{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T03:41:03Z","timestamp":1772682063159,"version":"3.50.1"},"reference-count":29,"publisher":"BMJ","issue":"11","license":[{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"unspecified","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Capital\u2019s Funds for Health Improvement and Research","award":["No. 2022-1-4031"],"award-info":[{"award-number":["No. 2022-1-4031"]}]},{"name":"National High Level Hospital Clinical Research Funding of Fuwai Hospital, Chinese Academy of Medical Sciences","award":["2022-GSP-GG-28"],"award-info":[{"award-number":["2022-GSP-GG-28"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,11,5]]},"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The implementation of a heart team still faces many challenges which may be facilitated with advanced communication technology. There is a knowledge gap to support the use of an electronic real-time heart team decision-making approach based on communication technology in the real clinical practice and evaluate its safety and feasibility in patients with complex coronary artery disease (CAD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>The EHEART (Electronic HEArt team with Real-Time decision-making) trial is a prospective, multicentre, two-arm, randomised controlled trial that will randomise 490 patients with complex CAD to either an electronic real-time heart team group or conventional heart team group. For patients allocated to the real-time electronic group, heart team meetings will be initiated during the coronary angiography and guided by a supporting system based on communication technology to help with information synchronisation, real-time communication between specialists, meeting process recording and assistance and joint decision-making with patients\u2019 families. The primary and safety endpoint is a composite of all-cause death, myocardial infarction, stroke, revascularisation or re-angina hospital admission at 1\u2009year. The primary secondary outcome is the time interval from the coronary angiography to the final treatment, which is the major indicator of feasibility. We will also compare the practical feasibility from the specialist\u2019s and patient\u2019s perspectives (for example, specialist\u2019s workload and patient\u2019s decision results) between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study was approved by the Institutional Review Board (IRB) of Fuwai Hospital (no. 2022-1749). Informed consent will be obtained from all participants. The results of this trial will be disseminated through manuscript publication and national\/international conferences, and reported in the trial registry entry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      ClinicalTrials.gov Registry (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"NCT05514210\">NCT05514210<\/jats:ext-link>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-076864","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T12:43:21Z","timestamp":1700570601000},"page":"e076864","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Safety and feasibility of a real-time electronic heart team decision-making approach in patients with complex coronary artery disease: a protocol for a randomised controlled trial (EHEART trial)"],"prefix":"10.1136","volume":"13","clinical-trial-number":[{"clinical-trial-number":"nct05514210","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Xiaoting","family":"Su","sequence":"first","affiliation":[{"name":"National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9465-1060","authenticated-orcid":false,"given":"Hanping","family":"Ma","sequence":"additional","affiliation":[{"name":"National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shen","family":"Lin","sequence":"additional","affiliation":[{"name":"National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"},{"name":"Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8372-6338","authenticated-orcid":false,"given":"Kefei","family":"Dou","sequence":"additional","affiliation":[{"name":"National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"},{"name":"Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9162-6492","authenticated-orcid":false,"given":"Zhe","family":"Zheng","sequence":"additional","affiliation":[{"name":"National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"},{"name":"Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China"},{"name":"National Health Commission Key Laboratory of Cardiovascular Regenerative Medicine, Fuwai Central-China Hospital, Central-China Branch of National Center for Cardiovascular Diseases, Zhengzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,11,21]]},"reference":[{"key":"2025121513545969000_13.11.e076864.1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.014738","article-title":"Multidisciplinary heart team approach for complex coronary artery disease: single center clinical presentation","volume":"9","author":"Young","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2025121513545969000_13.11.e076864.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.01.006"},{"key":"2025121513545969000_13.11.e076864.3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ahj.2019.07.004","article-title":"Ad hoc percutaneous coronary intervention in patients with stable coronary artery disease: a report from the national cardiovascular data Registry Cathpci Registry","volume":"216","author":"Faridi","year":"2019","journal-title":"Am Heart J"},{"key":"2025121513545969000_13.11.e076864.4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1509"},{"key":"2025121513545969000_13.11.e076864.5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.887539"},{"key":"2025121513545969000_13.11.e076864.6","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011279","article-title":"Long-term outcomes following heart team revascularization recommendations in complex coronary artery disease","volume":"8","author":"Patterson","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"2025121513545969000_13.11.e076864.7","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht059"},{"key":"2025121513545969000_13.11.e076864.8","first-page":"815","article-title":"Heart teams: a new paradigm in health care","volume":"34","author":"Mesana","year":"2018","journal-title":"Can J