{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T20:52:21Z","timestamp":1779396741506,"version":"3.53.1"},"reference-count":32,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T00:00:00Z","timestamp":1724630400000},"content-version":"unspecified","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Scientific and Technological Innovation Project of the General Administration of Sport of China","award":["22KJCX009"],"award-info":[{"award-number":["22KJCX009"]}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2022NSFSC1529"],"award-info":[{"award-number":["2022NSFSC1529"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2024NSFSC0578"],"award-info":[{"award-number":["2024NSFSC0578"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fund of Key Laboratory for Sports Medicine of Sichuan Province & General Administration of Sport","award":["2023-A055"],"award-info":[{"award-number":["2023-A055"]}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"crossref","award":["YJ202346"],"award-info":[{"award-number":["YJ202346"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Innovation Project of Key Laboratory for Sports Medicine of Sichuan Province & General Administration of Sport","award":["SCZJJCC 02"],"award-info":[{"award-number":["SCZJJCC 02"]}]},{"name":"High-level Talents Program of Chengdu Sport University","award":["D400828"],"award-info":[{"award-number":["D400828"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,7,26]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Obesity is a major public health issue in China and around the world. While acupuncture is often used in clinical practice, there is a lack of conclusive evidence for its weight-loss effect. Thus we will conduct a parallel, randomised, sham-controlled trial to evaluate the efficacy and safety of acupuncture for treating obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>\n                      A total of 160 eligible participants with obesity will be randomly assigned to the verum acupuncture group or sham acupuncture group at a ratio of 1:1. All participants will be treated three times a week for a duration of 12 weeks, and followed up for another 16 weeks. The primary outcome is the percentage change in body weight from baseline to Week 12. The secondary outcomes include body mass index (BMI), waist circumference (WC), body fat percentage (BF%), blood pressure, fasting blood glucose, insulin, glycosylated haemoglobin A1c, blood lipids, and physical functioning score on the Short Form 36 Health Survey. Other secondary outcomes including psychological and social functions will also be evaluated using the\n                      <jats:named-content content-type=\"\">body image scale, psychological function scale, and social function scale of the BODY-Q,<\/jats:named-content>\n                      <jats:named-content content-type=\"\">Rosenberg Self-Esteem Scale,<\/jats:named-content>\n                      Patient\n                      <jats:named-content content-type=\"\">Health Questionnaire-9, and Dutch Eating Behaviour Questionnaire<\/jats:named-content>\n                      <jats:named-content content-type=\"\">. BMI, WC, BF% and blood pressure will be evaluated at<\/jats:named-content>\n                      W\n                      <jats:named-content content-type=\"\">eek<\/jats:named-content>\n                      <jats:named-content content-type=\"\">0, 4, 8, 12 and 28. Other secondary outcomes will be measured at<\/jats:named-content>\n                      W\n                      <jats:named-content content-type=\"\">eek<\/jats:named-content>\n                      <jats:named-content content-type=\"\">0, 12 and 28, respectively. Adverse events will be recorded in detail during the trial.<\/jats:named-content>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethical approval of this trial was granted by the Ethics Committee of Chengdu Sport University (2023\u2013102). Written informed consent will be obtained from study participants before enrolment. The findings will be disseminated through peer-reviewed journals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>Chinese Clinical Trial Registry (ChiCTR2200062092).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-083158","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T09:05:15Z","timestamp":1724663115000},"page":"e083158","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Acupuncture for obesity: study protocol for a randomised controlled trial"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7438-1254","authenticated-orcid":false,"given":"Xinyu","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4920-6515","authenticated-orcid":false,"given":"Yang","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan, China"},{"name":"Postdoctoral Workstation, Affiliated Sport Hospital of Chengdu Sport University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Li","sequence":"additional","affiliation":[{"name":"School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nianwei","family":"Wu","sequence":"additional","affiliation":[{"name":"Section of Epidemiology and Population Health & Department of Gynecology and Obstetrics, Ministry of Education Key Laboratory of Birth Defects and Related Diseases of Women and Children & National Medical Products Administration Key Laboratory for Technical Research on Drug Products In Vitro and In Vivo Correlation, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China"},{"name":"West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Section of Epidemiology and Population Health & Department of Gynecology and Obstetrics, Ministry of Education Key Laboratory of Birth Defects and Related Diseases of Women and Children & National Medical Products Administration Key Laboratory for Technical Research on Drug Products In Vitro and In Vivo Correlation, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyi","family":"Wu","sequence":"additional","affiliation":[{"name":"Section of Epidemiology and Population Health & Department of Gynecology and Obstetrics, Ministry of Education Key Laboratory of Birth Defects and Related Diseases of Women and Children & National Medical Products Administration Key Laboratory for Technical Research on Drug Products In Vitro and In Vivo Correlation, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiqun","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximei","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan, 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