{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:00:04Z","timestamp":1770742804314,"version":"3.49.0"},"reference-count":21,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"unspecified","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the Priority Academic Program Development of Jiangsu Higher Education Institutions","award":["Integration of Chinese and Western Medicine"],"award-info":[{"award-number":["Integration of Chinese and Western Medicine"]}]},{"name":"Research Practice Innovation Program of Jiangsu Province","award":["SJCX23_0891"],"award-info":[{"award-number":["SJCX23_0891"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,7,16]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Two-dimensional shear wave elastography (2D-SWE) is a non-invasive technique for the evaluation of Sj\u00f6gren\u2019s disease (SjD). This study investigated the diagnostic accuracy of 2D-SWE in assessing major salivary gland involvement in SjD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources<\/jats:title>\n                    <jats:p>Data were obtained by searching PubMed, MEDLINE, EMBASE, Scopus, Cochrane library and CNKI from 1999 to 26 September 2022, which includes randomised clinical trial of 2D-SWE for the diagnosis of SjD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria<\/jats:title>\n                    <jats:p>(1) Patients (\u226518 years old) diagnosed with SjD following the international classification in 2002 or 2016 American College of Rheumatology-European League Against Rheumatism classification criteria for SjD; (2) The purpose of this study was to evaluate the diagnostic value of 2D-SWE in SjD; (3) The evaluation parameters for the diagnosis of SjD can be extracted or indirectly obtained in this article, including sensitivity, specificity, true positive, false positive, false negative, true negative, diagnostic point (Young\u2019s modulus) and other data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data extraction and synthesis<\/jats:title>\n                    <jats:p>Four authors independently screened and assessed the literature and extracted the data. RevMan V.5.3 and StataMP V.18 software were used for quality assessment and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 8 studies with a total of 912 cases, including 509 patients with SjD. The high-risk bias in the quality evaluation focused on patient selection and index test. The pooled sensitivity, specificity and summary area under the curve of 2D-SWE were 0.75 (95% CI 0.62 to 0.84), 0.89 (95% CI 0.80 to 0.94) and 0.90 (95% CI 0.87 to 0.92), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>2D-SWE has an acceptable diagnostic accuracy for SjD patients and is an effective tool for auxiliary diagnosis of SjD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42022365766.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-081015","type":"journal-article","created":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T06:10:15Z","timestamp":1723875015000},"page":"e081015","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Accuracy of two-dimensional transverse wave elastography of salivary glands in diagnosis of Sj\u00f6gren\u2019s disease: a systematic review and meta-analysis"],"prefix":"10.1136","volume":"14","author":[{"given":"Jie","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangsha","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoqiu","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruirui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Nanjing General Hospital of Nanjing Military Command, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guquan","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Imaging, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2262-416X","authenticated-orcid":false,"given":"Xiaojin","family":"He","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"2025121401470609000_14.8.e081015.1","article-title":"Tackling heterogeneity in Sj\u00f6gren\u2019s disease","volume":"6","year":"2024","journal-title":"Lancet Rheumatol"},{"key":"2025121401470609000_14.8.e081015.