Cardiol"},{"key":"2025121513545969000_13.11.e076864.9","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy394"},{"key":"2025121513545969000_13.11.e076864.10","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jacc.2021.09.005","article-title":"ACC\/AHA\/SCAI guideline for coronary artery Revascularization: executive summary: a report of the American college of cardiology\/American heart Association joint committee on clinical practice guidelines","volume":"79","author":"Lawton","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2025121513545969000_13.11.e076864.11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113241","article-title":"Use of a heart team in decision-making for patients with complex coronary disease at hospitals in Michigan prior to guideline endorsement","volume":"9","author":"Bruckel","year":"2014","journal-title":"PLoS One"},{"key":"2025121513545969000_13.11.e076864.12","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s11748-019-01108-4","article-title":"Enhanced outcomes for coronary artery disease obtained by a multidisciplinary heart team approach","volume":"67","author":"Yamasaki","year":"2019","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"2025121513545969000_13.11.e076864.13","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1111\/jocs.14892","article-title":"The impact of heart team discussion on decision making for coronary revascularization in patients with complex coronary artery disease","volume":"35","author":"Kezerle","year":"2020","journal-title":"J Card Surg"},{"key":"2025121513545969000_13.11.e076864.14","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.20800"},{"key":"2025121513545969000_13.11.e076864.15","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jcmg.2021.08.017","article-title":"Virtual and augmented reality in cardiovascular care: state-of-the-art and future perspectives","volume":"15","author":"Jung","year":"2022","journal-title":"JACC Cardiovasc Imaging"},{"key":"2025121513545969000_13.11.e076864.16","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.e7586","article-title":"SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials","volume":"346","author":"Chan","year":"2013","journal-title":"BMJ"},{"key":"2025121513545969000_13.11.e076864.17","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.c869","article-title":"CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials","volume":"340","author":"Moher","year":"2010","journal-title":"BMJ"},{"key":"2025121513545969000_13.11.e076864.18","doi-asserted-by":"crossref","unstructured":"Hoffmann TC , Glasziou PP , Boutron I , et al . Better reporting of interventions: template for intervention description and replication (Tidier) checklist and guide. BMJ 2014;348. doi:10.1136\/bmj.g1687","DOI":"10.1136\/bmj.g1687"},{"key":"2025121513545969000_13.11.e076864.19","doi-asserted-by":"crossref","DOI":"10.1136\/heartjnl-2021-320510","article-title":"Getting the best from the heart team: guidance for cardiac Multidisciplinary meetings","volume":"108","author":"Archbold","year":"2022","journal-title":"Heart"},{"key":"2025121513545969000_13.11.e076864.20","doi-asserted-by":"crossref","unstructured":"Hart SG , Staveland LE , Hancock PA , et al . Development of NASATLX (Task Load Index): results of empirical and theoretical research. Human mental workload. North-Holland: Oxford, 1988: 139e83.","DOI":"10.1016\/S0166-4115(08)62386-9"},{"key":"2025121513545969000_13.11.e076864.21","doi-asserted-by":"publisher","DOI":"10.1136\/bmjqs-2011-000188"},{"key":"2025121513545969000_13.11.e076864.22","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq240"},{"key":"2025121513545969000_13.11.e076864.23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/CM9.0000000000000592","article-title":"Assessing the Association of appropriateness of coronary Revascularization and 1-year clinical outcomes for patients with stable coronary artery disease in China","volume":"133","author":"Lin","year":"2020","journal-title":"Chin Med J (Engl)"},{"key":"2025121513545969000_13.11.e076864.24","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1001\/jamasurg.2014.2059","article-title":"Safety and efficacy of implementing a multidisciplinary heart team approach for revascularization in patients with complex coronary artery disease: an observational cohort pilot study","volume":"149","author":"Chu","year":"2014","journal-title":"JAMA Surg"},{"key":"2025121513545969000_13.11.e076864.25","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.amjcard.2017.07.021","article-title":"Reconsidering the gatekeeper paradigm for percutaneous coronary intervention in stable coronary disease management","volume":"120","author":"Schulman-Marcus","year":"2017","journal-title":"Am J Cardiol"},{"key":"2025121513545969000_13.11.e076864.26","doi-asserted-by":"publisher","DOI":"10.1136\/bmjinnov-2021-000662"},{"key":"2025121513545969000_13.11.e076864.27","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1093\/eurheartj\/ehac231","article-title":"The promise of the metaverse in cardiovascular health","volume":"43","author":"Mesko","year":"2022","journal-title":"Eur Heart J"},{"key":"2025121513545969000_13.11.e076864.28","doi-asserted-by":"crossref","unstructured":"Patel MR , Calhoon JH , Dehmer GJ , et al . ACC\/AATS\/AHA\/ASE\/ASNC\/SCAI\/SCCT\/STS 2017 appropriate use criteria for coronary revascularization in patients with stable ischemic heart disease: a report of the American college of cardiology appropriate use criteria task force, American association for thoracic surgery. J Am Coll Cardiol 2017. doi:10.1016\/j.jacc.2017.02.001","DOI":"10.1016\/j.jacc.2017.02.001"},{"key":"2025121513545969000_13.11.e076864.29","first-page":"313","article-title":"National center of cardiovascular diseases. Chinese appropriate use criteria for coronary revascularization (in Chinese)","volume":"31","year":"2016","journal-title":"Chin Circ J"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-076864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T21:55:11Z","timestamp":1765835711000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-076864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":29,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,11,21]]},"published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1136\/bmjopen-2023-076864"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-076864","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]}}}