{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T12:14:13Z","timestamp":1785500053460,"version":"3.56.0"},"reference-count":92,"publisher":"BMJ","issue":"4","license":[{"start":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T00:00:00Z","timestamp":1681344000000},"content-version":"unspecified","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Canadian Health Research Institute","award":["202203PJT-480065-CHI-CFAC-168509"],"award-info":[{"award-number":["202203PJT-480065-CHI-CFAC-168509"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,3,20]]},"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Therapeutic hypothermia (TH) became the standard of care treatment for neonates with moderate and severe neonatal encephalopathy (NE) in most industrialized countries about 10 years ago. Although TH is effective in reducing mortality and the incidence of severe developmental disabilities, the recent literature converges in reporting frequent cognitive and behavioural difficulties at school entry in children with NE-TH. Although these challenges are deemed minor compared with cerebral palsy and intellectual disability, their impacts on a child\u2019s self-determination and family\u2019s well-being are quite significant. Therefore, the nature and extent of these difficulties need to be comprehensively described so that appropriate care can be offered.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>The current study will be the largest follow-up study of neonates with NE treated with TH to characterize their developmental outcomes and associated brain structural profiles at 9 years of age. Specifically, we will compare executive function, attention, social cognition, behaviour, anxiety, self-esteem, peer problems, brain volume, cortical features, white matter microstructure and myelination between children with NE-TH and matched peers without NE. Associations of perinatal risk factors and structural brain integrity with cognitive, behavioural and psycho-emotional deficits will be evaluated to inform about the potential aggravating and protective factors associated with function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This study is supported by the Canadian Institute of Health Research (202203PJT-480065-CHI-CFAC-168509), and received approval from the Pediatric Ethical Review Board of the McGill University Health Center (MP-37-2023-9320). The study findings will be disseminated in scientific journals and conferences and presented to parental associations and healthcare providers to inform best practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial pre-results\" xlink:href=\"NCT05756296\">NCT05756296<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-073063","type":"journal-article","created":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T14:13:10Z","timestamp":1681395190000},"page":"e073063","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Long-term consequences of neonatal encephalopathy in the hypothermia era: protocol for a follow-up cohort study at 9 years of age"],"prefix":"10.1136","volume":"13","clinical-trial-number":[{"clinical-trial-number":"nct05756296","registry":"10.18810\/clinical-trials-gov","type":"preResults"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0641-0054","authenticated-orcid":false,"given":"Marie","family":"Brossard-Racine","sequence":"first","affiliation":[{"name":"Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada"},{"name":"School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanouille","family":"Rampakakis","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine Lucas","family":"Tardif","sequence":"additional","affiliation":[{"name":"Montreal Neurological Institute-Hospital, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Gilbert","sequence":"additional","affiliation":[{"name":"MR Clinical Science, Philips Canada, Mississauga, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"White","sequence":"additional","affiliation":[{"name":"Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuy Mai","family":"Luu","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada"},{"name":"University of Montreal, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada"},{"name":"University of Montreal, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elana","family":"Pinchefsky","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada"},{"name":"University of Montreal, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Montreuil","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, McGill University Montreal, Montreal, Quebec, Canada"},{"name":"Department of Educational and Counselling Psychology, McGill University Montreal, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Noelle","family":"Simard","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada"},{"name":"University of Montreal, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Wintermark","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"key":"2025121422425794000_13.4.e073063.