{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:46:13Z","timestamp":1778931973094,"version":"3.51.4"},"reference-count":62,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"unspecified","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,6,2]]},"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study is to determine the pooled prevalence of active trachoma among 1\u20139 years old children in Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A systematic review and meta-analysis were employed in accordance with the Preferred Reporting Items for Systematic Reviews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources<\/jats:title>\n                    <jats:p>Medline\/PubMed, Scopus, Web of Science, African Journal of Online and Google scholar databases were systematically explored to find studies published in English until July 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria<\/jats:title>\n                    <jats:p>The following criteria apply: (1) condition (Co): studies examined the prevalence of trachoma among children (1\u20139) years old; (2) context (Co): studies conducted in Ethiopia; (3) population (Pop): studies that were done among children (1\u20139) years old; (4) study type: observational studies and (5) language: studies published in English.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data extraction and synthesis<\/jats:title>\n                    <jats:p>\n                      The data were extracted using a Microsoft Excel spreadsheet. DerSimonian-Laird random effect model was used to estimate the pooled prevalence of active trachoma among 1\u20139 years old children. Cochrane Q-tests and I\n                      <jats:sup>2<\/jats:sup>\n                      statistics were used across studies to assess heterogeneity. To identify possible publication bias, Egger\u2019s test was performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Primary outcome<\/jats:title>\n                    <jats:p>Prevalence of active trachoma among children aged (1-9 years old)\".<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, a total of 42 articles with 235\u2009005 study participants were included in the final analysis. The estimated pooled prevalence of active trachoma using random effect model was 24% (95% CI 20% to 27%). The subgroup analysis by region revealed that the highest prevalence of trachoma was 36% (95% CI 13% to 58%) in the Tigray region, and publication year revealed the prevalence of trachoma was decreasing from 32% to 19% after 2015.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this review, the pooled prevalence of active trachoma was found to be high in Ethiopia compared with WHO threshold level. This underscores the need for increased focus on high-risk age groups to decrease trachoma and to achieve the elimination of trachoma from the country by 2030.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-079623","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T05:00:47Z","timestamp":1720674047000},"page":"e079623","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Prevalence of active trachoma among 1\u20139 years of age children in Ethiopia: a systematic review and meta-analysis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5226-1200","authenticated-orcid":false,"given":"Yordanos Sisay","family":"Asgedom","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Wolaita Sodo University, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8373-5309","authenticated-orcid":false,"given":"Tsegaye","family":"Melaku","sequence":"additional","affiliation":[{"name":"Institute of Health, Jimma University, Jimma, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0960-3759","authenticated-orcid":false,"given":"Amanuel Yosef","family":"Gebrekidan","sequence":"additional","affiliation":[{"name":"School of Public Health, Wolaita Sodo University, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengistu","family":"Meskele","sequence":"additional","affiliation":[{"name":"School of Public Health, Wolaita Sodo University, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6347-8648","authenticated-orcid":false,"given":"Gedeon","family":"Asnake","sequence":"additional","affiliation":[{"name":"Midwifery, Hawassa University, Hawassa, Southern Nations, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5862-2521","authenticated-orcid":false,"given":"Afework","family":"Alemu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Wolaita Sodo University, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelework Gonfa","family":"Efa","sequence":"additional","affiliation":[{"name":"Department of Medicine, SNNPR, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirubel Eshetu","family":"Haile","sequence":"additional","affiliation":[{"name":"Department of Nursing, Wolaita Sodo University, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gizachew Ambaw","family":"Kassie","sequence":"additional","affiliation":[{"name":"Wolaita Sodo University, Sodo, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"2025121509001411000_14.7.e079623.1","unstructured":"World Health Organization . 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