{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T03:10:09Z","timestamp":1788491409695,"version":"build-2803163510"},"reference-count":23,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"unspecified","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"2022 Huazhong University of Science and Technology Union Shenzhen Hospital Nursing Program","award":["YN2022040"],"award-info":[{"award-number":["YN2022040"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,1,22]]},"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to explore the incidence of, and risk factors for medical adhesive-related skin injury (MARSI) at peripherally inserted central venous catheter (PICC) sites in patients with cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A prospective observational cohort study was conducted at a tertiary hospital in Shenzhen, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>This was a single-centre study conducted in a tertiary hospital in Shenzhen, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 340 patients with cancer and PICC placement from January 2022 to June 2023 were selected using a convenience sampling method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Factors potentially associated with PICC-related MARSI (PICC-MARSI) were recorded, including patient demographics, and catheter placement and maintenance. Patients were divided into MARSI and non-MARSI groups. Univariate analysis was performed to screen for associated variables, and logistic regression analysis was used to identify independent risk factors for PICC-MARSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of all 340 patients enrolled, 33 (9.7%) developed PICC-MARSI, including skin tear (8, 24.2%), tension injury (5, 15.2%), irritant contact dermatitis (10, 30.3%), allergic dermatitis (7, 21.2%) and maceration (3, 9.1%). Multivariable analysis showed that age (OR=1.058, p=0.001, 95% CI 1.023\u20131.094), wet skin (OR=4.873, p=0.003, 95%\u2009CI 1.728\u201313.742), dry skin (OR=6.247, p&lt;0.0001, 95%\u2009CI 2.239\u201317.431), oedema (OR=3.302, p=0.008, 95%\u2009CI 1.365\u20137.985), allergy history (OR=6.044, p=0.001, 95%\u2009CI 2.040\u201317.906), dressing type (OR=3.827, p=0.003, 95%\u2009CI 1.595\u20139.185), body mass index (BMI) &lt;18.5 (OR=4.271, p=0.015, 95%\u2009CI 1.327\u201313.742) and BMI 25\u201330 (OR=2.946, p=0.027, 95%\u2009CI 1.131\u20137.678) were independent risk factors for PICC-MARSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Proper catheter maintenance and appropriate dressing selection are crucial for the prevention of this condition.<\/jats:p>\n                  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