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2579"},{"key":"2025121422425794000_13.4.e073063.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.01.029"},{"key":"2025121422425794000_13.4.e073063.3","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2004.10.003"},{"key":"2025121422425794000_13.4.e073063.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2008.07.010"},{"key":"2025121422425794000_13.4.e073063.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcps050929"},{"key":"2025121422425794000_13.4.e073063.6","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1053\/j.semperi.2016.09.007","article-title":"Outcomes in childhood following therapeutic hypothermia for neonatal Hypoxic-Ischemic Encephalopathy (HIE)","volume":"40","author":"Natarajan","year":"2016","journal-title":"Semin Perinatol"},{"key":"2025121422425794000_13.4.e073063.7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0900854"},{"key":"2025121422425794000_13.4.e073063.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60837-5"},{"key":"2025121422425794000_13.4.e073063.9","article-title":"Cooling for newborns with hypoxic ischaemic encephalopathy","volume":"2013","author":"Jacobs","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"2025121422425794000_13.4.e073063.10","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-019-0551-2"},{"key":"2025121422425794000_13.4.e073063.11","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3233\/NPM-190368","article-title":"Neonates with hypoxic-ischemic encephalopathy treated with hypothermia: observations in a large Canadian population and determinants of death and\/or brain injury","volume":"13","author":"Xu","year":"2020","journal-title":"J Neonatal Perinatal Med"},{"key":"2025121422425794000_13.4.e073063.12","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.ejpn.2018.01.017","article-title":"Prediction of outcome in asphyxiated newborns treated with hypothermia: is a MRI scoring system described before the cooling era still useful?","volume":"22","author":"Al Amrani","year":"2018","journal-title":"Eur J Paediatr Neurol"},{"key":"2025121422425794000_13.4.e073063.13","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306550"},{"key":"2025121422425794000_13.4.e073063.14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315788"},{"key":"2025121422425794000_13.4.e073063.15","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.184291"},{"key":"2025121422425794000_13.4.e073063.16","first-page":"143","article-title":"Prediction of neuromotor outcome in perinatal asphyxia: evaluation of Mr scoring systems","volume":"19","author":"Barkovich","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025121422425794000_13.4.e073063.17","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jpeds.2020.11.015","article-title":"Limitations of conventional magnetic resonance imaging as a predictor of death or disability following neonatal hypoxic-ischemic encephalopathy in the late hypothermia trial","volume":"230","author":"Laptook","year":"2021","journal-title":"J Pediatr"},{"key":"2025121422425794000_13.4.e073063.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.12.026"},{"key":"2025121422425794000_13.4.e073063.19","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.pediatrneurol.2017.04.025","article-title":"Early imaging and adverse neurodevelopmental outcome in asphyxiated newborns treated with hypothermia","volume":"73","author":"Al Amrani","year":"2017","journal-title":"Pediatr Neurol"},{"key":"2025121422425794000_13.4.e073063.20","doi-asserted-by":"crossref","first-page":"653727","DOI":"10.1155\/2015\/653727","article-title":"Evolution of apparent diffusion coefficient and fractional anisotropy in the cerebrum of asphyxiated newborns treated with hypothermia over the first month of life","volume":"2015","author":"Kwan","year":"2015","journal-title":"Neural Plast"},{"key":"2025121422425794000_13.4.e073063.21","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.nicl.2014.08.010","article-title":"Measurement of brain perfusion in newborns: pulsed arterial spin labeling (PASL) versus pseudo-continuous arterial spin labeling (pCASL)","volume":"6","author":"Boudes","year":"2014","journal-title":"Neuroimage Clin"},{"key":"2025121422425794000_13.4.e073063.22","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2708"},{"key":"2025121422425794000_13.4.e073063.23","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21525"},{"key":"2025121422425794000_13.4.e073063.24","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21379"},{"key":"2025121422425794000_13.4.e073063.25","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5350"},{"key":"2025121422425794000_13.4.e073063.26","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4326"},{"key":"2025121422425794000_13.4.e073063.27","unstructured":"Malalourf G , Al Amrani F , Marcelis T , et al . Brain growth is already impaired during the first month of life in asphyxiated newborns developing later adverse outcome. Baltimore, MD: Pediatric Academic Societies, 2019."