{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T09:55:06Z","timestamp":1782554106836,"version":"3.54.5"},"reference-count":21,"publisher":"BMJ","issue":"6","license":[{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"unspecified","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2023,12,11]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>This planned scoping review aims to provide insight into current literature regarding perceived quality of life (QoL), functioning and participation of patients with upper limb amputations (ULA) because of therapy-resistant debilitating complex regional pain syndrome type I (CRPS-I) or brachial plexus injury (BPI). It is important to gain insight into these outcomes, so we can properly inform and select patients eligible for amputation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and analysis<\/jats:title>\n                  <jats:p>Joanna Briggs Institute methodology for scoping reviews, Systematic Reviews and Meta-Analyses Scoping Reviews guidelines and Arksey and O\u2019Malley\u2019s framework will be used. Studies regarding adult patients with either BPI or CRPS-I who underwent ULA will be considered for inclusion. Studies should include one or more of the following topics: QoL, functioning or participation and should be written in English, German or Dutch. Searches will be conducted in the Cochrane database, PubMed, EMBASE and Google Scholar. Search strings will be provided by a licenced librarian. All relevant literatures will be considered for inclusion, regardless of published date, in order to give a full scope of available literature. Studies will be selected first by title, then abstract and finally by full article by two reviewers who will discuss after every round. A third reviewer will make final decisions to reach consensus if needed. Data will be presented as brief summaries and in tables using a modified data extraction table.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Ethics and dissemination<\/jats:title>\n                  <jats:p>No ethical approval is required since no original data will be collected. Results will be disseminated through publication in a peer-reviewed journal and presentations at (inter)national conferences.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-079393","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T21:41:14Z","timestamp":1717623674000},"page":"e079393","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Quality of life, functioning and participation of adult patients with an amputation following complex regional pain syndrome I or brachial plexus injury: a scoping review protocol"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0126-9151","authenticated-orcid":false,"given":"Patrick","family":"Domerchie","sequence":"first","affiliation":[{"name":"Rehabilitation, University Medical Centre Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaske","family":"van Kammen","sequence":"additional","affiliation":[{"name":"Rehabilitation, University Medical Centre Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"van Wijk","sequence":"additional","affiliation":[{"name":"Rehabilitation, Revalidation Centre De Hoogstraat, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maaike","family":"Lange","sequence":"additional","affiliation":[{"name":"Rehabilitation, Revalidation Centre De Hoogstraat, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corry K","family":"Van der Sluis","sequence":"additional","affiliation":[{"name":"Rehabilitation, University Medical Centre Groningen, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,6,5]]},"reference":[{"key":"2025101811203598000_14.6.e079393.1","doi-asserted-by":"crossref","DOI":"10.1007\/s11916-018-0667-7","article-title":"Complex regional pain syndrome, current concepts and treatment options","volume":"22","author":"Urits","year":"2018","journal-title":"Curr Pain Headache Rep"},{"key":"2025101811203598000_14.6.e079393.2","unstructured":"NVA\/VRA . Richtlijn complex Regionaal Pijn Syndroom type 1. 2021. Available: https:\/\/richtlijnendatabase.nl\/richtlijn\/complex_regionaal_pijn_syndroom_type_1\/startpagina_-_complex_regionaal_pijnsyndroom.html"},{"key":"2025101811203598000_14.6.e079393.3","unstructured":"Royal College of Physicians . Complex regional pain syndrome in adults. 2018. Available: https:\/\/www.rcplondon.ac.uk\/guidelines-policy\/complex-regional-pain-syndrome-adults"},{"key":"2025101811203598000_14.6.e079393.4","first-page":"S126","article-title":"The therapeutic approach to complex regional pain syndrome: light and shade","volume":"33","author":"Casale","year":"2015","journal-title":"Clin Exp Rheumatol"},{"key":"2025101811203598000_14.6.e079393.5","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.L.00532"},{"key":"2025101811203598000_14.6.e079393.6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.mehy.2018.08.026","article-title":"Decision making process for amputation in case of therapy resistant complex regional pain syndrome type-I in a Dutch specialist centre","volume":"121","author":"Schrier","year":"2018","journal-title":"Med Hypotheses"},{"key":"2025101811203598000_14.6.e079393.7","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.J.01329"},{"key":"2025101811203598000_14.6.e079393.8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0178642","article-title":"Use of the DEKA arm for Amputees with brachial plexus injury: A case series","volume":"12","author":"Resnik","year":"2017","journal-title":"PLoS One"},{"key":"2025101811203598000_14.6.e079393.9","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0020-1383(93)90123-N","article-title":"Brachial plexus injury: when to amputate?","volume":"24","author":"Wilkinson","year":"1993","journal-title":"Injury"},{"key":"2025101811203598000_14.6.e079393.10","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1302\/0301-620X.98B4.36422","article-title":"Amputation in patients with complex regional pain syndrome: a comparative study between amputees and nonamputees with intractable disease","volume":"98-B","author":"Midbari","year":"2016","journal-title":"Bone Joint J"},{"key":"2025101811203598000_14.6.e079393.11","doi-asserted-by":"crossref","first-page":"929","DOI":"10.3346\/jkms.2012.27.8.929","article-title":"Relationship between complex regional pain syndrome and working life: a Korean study","volume":"27","author":"Kang","year":"2012","journal-title":"J Korean Med Sci"},{"key":"2025101811203598000_14.6.e079393.12","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1302\/2058-5241.4.190008","article-title":"Quality of life after amputation in patients with advanced complex regional pain syndrome: a systematic review","volume":"4","author":"Ayyaswamy","year":"2019","journal-title":"EFORT Open Rev"},{"key":"2025101811203598000_14.6.e079393.13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ijotn.2015.11.001","article-title":"Quality of life following traumatic brachial plexus injury: a questionnaire study","volume":"22","author":"Gray","year":"2016","journal-title":"Int J Orthop Trauma Nurs"},{"key":"2025101811203598000_14.6.e079393.14","doi-asserted-by":"crossref","first-page":"838","DOI":"10.3109\/09638288.2013.822023","article-title":"Resilience in patients with amputation because of complex regional pain syndrome type I","volume":"36","author":"Bodde","year":"2014","journal-title":"Disabil Rehabil"},{"key":"2025101811203598000_14.6.e079393.15","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0850"},{"key":"2025101811203598000_14.6.e079393.16","unstructured":"Peters MDJ , Godfrey C , McInerney P , et al . 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