{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T21:07:53Z","timestamp":1765832873445,"version":"3.48.0"},"reference-count":31,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"unspecified","delay-in-days":27,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007582","name":"Alberta Health Services","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/100007582","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["427774"],"award-info":[{"award-number":["427774"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,5,3]]},"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Hypoxaemic respiratory failure (HRF) affects nearly 15% of critically ill adults admitted to an intensive care unit (ICU). An evidence-based, stakeholder-informed multidisciplinary care pathway (\n                      <jats:italic>Venting Wisely<\/jats:italic>\n                      ) was created to standardise the diagnosis and management of patients with HRF and acute respiratory distress syndrome. Successful adherence to the pathway requires a coordinated team-based approach by the clinician team. The overall aim of this study is to describe the acceptability of the\n                      <jats:italic>Venting Wisely<\/jats:italic>\n                      pathway among critical care clinicians. Specifically, this will allow us to (1) better understand the user\u2019s experience with the intervention and (2) determine if the intervention was delivered as intended.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>\n                      This qualitative study will conduct focus groups with nurse practitioners, physicians, registered nurses and registered respiratory therapists from 17 Alberta ICUs. We will use template analysis to describe the acceptability of a multicomponent care pathway according to seven constructs of acceptability: (1) affective attitude;,(2) burden, (3) ethicality, (4) intervention coherence, (5) opportunity costs, (6) perceived effectiveness and (7) self-efficacy. This study will contribute to a better understanding of the acceptability of the\n                      <jats:italic>Venting Wisely<\/jats:italic>\n                      pathway. Identification of areas of poor acceptability will be used to refine the pathway and implementation strategies as ways to improve adherence to the pathway and promote its sustainability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study was approved by the University of Calgary Conjoint Health Research Ethics Board. The results will be submitted for publication in a peer-reviewed journal and presented at a scientific conference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      ClinicalTrials.gov\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04744298\">NCT04744298<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-075086","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T23:05:28Z","timestamp":1716937528000},"page":"e075086","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Acceptability of the Venting Wisely pathway for use in critically ill adults with hypoxaemic respiratory failure and acute respiratory distress syndrome (ARDS): a qualitative study protocol"],"prefix":"10.1136","volume":"14","clinical-trial-number":[{"clinical-trial-number":"nct04744298","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04744298","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04744298","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04070053","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0300-4122","authenticated-orcid":false,"given":"Karla D","family":"Krewulak","sequence":"first","affiliation":[{"name":"Critical Care Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwen","family":"Knight","sequence":"additional","affiliation":[{"name":"Critical Care Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Irwin","sequence":"additional","affiliation":[{"name":"Critical Care Strategic Clinical Network, Alberta Health Services, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanna","family":"Morrissey","sequence":"additional","affiliation":[{"name":"Critical Care Strategic Clinical Network, Alberta Health Services, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry Thomas","family":"Stelfox","sequence":"additional","affiliation":[{"name":"University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean M","family":"Bagshaw","sequence":"additional","affiliation":[{"name":"University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny","family":"Zuege","sequence":"additional","affiliation":[{"name":"Critical Care Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Roze des Ordons","sequence":"additional","affiliation":[{"name":"Critical Care and Palliative Care, University of Calgary, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7299-6594","authenticated-orcid":false,"given":"Kirsten","family":"Fiest","sequence":"additional","affiliation":[{"name":"Critical Care Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1113-0287","authenticated-orcid":false,"given":"Ken Kuljit Singh","family":"Parhar","sequence":"additional","affiliation":[{"name":"Critical Care Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"2025121513034929000_14.5.e075086.1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0291"},{"key":"2025121513034929000_14.5.e075086.2","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201812-910OC"},{"key":"2025121513034929000_14.5.e075086.3","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.3.7509706"},{"key":"2025121513034929000_14.5.e075086.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050333"},{"key":"2025121513034929000_14.5.e075086.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011802"},{"key":"2025121513034929000_14.5.e075086.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022450"},{"key":"2025121513034929000_14.5.e075086.