{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T11:33:14Z","timestamp":1774870394330,"version":"3.50.1"},"reference-count":29,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"unspecified","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Today, the involvement of patients in their care is essential. As the population ages increases, the number of patients with chronic diseases is increasing. In the vascular medicine and surgery departments, patients are polymedicated and mostly suffer from several chronic diseases. Approximately 50% of patients with a chronic disease are not adherent. Among the factors that can influence therapeutic adherence are the beliefs and representations of patients.<\/jats:p><jats:p>To evaluate the beliefs and representations of chronic treatments in patients with multiple medications and hospitalised in a vascular medicine and surgery department, and to evaluate the medication adherence, the knowledge and the importance patients attach to their treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Observational, prospective and a single-centre study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The study was conducted in a French tertiary hospital centre of around 3000 beds in 9 institutions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Adult polymedicated (ie, minimum of five chronic treatments) patients hospitalised in a vascular medicine and surgery department were included after application of the exclusion criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patient interviews were carried out in the department and were based on three interviewer-administered questionnaires (a global questionnaire, the Belief Medical Questionnaire and the GIRERD questionnaire).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our study showed that patients perceived their treatments as beneficial rather than worrying. A correlation between medication adherence and beliefs was observed. \u2018Non-adherent\u2019patients had a more negative overall view of medication than \u2018adherent\u2019 patients. The level of compliance and knowledge of our patients was low. Only 11% of the patients were \u2018good adherent\u2019, 16% of the patients could perfectly name their treatment and 36% knew all the indications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Knowledge of treatment representation and beliefs are central to understanding patient behaviour. Considering patients\u2019 representations will allow the identification of levers, and the development of actions and educational tools adapted to improve their adherence, their knowledge and therefore their drug management.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bmjopen-2023-073250","type":"journal-article","created":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T04:32:52Z","timestamp":1702528372000},"page":"e073250","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Observational and prospective study: evaluation of beliefs and representations of chronic treatments of polymedicated patients hospitalised in a vascular medicine and surgery department"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4993-2484","authenticated-orcid":false,"given":"Dounia","family":"Kotry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justine","family":"Saillard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Bonsergent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christelle","family":"Volteau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Benichou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Prot-Labarthe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8738-4419","authenticated-orcid":false,"given":"Jean-Fran\u00e7ois","family":"Huon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,12,13]]},"reference":[{"key":"2023122506325019000_13.12.e073250.1","unstructured":"Chassang M , Gautier A . Les maladies chroniques [online], . 2019 Available: https:\/\/www.lecese.fr\/sites\/default\/files\/pdf\/Avis\/2019\/2019_14_maladies_chroniques.pdf [Accessed 21 Jan 2022]."},{"key":"2023122506325019000_13.12.e073250.2","unstructured":"WHO . Noncommunicable diseases [online], Available: https:\/\/www.who.int\/fr\/news-room\/fact-sheets\/detail\/noncommunicable-diseases [Accessed 21 Oct 2023]."},{"key":"2023122506325019000_13.12.e073250.3","unstructured":"Brian\u00e7on S , Gu\u00e9rin G , Sandrin-Berthon B . Chronic diseases [online]. 2010."},{"key":"2023122506325019000_13.12.e073250.4","unstructured":"Laroche JP , Guilbert B , Miserey G , et al . Conseil National Professionnel de M\u00e9decine Vasculaire, M\u00e9decine Vasculaire - Etat des lieux [online], . 2015 Available: https:\/\/www.portailvasculaire.fr\/sites\/default\/files\/docs\/livre_blanc_2015.pdf [Accessed 26 Jul 2022]."},{"key":"2023122506325019000_13.12.e073250.5","unstructured":"Mon\u00e9gat M , Sermet C , Perronnin M , et al . La polymedication definitions mesures et enjeux [online], . 2014 Available: https:\/\/www.irdes.fr\/recherche\/questions-d-economie-de-la-sante\/204-la-polymedication-definitions-mesures-et-enjeux.pdf [Accessed 3 Jan 2022]."},{"key":"2023122506325019000_13.12.e073250.6","unstructured":"Le Cossec C . La polym\u00e9dication au regard de diff\u00e9rents indicateurs de sa mesure: impact sur la pr\u00e9valence, les classes th\u00e9rapeutiques concern\u00e9es et les facteurs associ\u00e9s [online], . 2015 Available: https:\/\/www.irdes.fr\/recherche\/rapports\/562-la-polymedication-au-regard-de-differents-indicateurs-de-sa-mesure.pdf [Accessed 3 Jan 2022]."},{"key":"2023122506325019000_13.12.e073250.7","doi-asserted-by":"crossref","unstructured":"Schneider MP , Herzig L , Hugentobler Hampai D , et al . Revue medicale suisse. adh\u00e9sion th\u00e9rapeutique du patient chronique: des concepts \u00e0 la prise en charge ambulatoire [online]. 