.5.e072366.13","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.yebeh.2017.06.003","article-title":"Treating functional non-epileptic attacks \u2013 should we consider acceptance and commitment therapy?","volume":"73","author":"Cope","year":"2017","journal-title":"Epilepsy & Behavior"},{"key":"2023051107151908000_13.5.e072366.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2005.06.006"},{"key":"2023051107151908000_13.5.e072366.15","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcbs.2014.06.003","article-title":"Examining psychological inflexibility as a transdiagnostic process across psychological disorders","volume":"3","author":"Levin","year":"2014","journal-title":"Journal of Contextual Behavioral Science"},{"key":"2023051107151908000_13.5.e072366.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2016.06.003"},{"key":"2023051107151908000_13.5.e072366.17","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jcbs.2020.09.009","article-title":"The empirical status of acceptance and commitment therapy: a review of meta-analyses","volume":"18","author":"Gloster","year":"2020","journal-title":"Journal of Contextual Behavioral Science"},{"key":"2023051107151908000_13.5.e072366.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2021.09.022"},{"key":"2023051107151908000_13.5.e072366.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2016.04.009"},{"key":"2023051107151908000_13.5.e072366.20","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/cpp.2174","article-title":"A case series of acceptance and commitment therapy (act) for reducing symptom interference in functional neurological disorders","volume":"25","author":"Graham","year":"2018","journal-title":"Clin Psychol Psychother"},{"key":"2023051107151908000_13.5.e072366.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2015.10.001"},{"key":"2023051107151908000_13.5.e072366.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.beth.2020.07.002"},{"key":"2023051107151908000_13.5.e072366.23","unstructured":"World Health Organisation . Measuring health and disability: manual for who disability assessment schedule (WHODAS 2.0). Geneva (CH): World Health Organization, 2010."},{"key":"2023051107151908000_13.5.e072366.24","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9903-x"},{"key":"2023051107151908000_13.5.e072366.25","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9927-2"},{"key":"2023051107151908000_13.5.e072366.26","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/57.1.P19"},{"key":"2023051107151908000_13.5.e072366.27","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"2023051107151908000_13.5.e072366.28","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"2023051107151908000_13.5.e072366.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.beth.2011.03.007"},{"key":"2023051107151908000_13.5.e072366.30","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0140-6736(13)61905-4","article-title":"Clinical and cost-effectiveness of cognitive behaviour therapy for health anxiety in medical patients: a multicentre randomised controlled trial","volume":"383","author":"Tyrer","year":"2014","journal-title":"The Lancet"},{"key":"2023051107151908000_13.5.e072366.31","unstructured":"Guy W . Clinical global impressions (cGI) scale, modified. In: Rush JA , ed. Task Force for the Handbook of Psychiatric Measures (eds.). Handbook of Psychiatric Measures. 1st ed. Washington, DC: American Psychiatric Association, 2000."},{"key":"2023051107151908000_13.5.e072366.32","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2013.02.010"},{"key":"2023051107151908000_13.5.e072366.33","doi-asserted-by":"publisher","DOI":"10.1002\/pst.185"},{"key":"2023051107151908000_13.5.e072366.34","doi-asserted-by":"publisher","DOI":"10.1111\/j..2002.384.doc.x"},{"key":"2023051107151908000_13.5.e072366.35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2011.07.011"},{"key":"2023051107151908000_13.5.e072366.36","doi-asserted-by":"crossref","unstructured":"Eldridge SM , Chan CL , Campbell MJ , et al . n.d. Consort 2010 statement: extension to randomised pilot and feasibility trials. BMJ:i5239. doi:10.1136\/bmj.i5239","DOI":"10.1136\/bmj.i5239"},{"key":"2023051107151908000_13.5.e072366.37","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsp004"},{"key":"2023051107151908000_13.5.e072366.38","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"Braun","year":"2006","journal-title":"Qualitative Research in Psychology"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-072366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T10:17:27Z","timestamp":1683800247000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-072366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":38,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5,11]]},"published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1136\/bmjopen-2023-072366"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-072366","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.02.20.23286183","asserted-by":"object"}]},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]}}}