{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:22:51Z","timestamp":1784128971964,"version":"3.55.0"},"reference-count":42,"publisher":"BMJ","issue":"6","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"unspecified","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,6,3]]},"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify determinants of puerperal sepsis among postpartum women attending East Shoa Zone public hospitals, Central Ethiopia, 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and setting<\/jats:title>\n                    <jats:p>An institutional-based, unmatched case\u2013control study was conducted from 19 June 2023 to 4 September 2023, in East Shoa Zone public hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>495 postpartum women (100 cases and 395 controls) were selected using systematic sampling techniques. Data were collected through face-to-face interviews and from medical charts using a pretested, structured questionnaire. The AOR with its corresponding 95% CI was used to identify determinant variables. Findings were presented in texts and tables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome measures<\/jats:title>\n                    <jats:p>The medical charts of participants were reviewed to identify those who had developed puerperal sepsis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Anaemia (AOR 6.05; 95%\u2009CI 2.57 to 14.26), undernourishment (AOR 4.43; 95%\u2009CI 1.96 to 10.01), gestational diabetes mellitus (AOR 3.26; 95%\u2009CI 1.22 to 8.74), postpartum haemorrhage (AOR 3.17; 95%\u2009CI 1.28 to 7.87), obstructed labour (AOR 2.76; 95%\u2009CI 1.17 to 6.52), multiparity (AOR 2.54; 95%\u2009CI 1.17 to 5.50), placenta previa (AOR 2.27; 95%\u2009CI 1.11 to 4.67) and vaginal examination \u22655 times (AOR 2.19; 95%\u2009CI 1.05 to 4.54) were the independent determinants of puerperal sepsis in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study found that gestational diabetes mellitus, anaemia, undernourishment, placenta previa, obstructed labour, postpartum haemorrhage and five or more per-vaginal examinations during labour were the determinants of puerperal sepsis. Therefore, it is recommended that obstetric care providers strictly adhere to guidelines on the number of vaginal exams that should be performed throughout labour and that they perform these exams using the appropriate infection-prevention techniques. In addition, they should provide comprehensive health education on nutrition during pregnancy and postnatal periods and the importance of iron supplements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-083230","type":"journal-article","created":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T00:52:18Z","timestamp":1719017538000},"page":"e083230","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Determinants of puerperal sepsis among postpartum women: a case\u2013control study in East Shoa Zone public hospitals, Central Ethiopia"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8909-1209","authenticated-orcid":false,"given":"Befekadu Tesfaye","family":"Oyato","sequence":"first","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tirunesh","family":"Debele","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejene","family":"Edosa","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7684-4339","authenticated-orcid":false,"given":"Husen Zakir","family":"Abasimel","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6923-6650","authenticated-orcid":false,"given":"Mukemil","family":"Awol","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni Tesfaye","family":"Kebede","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andualem","family":"Gezahagn","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adugna Alemu","family":"Desta","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fikadu Tolesa","family":"Alemu","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel Boja","family":"Asfaw","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Salale University, Fitche, Oromia, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"2025121400225998000_14.6.e083230.1","unstructured":"Abebaw N . Assessment of the prevalence and associated factors of Puerparal sepsis among PNC women during post -Partum period at Dessie Referal hospital, Ethiopia. 2018;1\u201339."},{"key":"2025121400225998000_14.6.e083230.2","unstructured":"WHO . Education material for teachers of Midwifery. 2008."},{"key":"2025121400225998000_14.6.e083230.3","unstructured":"WHO . Global report on the Epidimology and burden of sepsis current evidence, identifying gaps and future directions. 2020."