2013.","DOI":"10.53738\/REVMED.2013.9.386.1032"},{"key":"2023122506325019000_13.12.e073250.8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/JCN.0000000000000249","article-title":"Illness representations, treatment beliefs, medication adherence, and 30-day hospital readmission in adults with chronic heart failure: a prospective Correlational study","volume":"31","author":"Turrise","year":"2016","journal-title":"J Cardiovasc Nurs"},{"key":"2023122506325019000_13.12.e073250.9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/08870449908407311","article-title":"The beliefs about medicines questionnaire: the development and evaluation of a new method for assessing the cognitive representation of medication","volume":"14","author":"Horne","year":"1999","journal-title":"Psychology & Health"},{"key":"2023122506325019000_13.12.e073250.10","unstructured":"Fall E , Gauchet A , Izaute M , et al . Validation of the French version of the beliefs about medicines questionnaire (BMQ) among diabetes and HIV patients [online], . 2014 Available: https:\/\/www.em-consulte.com\/article\/934270\/validation-of-the-french-version-of-the-beliefs-ab [Accessed 3 Jan 2022]."},{"key":"2023122506325019000_13.12.e073250.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(99)00057-4"},{"key":"2023122506325019000_13.12.e073250.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmr.2010.11.003"},{"key":"2023122506325019000_13.12.e073250.13","unstructured":"Girerd X , Hanon O , Anagnostopoulos K , et al . Assessment of antihypertensive compliance using a self-administered questionnaire: development and use in a hypertension clinic. Presse Medicale Paris Fr 1983:1044\u20138."},{"key":"2023122506325019000_13.12.e073250.14","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.pneumo.2015.03.005","article-title":"Croyances des patients envers les th\u00e9rapies cibl\u00e9es orales et leur influence sur l'observance dans le cancer broncho-pulmonaire: une \u00e9tude pilote prospective","volume":"72","author":"Torrecillas","year":"2016","journal-title":"Revue de Pneumologie Clinique"},{"key":"2023122506325019000_13.12.e073250.15","first-page":"138","article-title":"Croyances \u00e0 propos des m\u00e9dicaments et observance chez les patients atteints de maladie chronique","volume":"28","author":"D\u00e9at","year":"2017","journal-title":"Exerc Rev Francoph M\u00e9decine G\u00e9n\u00e9rale"},{"key":"2023122506325019000_13.12.e073250.16","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s40801-015-0041-6","article-title":"How drug use by French elderly patients has changed during the last decade","volume":"2","author":"Huon","year":"2015","journal-title":"Drugs Real World Outcomes"},{"key":"2023122506325019000_13.12.e073250.17","unstructured":"Bruyer B . \u00c9valuation des connaissances que les patients ont de leurs traitements et du temps d\u2019\u00e9ducation th\u00e9rapeutique en consultation de m\u00e9decine g\u00e9n\u00e9rale ou en pharmacie. M\u00e9decine Humaine et Pathologie 2020:ffdumas\u201303054136f."},{"key":"2023122506325019000_13.12.e073250.18","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2002.122853"},{"key":"2023122506325019000_13.12.e073250.19","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1093\/ajhp\/61.23.2523","article-title":"Understanding of drug indications by ambulatory care patients","volume":"61","author":"Persell","year":"2004","journal-title":"Am J Health Syst Pharm"},{"key":"2023122506325019000_13.12.e073250.20","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1020"},{"key":"2023122506325019000_13.12.e073250.21","unstructured":"Haidar-Ahmad F . Factors influencing knowledge of chronic treatment: a study of 351 patients in the 14th, 15th and 16th arrondissements of Marseilles. Sciences Du Vivant [q-Bio] 2019."},{"key":"2023122506325019000_13.12.e073250.22","doi-asserted-by":"crossref","first-page":"10101","DOI":"10.1051\/tpe\/2017002","article-title":"\u00c9valuation des repr\u00e9sentations relatives aux m\u00e9dicaments chez les patients atteints de my\u00e9lome multiple. educ th\u00e9rapeutique patient - ther patient educ","volume":"9","author":"Huon","year":"2017","journal-title":"Educ Ther Patient\/Ther Patient Educ"},{"key":"2023122506325019000_13.12.e073250.23","first-page":"113","article-title":"Est-ce que les sujets \u00e2g\u00e9s connaissent leurs traitements","volume":"31","author":"Oudjhani","year":"2012","journal-title":"J Pharm Clin"},{"key":"2023122506325019000_13.12.e073250.24","doi-asserted-by":"publisher","DOI":"10.1891\/rtnp.16.3.179.53008"},{"key":"2023122506325019000_13.12.e073250.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2006.09.013"},{"key":"2023122506325019000_13.12.e073250.26","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2515\/therapie:2003047","article-title":"Evaluation de l'apport d'une consultation de pharmacie sur les connaissances des patients transplant\u00e9s h\u00e9patiques","volume":"58","author":"Monnier","year":"2003","journal-title":"Therapies"},{"key":"2023122506325019000_13.12.e073250.27","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1007\/s11606-021-06648-1","article-title":"An adaptable framework for factors contributing to medication adherence: results from a systematic review of 102 conceptual frameworks","volume":"36","author":"Peh","year":"2021","journal-title":"J GEN INTERN MED"},{"key":"2023122506325019000_13.12.e073250.28","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s00228-014-1761-3","article-title":"Knowledge, attitudes and beliefs of patients and carers regarding medication adherence: a review of qualitative literature","volume":"70","author":"Kelly","year":"2014","journal-title":"Eur J Clin Pharmacol"},{"key":"2023122506325019000_13.12.e073250.29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.pharma.2012.10.001","article-title":"Comment \u00e9valuer l\u2019adh\u00e9sion m\u00e9dicamenteuse? le point sur les m\u00e9thodes","volume":"71","author":"Allenet","year":"2013","journal-title":"Annales Pharmaceutiques Fran\u00e7aises"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-073250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T22:42:29Z","timestamp":1730846549000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-073250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":29,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12,13]]},"published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1136\/bmjopen-2023-073250"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-073250","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]}}}