{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T21:39:47Z","timestamp":1790458787504,"version":"4.1.0"},"reference-count":43,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"unspecified","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Development Research Institute (IRD) through West African Network of African Center of Excellence on Infectious Diseases","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,12,2]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"\n Objective<\/jats:title>\n This study aimed to assess the prevalence and risk factors for neonatal sepsis among neonates admitted to selected health facilities in the Bamako district and Koulikoro region in Mali.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n This is a prospective cross-sectional study. Data were analyses using bivariate and multivariate logistic regression.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n This facility-based study was conducted in four health facilities consisting of two hospitals and two reference health centres in Mali.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n The study participants comprised 795 randomly selected neonates and their indexed mother.<\/jats:p>\n <\/jats:sec>\n \n Outcome measures<\/jats:title>\n The primary outcome of the study was the prevalence of sepsis in the considered health facilities. The other variables of interest were risk factors for sepsis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The prevalence of neonatal sepsis among the study population was 21.00%. More than 74% of sepsis cases were early onset (<72\u2009hours). Neonatal age <7\u2009days (AOR=2.79, 95%\u2009CI 1.59 to 4.89, p=0.000), low birth weight <2500\u2009g (AOR=2.88, 95%\u2009CI 1.41 to 5.86, p=0.003), Apgar score <7 (AOR=4.03, 95%\u2009CI 3.09 to 5.24, p=0.000), mother with no education (AOR=2.24, 95%\u2009CI 1.15 to 4.33, p=0.02), maternal fever (AOR=2.31, 95%\u2009CI 1.53 to 3.53, p=0.000), prolonged rupture of membranes (AOR=1.87, 95%\u2009CI 1.01 to 3.54, p=0.04) and prolonged labour (AOR=2, 95%\u2009CI 1.03 to 3.88, p=0.04) were significantly associated with neonatal sepsis.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The prevalence of sepsis in Mali is still high. Given the country\u2019s current security context, the findings in this study can support prevention activities, particularly given the limited resources available. It is essential to facilitate antenatal and postnatal visits, to promote in-facility births and rigorous monitoring of neonates at high risk of sepsis. Furthermore, it would be beneficial for future research on neonatal sepsis to include neonates born at home.<\/jats:p>\n <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-082066","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T16:25:19Z","timestamp":1736267119000},"page":"e082066","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence and factors associated with neonatal sepsis in Mali: a cross-sectional study"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2984-9353","authenticated-orcid":false,"given":"Fatoumata Bintou","family":"Traor\u00e9","sequence":"first","affiliation":[{"name":"Gamal Abdel Nasser University of Conakry, Conakry, Guinea"},{"name":"Research, National Institute of Public Health, Bamako, Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bienvenu Salim","family":"Camara","sequence":"additional","affiliation":[{"name":"UGANC, Conakry, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elhadj Marouf","family":"Diallo","sequence":"additional","affiliation":[{"name":"African Centre of Excellence for the Prevention and Control of Communicable Diseases, University of Conakry, Conakry, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7101-5408","authenticated-orcid":false,"given":"Cheick Sidya","family":"Sidib\u00e9","sequence":"additional","affiliation":[{"name":"Vrije Universiteit Amsterdam Athena Instituut, Amsterdam, North Holland, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alhassane","family":"Diallo","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Montpellier 1, Montpellier, Occitanie, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7905-9042","authenticated-orcid":false,"given":"Sidikiba","family":"Sidib\u00e9","sequence":"additional","affiliation":[{"name":"University of Conakry, Department of Public Health, Universite Gamal Abdel Nasser de Conakry, Faculte des Sciences et Techniques de la Sante, Conakry, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birama Apho","family":"LY","sequence":"additional","affiliation":[{"name":"USTTB FMOS, Bamako, Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatimata","family":"Yaro","sequence":"additional","affiliation":[{"name":"National Institute of Public Health, Bamako, Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"Traor\u00e9","sequence":"additional","affiliation":[{"name":"National Institute of Public Health, Bamako, Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoua","family":"Dembel\u00e9","sequence":"additional","affiliation":[{"name":"National Institute of Public Health, Bamako, Mali"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulaye","family":"Tour\u00e9","sequence":"additional","affiliation":[{"name":"Center of Research and Training in Infectious Diseases, Gamal Abdel Nasser University of Conakry, Conakry, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alioune","family":"Camara","sequence":"additional","affiliation":[{"name":"National Malaria Control Programme, Guinea, Conakry, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Delamou","sequence":"additional","affiliation":[{"name":"African Centre of Excellence for the Prevention and Control of Communicable Diseases, University of Conakry, Conakry, 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