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.3.345"},{"key":"2025121513034929000_14.5.e075086.8","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.6.9808136"},{"key":"2025121513034929000_14.5.e075086.9","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1602"},{"key":"2025121513034929000_14.5.e075086.10","doi-asserted-by":"publisher","DOI":"10.1513\/annalsats.201512-841oc"},{"key":"2025121513034929000_14.5.e075086.11","doi-asserted-by":"crossref","first-page":"S271","DOI":"10.1513\/AnnalsATS.201704-337OT","article-title":"Low tidal volume versus non-volume-limited strategies for patients with acute respiratory distress syndrome","volume":"14","author":"Walkey","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"2025121513034929000_14.5.e075086.12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005043421801"},{"key":"2025121513034929000_14.5.e075086.13","article-title":"Lung protective ventilation strategy for the acute respiratory distress syndrome","volume":"2013","author":"Petrucci","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"2025121513034929000_14.5.e075086.14","doi-asserted-by":"crossref","DOI":"10.1186\/cc12557","article-title":"Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials","volume":"17","author":"Alhazzani","year":"2013","journal-title":"Crit Care"},{"key":"2025121513034929000_14.5.e075086.15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1214103"},{"key":"2025121513034929000_14.5.e075086.16","unstructured":"Kohn LT , Corrigan J , Donaldson MS . To Err Is Human: Building a Safer Health System. Washington: National Academy Press, 2000."},{"key":"2025121513034929000_14.5.e075086.17","article-title":"Development and content validation of a multidisciplinary standardized management pathway for hypoxemic respiratory failure and acute respiratory distress syndrome","volume":"3","author":"Parhar","year":"2021","journal-title":"Crit Care Explor"},{"key":"2025121513034929000_14.5.e075086.18","doi-asserted-by":"crossref","DOI":"10.1186\/s12913-017-2031-8","article-title":"Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework","volume":"17","author":"Sekhon","year":"2017","journal-title":"BMC Health Serv Res"},{"key":"2025121513034929000_14.5.e075086.19","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-010-0319-7"},{"key":"2025121513034929000_14.5.e075086.20","unstructured":"Parhar K . Identification and treatment of hypoxemic respiratory failure and ARDS with protection,paralysis, and proning pathway Clinicaltrials.Gov Identifier: NCT047442982023. n.d. Available: https:\/\/ClinicalTrials.gov\/show\/NCT04744298"},{"key":"2025121513034929000_14.5.e075086.21","first-page":"207","article-title":"Protocol and statistical analysis plan for the identification and treatment of hypoxemic respiratory failure and acute respiratory distress syndrome with protection, paralysis, and proning: a Type-1 hybrid stepped-wedge cluster randomised effectiveness-implementation study","volume":"25","author":"Parhar","year":"2023","journal-title":"Crit Care Resusc"},{"key":"2025121513034929000_14.5.e075086.22","doi-asserted-by":"crossref","DOI":"10.1136\/bmjoq-2023-002461","article-title":"Designing a behaviour change wheel guided implementation strategy for a hypoxaemic respiratory failure and ARDS care pathway that targets barriers","volume":"12","author":"Parhar","year":"2023","journal-title":"BMJ Open Qual"},{"key":"2025121513034929000_14.5.e075086.23","unstructured":"Parhar KKS . Treatment of Hypoxemic respiratory failure and ARDS with protection, paralysis, and Proning (Therappp) pathway (pilot) Clinicaltrials.Gov Identifier: NCT040700532019. 2023. Available: https:\/\/ClinicalTrials.gov\/show\/NCT04070053 [Accessed 28 Jun 2023]."},{"key":"2025121513034929000_14.5.e075086.24","doi-asserted-by":"crossref","unstructured":"Booth A , Hannes K , Harden A , et al . COREQ (Consolidated criteria for reporting qualitative studies). guidelines for reporting health research: a user\u2019s manual. 2014.214\u201326. doi:10.1002\/9781118715598","DOI":"10.1002\/9781118715598.ch21"},{"key":"2025121513034929000_14.5.e075086.25","doi-asserted-by":"crossref","unstructured":"Krewulak K , Knight G , Irwin A , et al . Acceptability of the venting wisely pathway for use in critically ill adults with hypoxemic respiratory failure and acute respiratory distress syndrome (ARDS): a qualitative study protocol. medRxiv [Preprint] 2023. doi:10.1101\/2023.04.21.23288685","DOI":"10.1101\/2023.04.21.23288685"},{"key":"2025121513034929000_14.5.e075086.26","doi-asserted-by":"crossref","unstructured":"King N . Doing template analysis. In: Symon G Cassell C , eds. Qualitative Organizational Research: Core Methods and Current Challenges. London: SAGE, 2012: 426\u201350.","DOI":"10.4135\/9781526435620.n24"},{"key":"2025121513034929000_14.5.e075086.27","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1080\/14780887.2014.955224","article-title":"The utility of template analysis in qualitative psychology research","volume":"12","author":"Brooks","year":"2015","journal-title":"Qual Res Psychol"},{"key":"2025121513034929000_14.5.e075086.28","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"2025121513034929000_14.5.e075086.29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140141","article-title":"Stakeholder engagement to identify priorities for improving the quality and value of critical care","volume":"10","author":"Stelfox","year":"2015","journal-title":"PLoS One"},{"key":"2025121513034929000_14.5.e075086.30","doi-asserted-by":"crossref","first-page":"e347","DOI":"10.1097\/CCM.0000000000002093","article-title":"Healthcare provider perceptions of causes and consequences of ICU capacity strain in a large publicly funded integrated health region: a qualitative study","volume":"45","author":"Bagshaw","year":"2017","journal-title":"Crit Care Med"},{"key":"2025121513034929000_14.5.e075086.31","doi-asserted-by":"crossref","DOI":"10.1186\/s13012-016-0399-1","article-title":"Integrated knowledge translation (IKT) in health care: a Scoping review","volume":"11","author":"Gagliardi","year":"2016","journal-title":"Implement Sci"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-075086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T21:03:59Z","timestamp":1765832639000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-075086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":31,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5,28]]},"published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1136\/bmjopen-2023-075086"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-075086","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2024,5]]}}}