{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T09:28:48Z","timestamp":1765704528103,"version":"3.46.0"},"reference-count":32,"publisher":"BMJ","issue":"9","license":[{"start":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T00:00:00Z","timestamp":1694908800000},"content-version":"unspecified","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260964"],"award-info":[{"award-number":["82260964"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the \u201cLiang Fanrong Expert Workstation\u201d of Yunnan Province-Yunnan Provincial Science and Technology Plan Project","award":["202305AF150072"],"award-info":[{"award-number":["202305AF150072"]}]},{"name":"the Youth Special of Yunnan Province Ten-thousand Plan","award":["YNWR-QNBJ-2019-257"],"award-info":[{"award-number":["YNWR-QNBJ-2019-257"]}]},{"name":"the \u201cLiu Zili Famous Doctor\u201d special talent program of the Yunnan Provincial Xing Dian Talent Support Program","award":["(Yunnan Party Talent Office [2022] No. 8)"],"award-info":[{"award-number":["(Yunnan Party Talent Office [2022] No. 8)"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,9,5]]},"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Migraine is a widespread neurological disorder characterised by recurrent moderate-to-severe headaches. These headaches can seriously affect patients\u2019 daily life and work, especially during acute attacks when patients often need immediate pain relief. This study aims to assess the immediate analgesic effect of acupuncture for 10\u2009min during acute migraine attacks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>The study will randomly divide 80 participants into either the acupuncture group or the sham acupuncture group with an allocation ratio of 1:1. Each group will receive 10\u2009min of treatment, and the post-treatment evaluation will be performed after 0, 0\u20132, 4, 6, 8 and 10\u2009min of acupuncture. The primary outcome is the pain Visual Analogue Scale (VAS) score assessed before and after treatment at 10\u2009min. Additionally, secondary outcomes include the pain VAS score assessed at 0\u20132, 4, 6 and 8\u2009min, blinding assessment and treatment effectiveness expectations scale. Data will be collected at baseline time and the end of treatment (after 10\u2009min). Adverse events during each treatment period will be collected and recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethics approval was obtained from the Ethics Committee of the Second Affiliated Hospital of Yunnan University of Chinese Medicine (2022\u2013008). All participants will provide written informed consent before randomisation. The results of this study will be published in a peer-reviewed journal and presented at conferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>Chinese Clinical Trial Registration Center (ChiCTR2200066976).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-075715","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T23:12:12Z","timestamp":1695078732000},"page":"e075715","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Immediate analgesic effect of acupuncture intervention within 10 min during acute migraine attacks: protocol of a randomised controlled 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