},{"key":"2025121422425794000_13.4.e073063.28","unstructured":"Marcelis T , Kwan S , Oliveri B , et al . Is brain growth altered in asphyxiated newborns developing brain injury despite hypothermia treatment? Montreal, PQ: 2nd Congres Provincial Mere-Enfant, 2018."},{"key":"2025121422425794000_13.4.e073063.29","doi-asserted-by":"crossref","first-page":"102678","DOI":"10.1016\/j.nicl.2021.102678","article-title":"Myelination may be impaired in neonates following birth asphyxia","volume":"31","author":"Olivieri","year":"2021","journal-title":"Neuroimage Clin"},{"key":"2025121422425794000_13.4.e073063.30","doi-asserted-by":"crossref","first-page":"102582","DOI":"10.1016\/j.nicl.2021.102582","article-title":"Disrupted brain connectivity in children treated with therapeutic hypothermia for neonatal encephalopathy","volume":"30","author":"Spencer","year":"2021","journal-title":"Neuroimage Clin"},{"key":"2025121422425794000_13.4.e073063.31","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(89)80132-5"},{"key":"2025121422425794000_13.4.e073063.32","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/00004703-198810000-00009","article-title":"Educational readiness of survivors of neonatal encephalopathy associated with birth asphyxia at term","volume":"9","author":"Robertson","year":"1988","journal-title":"J Dev Behav Pediatr"},{"key":"2025121422425794000_13.4.e073063.33","doi-asserted-by":"publisher","DOI":"10.1136\/fn.86.1.F16"},{"key":"2025121422425794000_13.4.e073063.34","doi-asserted-by":"publisher","DOI":"10.1080\/87565641.2011.581320"},{"key":"2025121422425794000_13.4.e073063.35","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsp049"},{"key":"2025121422425794000_13.4.e073063.36","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1298"},{"key":"2025121422425794000_13.4.e073063.37","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2011.30"},{"key":"2025121422425794000_13.4.e073063.38","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112066"},{"key":"2025121422425794000_13.4.e073063.39","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1080\/13854046.2020.1833987","article-title":"Towards a biopsychosocial understanding of neurodevelopmental outcomes in children with hypoxic-ischemic encephalopathy: a mixed-methods study","volume":"35","author":"Danguecan","year":"2021","journal-title":"Clin Neuropsychol"},{"key":"2025121422425794000_13.4.e073063.40","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/cd.302","article-title":"Self-regulation and academic achievement in elementary school children","volume":"2011","author":"McClelland","year":"2011","journal-title":"New Dir Child Adolesc Dev"},{"key":"2025121422425794000_13.4.e073063.41","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1412.011"},{"key":"2025121422425794000_13.4.e073063.42","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2010.09.2200"},{"key":"2025121422425794000_13.4.e073063.43","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2318-10-16","article-title":"The independent contribution of executive functions to health related quality of life in older women","volume":"10","author":"Davis","year":"2010","journal-title":"BMC Geriatr"},{"key":"2025121422425794000_13.4.e073063.44","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.43.6.1428"},{"key":"2025121422425794000_13.4.e073063.45","article-title":"Long-term outcomes after neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia: a longitudinal, prospective, multicenter case-control study in children without overt brain damage","volume":"8","author":"Cainelli","year":"2021","journal-title":"Children (Basel)"},{"key":"2025121422425794000_13.4.e073063.46","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1111\/apa.16002","article-title":"Children with neonatal Hypoxic Ischaemic Encephalopathy (HIE) treated with therapeutic hypothermia are not as school ready as their Peers","volume":"110","author":"Edmonds","year":"2021","journal-title":"Acta Paediatr"},{"key":"2025121422425794000_13.4.e073063.47","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2018-316509"},{"key":"2025121422425794000_13.4.e073063.48","doi-asserted-by":"publisher","DOI":"10.1080\/02699052.2019.1597163"},{"key":"2025121422425794000_13.4.e073063.49","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejpn.2021.10.005","article-title":"Neonatal