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2017.01.020"},{"key":"2025121401470609000_14.8.e081015.3","doi-asserted-by":"crossref","first-page":"16047","DOI":"10.1038\/nrdp.2016.47","article-title":"Sj\u00f6gren syndrome","volume":"2","author":"Brito-Zer\u00f3n","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"2025121401470609000_14.8.e081015.4","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210448"},{"key":"2025121401470609000_14.8.e081015.5","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2017160116"},{"key":"2025121401470609000_14.8.e081015.6","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.118267","article-title":"Combining surface-enhanced Raman scattering (SERS) of saliva and two-dimensional shear wave elastography (2D-SWE) of the parotid glands in the diagnosis of Sj\u00f6gren\u2019s syndrome","volume":"235","author":"Moisoiu","year":"2020","journal-title":"Spectrochim Acta A Mol Biomol Spectrosc"},{"key":"2025121401470609000_14.8.e081015.7","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s00296-022-05120-5","article-title":"Shear wave elastography as a potential additional diagnostic tool in primary Sj\u00f6gren\u2019s syndrome: an observational study","volume":"42","author":"\u015awiecka","year":"2022","journal-title":"Rheumatol Int"},{"key":"2025121401470609000_14.8.e081015.8","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.6.554"},{"key":"2025121401470609000_14.8.e081015.9","doi-asserted-by":"publisher","DOI":"10.1002\/art.39859"},{"key":"2025121401470609000_14.8.e081015.10","doi-asserted-by":"publisher","DOI":"10.1059\/0003-4819-155-8-201110180-00009"},{"key":"2025121401470609000_14.8.e081015.11","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s00296-020-04548-x","article-title":"Shear wave elastography as a new method to identify parotid lymphoma in primary Sj\u00f6gren Syndrome patients: an observational study","volume":"40","author":"B\u0103d\u0103r\u00eenz\u0103","year":"2020","journal-title":"Rheumatol Int"},{"key":"2025121401470609000_14.8.e081015.12","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1002\/jum.15179","article-title":"Two-dimensional shear wave elastography in the assessment of salivary gland involvement in primary Sj\u00f6gren\u2019s syndrome","volume":"39","author":"Arslan","year":"2020","journal-title":"J Ultrasound Med"},{"key":"2025121401470609000_14.8.e081015.13","first-page":"56","article-title":"Clinical value of 2D-SWE combined with SGUS in evaluating parotid gland lesions of SS","volume":"48","author":"Zhang","year":"2022","journal-title":"J Lanzhou Univ (Med Ed)"},{"key":"2025121401470609000_14.8.e081015.14","first-page":"197","article-title":"Diagnostic value of shear wave elastography combined with MRI in salivary gland lesions of Sj\u00f6gren\u2019s syndrome","volume":"24","author":"Zhao","year":"2022","journal-title":"J Clin Ultrasound Med"},{"key":"2025121401470609000_14.8.e081015.15","first-page":"709","article-title":"Clinical value of shear wave elastography and salivary gland ultrasound scoring in the diagnosis of salivary gland lesions in Sj\u00f6gren\u2019s syndrome","volume":"30","author":"Tang","year":"2021","journal-title":"Chin J Ultrasound Imaging"},{"key":"2025121401470609000_14.8.e081015.16","first-page":"773","article-title":"The value of real-time shear wave elastography combined with ultrasound score in the diagnosis of parotid gland damage in primary Sj\u00f6gren\u2019s syndrome","volume":"30","author":"Wang","year":"2019","journal-title":"Chin J Clin Med Imaging"},{"key":"2025121401470609000_14.8.e081015.17","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jclinepi.2023.07.020","article-title":"The walking man approach to interpreting the receiver operating characteristic curve and area under the receiver operating characteristic curve","volume":"162","author":"Kohn","year":"2023","journal-title":"J Clin Epidemiol"},{"key":"2025121401470609000_14.8.e081015.18","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-316204"},{"key":"2025121401470609000_14.8.e081015.19","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s11547-022-01559-5","article-title":"2D shear wave elastography in evaluation of prognostic factors in breast cancer","volume":"127","author":"Ventura","year":"2022","journal-title":"Radiol Med"},{"key":"2025121401470609000_14.8.e081015.20","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1007\/s00330-014-3320-9","article-title":"Diagnostic performance of shear wave elastography in the identification of malignant thyroid nodules: a meta-analysis","volume":"24","author":"Lin","year":"2014","journal-title":"Eur Radiol"},{"key":"2025121401470609000_14.8.e081015.21","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-021-00605-2"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-081015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T09:47:13Z","timestamp":1765705633000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-081015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":21,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8,17]]},"published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1136\/bmjopen-2023-081015"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-081015","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8]]}}}