{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:00:07Z","timestamp":1777417207770,"version":"3.51.4"},"reference-count":26,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T00:00:00Z","timestamp":1703721600000},"content-version":"unspecified","delay-in-days":27,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,11,16]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the experiences of patients who have postacute sequelae SARS-CoV-2 infection with internal vibrations and tremors as a prominent component, we leveraged the efforts by Survivor Corps, a grassroots COVID-19 patient advocacy group, to gather information from individuals belonging to its Facebook group with a history of COVID-19 suffering from vibrations and tremors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting and design<\/jats:title>\n                    <jats:p>\n                      A narrative analysis was performed on 140 emails and 450 social media comments from 140 individuals collected as a response to a call to &gt;180 000 individuals participating in Survivor Corps between 15 July and 27 July 2021. We used common coding techniques and the constant comparative method for qualitative data synthesis and categorising emails. Coded data were entered into NVivo V.12 to identify recurrent themes, theme connections and supporting quotations. Comments were analysed using Word Clouds, generated with R V.4.0.3 using\n                      <jats:italic>quanteda<\/jats:italic>\n                      ,\n                      <jats:italic>wordcloud<\/jats:italic>\n                      and\n                      <jats:italic>tm<\/jats:italic>\n                      packages.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Patient-reported long COVID symptom themes and domains related to internal tremors and vibration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The respondents\u2019 emails represented 22 themes and 7 domains pertaining to their experience with internal tremor and vibrations. These domains were as follows: (1) symptom experience, description and anatomic location; (2) initial symptom onset; (3) symptom timing; (4) symptom triggers or alleviators; (5) change from baseline health status; (6) experience with medical establishment and (7) impact on individuals\u2019 lives and livelihood. There were 22 themes in total, each corresponding to one of the broader domains. Among the responses, many described symptoms that varied in location, timing and triggers, occurred soon after their COVID-19 infection, and were markedly debilitating. There were often frustrating experiences with the healthcare system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study describes key themes and experiences among a group of people reporting long COVID and having a prolonged and debilitating symptom complex that prominently features internal tremors and vibrations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-077389","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T12:15:39Z","timestamp":1703765739000},"page":"e077389","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Characterisation of internal tremors and vibration symptoms"],"prefix":"10.1136","volume":"13","author":[{"given":"Dorothy","family":"Massey","sequence":"first","affiliation":[{"name":"Center for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA"},{"name":"Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2789-1758","authenticated-orcid":false,"given":"Mitsuaki","family":"Sawano","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA"},{"name":"Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna D","family":"Baker","sequence":"additional","affiliation":[{"name":"Section of Stroke and Vascular Neurology, Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Berrent","family":"G\u00fcthe","sequence":"additional","affiliation":[{"name":"Survivor Corps, Washington, DC, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"G\u00fcthe","sequence":"additional","affiliation":[{"name":"Survivor Corps, Washington, DC, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne Pincus","family":"Shidlovsky","sequence":"additional","affiliation":[{"name":"Survivor Corps, Washington, DC, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liza","family":"Fisher","sequence":"additional","affiliation":[{"name":"Survivor Corps, Washington, DC, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connor B","family":"Grady","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-9437","authenticated-orcid":false,"given":"Cesar","family":"Caraballo","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA"},{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianna","family":"Zhou","sequence":"additional","affiliation":[{"name":"Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richa","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2046-127X","authenticated-orcid":false,"given":"Harlan M","family":"Krumholz","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research and Evaluation, Yale University, New Haven, Connecticut, USA"},{"name":"Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA"},{"name":"Center for Infection and Immunity, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2023,12,28]]},"reference":[{"key":"2025120521151173000_13.12.e077389.1","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.28568","article-title":"Short-term and long-term rates of Postacute sequelae of SARS-Cov-2 infection: a systematic review","volume":"4","author":"Groff","year":"2021","journal-title":"JAMA Netw Open"},{"key":"2025120521151173000_13.12.e077389.2","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2021.101019","article-title":"Characterizing long COVID in an 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