hypoxic-ischaemic encephalopathy: motor impairment beyond cerebral palsy","volume":"35","author":"Erdi-Krausz","year":"2021","journal-title":"Eur J Paediatr Neurol"},{"key":"2025121422425794000_13.4.e073063.50","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1111\/apa.14780","article-title":"Motor performance and cognitive correlates in children cooled for neonatal encephalopathy without cerebral palsy at school age","volume":"108","author":"Jary","year":"2019","journal-title":"Acta Paediatr"},{"key":"2025121422425794000_13.4.e073063.51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2011.10.001"},{"key":"2025121422425794000_13.4.e073063.52","doi-asserted-by":"publisher","DOI":"10.1177\/0883073812461942"},{"key":"2025121422425794000_13.4.e073063.53","doi-asserted-by":"crossref","first-page":"103934","DOI":"10.1016\/j.ridd.2021.103934","article-title":"WISC-V motor-free cognitive profile and predictive factors in adolescents with cerebral palsy","volume":"113","author":"Coceski","year":"2021","journal-title":"Res Dev Disabil"},{"key":"2025121422425794000_13.4.e073063.54","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1111\/apa.13146","article-title":"Less severe cerebral palsy outcomes in infants treated with therapeutic hypothermia","volume":"104","author":"Jary","year":"2015","journal-title":"Acta Paediatr"},{"key":"2025121422425794000_13.4.e073063.55","doi-asserted-by":"crossref","unstructured":"Levine DS . Neuroexecutive function. In: Encyclopedia of human behavior. 2012: 701\u20136.","DOI":"10.1016\/B978-0-12-375000-6.00162-2"},{"key":"2025121422425794000_13.4.e073063.56","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2017.00557","article-title":"The stroop color and word test","volume":"8","author":"Scarpina","year":"2017","journal-title":"Front Psychol"},{"key":"2025121422425794000_13.4.e073063.57","doi-asserted-by":"crossref","unstructured":"Deli DC , Kaplan E , Kramer JH . Delis-kaplan executive function system. Pearson Publication Inc, 2001.","DOI":"10.1037\/t15082-000"},{"key":"2025121422425794000_13.4.e073063.58","first-page":"215","article-title":"L\u2019examen psychologique dans les cas d\u2019enc\u00e9phalopathie traumatique. (Les problems.). [The psychological examination in cases of traumatic encepholopathy. Problems]","volume":"28","author":"Rey","year":"1941","journal-title":"Arch Psychol (Geneve)"},{"key":"2025121422425794000_13.4.e073063.59","unstructured":"Conners CK . Conner continuous performance test. 3rd ed. Pearson Publication Inc, 2014."},{"key":"2025121422425794000_13.4.e073063.60","doi-asserted-by":"crossref","unstructured":"Hunt C , Borgida E , Lavine H . Social cognition. In: Encyclopedia of Human Behavior. 2012: 456\u201362.","DOI":"10.1016\/B978-0-12-375000-6.00331-1"},{"key":"2025121422425794000_13.4.e073063.61","doi-asserted-by":"crossref","unstructured":"Korjman M , Kirk U , Kemp S . NEPSY second edition (NEPSY-II): A developmental neuropsychological assessment. Pearson Publication Inc, 2007.","DOI":"10.1037\/t15125-000"},{"key":"2025121422425794000_13.4.e073063.62","unstructured":"Flemmer DD , Roid GH . Leither internaltional performance scale - revised. Wod Dale, IL: Stoelting, 1997."},{"key":"2025121422425794000_13.4.e073063.63","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-016633","article-title":"Protocol for a prospective, school-based standardisation study of a digital social skills assessment tool for children: the paediatric evaluation of emotions, relationships, and socialisation (Peers) study","volume":"8","author":"Thompson","year":"2018","journal-title":"BMJ Open"},{"key":"2025121422425794000_13.4.e073063.64","unstructured":"Beck JS , Beck AT , Jolly JB . Beck youth inventories. 2nd ed. San Antonio, TX: Peason, 2005."},{"key":"2025121422425794000_13.4.e073063.65","doi-asserted-by":"crossref","unstructured":"Spence SH . Spence children\u2019s anxiety scale. Washington, DC: American Psychology Association, 1997.","DOI":"10.1037\/t10518-000"},{"key":"2025121422425794000_13.4.e073063.66","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199704000-00019"},{"key":"2025121422425794000_13.4.e073063.67","doi-asserted-by":"publisher","DOI":"10.1023\/B:JOBA.0000007455.08539.94"},{"key":"2025121422425794000_13.4.e073063.68","doi-asserted-by":"publisher","DOI":"10.1080\/01942630802574908"},{"key":"2025121422425794000_13.4.e073063.69","unstructured":"Russel DJ , Rosenbaum P , Wright M , et al . Gross motor function measure (GMFM-66 & GMFM-88) user\u2019s manual. 2nd ed. Mac Keith Press, 2013: 304."