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These adverse perinatal outcomes can have both short-term and long-term consequences on maternal mental health. Even though there are few empirical studies on the effect of perinatal loss on maternal mental illness, comprehensive information on the impact of adverse perinatal outcomes in resource-limited settings is scarce. Therefore, we aim to systematically review and synthesise evidence on the effect of adverse perinatal outcomes on maternal mental health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>\n                      The primary outcome of our review will be postpartum maternal mental illness (anxiety, depression, post-traumatic stress disorder and postpartum psychosis) following adverse perinatal outcomes. All peer-reviewed primary studies published in English will be retrieved from databases: PubMed, MEDLINE, CINAHL Ultimate (EBSCO), PsycINFO, Embase, Scopus and Global Health through the three main searching terms\u2014adverse perinatal outcomes, maternal mental illness and settings, with a variant of subject headings and keywords. We will follow the Joanna Briggs Institute critical appraisal checklist to assess the quality of the studies we are including. The review findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 statement. Estimate-based meta-analysis will be performed. We will assess heterogeneity between studies using the I\n                      <jats:sup>2<\/jats:sup>\n                      statistics and publication bias will be checked using funnel plots and Egger\u2019s test. A subgroup analysis will be conducted to explore potential sources of heterogeneity (if available). Finally, the certainty of the evidence will be evaluated using the Grading of Recommendations, Assessment, Development and Evaluation approach.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Since this systematic review does not involve human participants, ethical approval is not required. The review will be submitted for publication in a peer-reviewed journal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42023405980.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-074447","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T02:07:44Z","timestamp":1702606064000},"page":"e074447","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of adverse perinatal outcomes on postpartum maternal mental health in low-income and middle-income countries: a protocol for systematic review"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6312-0267","authenticated-orcid":false,"given":"Samrawit Mihret","family":"Fetene","sequence":"first","affiliation":[{"name":"Department of Health Systems and Policy, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7076-6146","authenticated-orcid":false,"given":"Tsegaye Gebremedhin","family":"Haile","sequence":"additional","affiliation":[{"name":"Department of Health Systems and Policy, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abel","family":"Dadi","sequence":"additional","affiliation":[{"name":"Menzies School of Health Research, Charles Darwin University, Casuarina, Northern Territory, Australia"},{"name":"Addis Continental Institute of Public Health, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,12,14]]},"reference":[{"key":"2025121514594209000_13.12.e074447.1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-053881","article-title":"Predictors of adverse perinatal outcome among women who gave birth at medical center of Southwest Ethiopia: a retrospective cohort study","volume":"12","author":"Jaleta","year":"2022","journal-title":"BMJ Open"},{"key":"2025121514594209000_13.12.e074447.2","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2022.101506","article-title":"Estimating baseline rates of adverse perinatal and neonatal outcomes using a facility-based surveillance approach: A prospective observational study from the WHO global vaccine safety multi-country collaboration on safety in pregnancy","volume":"50","author":"Sharan","year":"2022","journal-title":"EClinicalMedicine"},{"key":"2025121514594209000_13.12.e074447.3","unstructured":"World Health Organization . 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