},{"key":"2025121422425794000_13.4.e073063.70","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1997.tb07414.x"},{"key":"2025121422425794000_13.4.e073063.71","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206001162"},{"key":"2025121422425794000_13.4.e073063.72","unstructured":"Berry KE , Buktenica NA , Berry NA . Berry-buktenica developmental test of visual motor. 6th ed. Pearson Publication Inc, 2010."},{"key":"2025121422425794000_13.4.e073063.73","unstructured":"Harrison P , Oakland T . Adaptive behavior assessment systems. 3rd ed. Pearson Publication Inc, 2015."},{"key":"2025121422425794000_13.4.e073063.74","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22092"},{"key":"2025121422425794000_13.4.e073063.75","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2014.04.054"},{"key":"2025121422425794000_13.4.e073063.76","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2000.0652"},{"key":"2025121422425794000_13.4.e073063.77","doi-asserted-by":"crossref","unstructured":"Radua J , Vieta E , Shinohara R , et al . Increased power by harmonizing structural MRI site differences with the combat batch adjustment method in enigma. Neuroimage 2020;218. doi:10.1016\/j.neuroimage.2020.116956","DOI":"10.1016\/j.neuroimage.2020.116956"},{"key":"2025121422425794000_13.4.e073063.78","doi-asserted-by":"crossref","unstructured":"Beer JC , Tustison NJ , Cook PA , et al . Longitudinal combat: a method for harmonizing longitudinal multi-scanner imaging data. Neuroimage 2020;220. doi:10.1016\/j.neuroimage.2020.117129","DOI":"10.1016\/j.neuroimage.2020.117129"},{"key":"2025121422425794000_13.4.e073063.79","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.03.072"},{"key":"2025121422425794000_13.4.e073063.80","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21732"},{"key":"2025121422425794000_13.4.e073063.81","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2013.00095","article-title":"Quantitative multi-parameter mapping of R1, PD (*), MT, and R2 (*) at 3T: a multi-center validation","volume":"7","author":"Weiskopf","year":"2013","journal-title":"Front Neurosci"},{"key":"2025121422425794000_13.4.e073063.82","doi-asserted-by":"crossref","unstructured":"Theaud G , Houde J-C , Bor\u00e9 A , et al . TractoFlow: a robust, efficient and reproducible diffusion MRI pipeline leveraging nextflow & singularity. Neuroimage 2020;218. doi:10.1016\/j.neuroimage.2020.116889","DOI":"10.1016\/j.neuroimage.2020.116889"},{"key":"2025121422425794000_13.4.e073063.83","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.nicl.2017.07.020","article-title":"A test-retest study on Parkinson\u2019s PPMI dataset yields statistically significant white matter fascicles","volume":"16","author":"Cousineau","year":"2017","journal-title":"Neuroimage Clin"},{"key":"2025121422425794000_13.4.e073063.84","doi-asserted-by":"crossref","unstructured":"Cruces RR , Royer J , Herholz P , et al . Micapipe: a pipeline for multimodal neuroimaging and connectome analysis. Neuroimage 2022;263. doi:10.1016\/j.neuroimage.2022.119612","DOI":"10.1016\/j.neuroimage.2022.119612"},{"key":"2025121422425794000_13.4.e073063.85","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.10.003"},{"key":"2025121422425794000_13.4.e073063.86","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2016.12.003"},{"key":"2025121422425794000_13.4.e073063.87","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1093\/cercor\/bhz279","article-title":"Sex-based differences in cortical and subcortical development in 436 individuals aged 4-54 years","volume":"30","author":"Duerden","year":"2020","journal-title":"Cereb Cortex"},{"key":"2025121422425794000_13.4.e073063.88","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2014.00276","article-title":"Socioeconomic status and structural brain development","volume":"8","author":"Brito","year":"2014","journal-title":"Front Neurosci"},{"key":"2025121422425794000_13.4.e073063.89","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2010.01.006"},{"key":"2025121422425794000_13.4.e073063.90","first-page":"364","article-title":"Association between primary caregiver education and cognitive and language development of preterm neonates","volume":"34","author":"Asztalos","year":"2017","journal-title":"Am J Perinatol"},{"key":"2025121422425794000_13.4.e073063.91","doi-asserted-by":"publisher","DOI":"10.1177\/10791102009002005"},{"key":"2025121422425794000_13.4.e073063.92","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-073063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T06:43:09Z","timestamp":1765780989000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-073063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":92,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4,13]]},"published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1136\/bmjopen-2023-073063"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-073063","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]}}}