},{"key":"2025121400225998000_14.6.e083230.4","doi-asserted-by":"crossref","first-page":"4978","DOI":"10.18203\/2394-6040.ijcmph20205173","article-title":"Puerperal sepsis and maternal outcome in developing countries: an observational study","volume":"7","author":"Kumar","year":"2020","journal-title":"Int J Community Med Public Health"},{"key":"2025121400225998000_14.6.e083230.5","unstructured":"Lopez JP , M\u00fcller EA . Late Purperal sepsis, case report and literature review. Case Reports 2016;17\u201326. Available: https:\/\/api.semanticscholar.org\/CorpusID:79435352"},{"key":"2025121400225998000_14.6.e083230.6","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ijoa.2018.04.010","article-title":"Sepsis in pregnancy and the Puerperium","volume":"36","author":"Burlinson","year":"2018","journal-title":"Int J Obstet Anesth"},{"key":"2025121400225998000_14.6.e083230.7","doi-asserted-by":"crossref","DOI":"10.7189\/jogh.11.04048","article-title":"Causes of maternal mortality in Sub- Saharan Africa: A systematic review of studies published from 2015 to 2020","volume":"11","author":"Musarandega","year":"2021","journal-title":"J Glob Health"},{"key":"2025121400225998000_14.6.e083230.8","doi-asserted-by":"crossref","unstructured":"Ayele H , Baye F , Bishaw G , et al . Predictors ofpost partum sepsis directly related to pnuemonia among post-partum women at finote selam general hospital, west gojjam zone, amhara, ethiopia, 2022. In Review [Preprint] 2023. doi:10.21203\/rs.3.rs-2632719\/v1","DOI":"10.21203\/rs.3.rs-2632719\/v1"},{"key":"2025121400225998000_14.6.e083230.9","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1080\/14767058.2017.1421933","article-title":"A clinical and Microbiological study of Puerperal sepsis in a tertiary care hospital in India","volume":"32","author":"Vanukuru","year":"2019","journal-title":"J Mater Fetal Neonat Med"},{"key":"2025121400225998000_14.6.e083230.10","first-page":"74","article-title":"Does health care facility delivery reduces Puerperal sepsis? an analysis at a tertiary care hospital","volume":"12","author":"Hassan","year":"2022","journal-title":"J Soc Obstet Gynaecol Pak"},{"key":"2025121400225998000_14.6.e083230.11","doi-asserted-by":"crossref","first-page":"158","DOI":"10.24248\/eahrj.v4i2.639","article-title":"Factors and causes of Puerperal sepsis in Kilimanjaro, Tanzania: A descriptive study among postnatal women who attended Kilimanjaro Christian medical centre","volume":"4","author":"Kajeguka","year":"2020","journal-title":"East Afr Health Res J"},{"key":"2025121400225998000_14.6.e083230.12","unstructured":"Shatry D . Magnitude and risk factors for puerperal sepsis at the Pumwani maternity hospital, 2013;1\u201361, 2013. Available: http:\/\/www.erc.uonbi.ac.ke"},{"key":"2025121400225998000_14.6.e083230.13","doi-asserted-by":"crossref","DOI":"10.1186\/s12884-018-1891-1","article-title":"Incidence of postpartum infection, outcomes and associated risk factors at Mbarara regional referral hospital in Uganda","volume":"18","author":"Ngonzi","year":"2018","journal-title":"BMC Preg Child"},{"key":"2025121400225998000_14.6.e083230.14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/ijgo.13509","article-title":"The financial impact of Puerperal infections on patients, Carers and public hospitals in two regions in Ghana","volume":"154","author":"Fenny","year":"2021","journal-title":"Int J Gynaecol Obstet"},{"key":"2025121400225998000_14.6.e083230.15","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e14809","article-title":"Determinants of Puerperal sepsis among postpartum women at public hospitals of Hawassa city, Southern Ethiopia: institution-based unmatched case-control study","volume":"9","author":"Tesfaye","year":"2023","journal-title":"Heliyon"},{"key":"2025121400225998000_14.6.e083230.16","doi-asserted-by":"crossref","first-page":"190","DOI":"10.15406\/ipcb.2019.05.00175","article-title":"Puerperal sepsis and its associated factors among mothers in University of Gondar referral hospital, Ethiopia","volume":"5","author":"Atlaw","year":"2019","journal-title":"Int J Pregn & Chi Birth"},{"key":"2025121400225998000_14.6.e083230.17","doi-asserted-by":"crossref","DOI":"10.1186\/s13690-021-00732-y","article-title":"Burden of Puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis","volume":"79","author":"Melkie","year":"2021","journal-title":"Arch Public Health"},{"key":"2025121400225998000_14.6.e083230.18","first-page":"225","article-title":"Causes of maternal death in Ethiopia between 1990 and 2016: systematic review with meta-analysis","volume":"32","author":"Mekonnen","year":"2018","journal-title":"Ethiop J Heal Dev"},{"key":"2025121400225998000_14.6.e083230.19","doi-asserted-by":"crossref","DOI":"10.1186\/s40748-018-0086-0","article-title":"Magnitude and associated factors of postpartum morbidity in public health institutions of Debre Markos town, North","volume":"4","author":"Talie","year":"2018","journal-title":"Matern Health Neonatol Perinatol"},{"key":"2025121400225998000_14.6.e083230.20","doi-asserted-by":"crossref","DOI":"10.1186\/s12884-019-2230-x","article-title":"Determinants of Puerperal sepsis among post Partum women at public hospitals in West SHOA zone Oromia regional STATE, Ethiopia (institution BASEDCASE control study","volume":"19","author":"Demisse","year":"2019","journal-title":"BMC Preg Child"},{"key":"2025121400225998000_14.6.e083230.21","doi-asserted-by":"crossref","DOI":"10.1177\/17455065211067073","article-title":"Ethiopia\u2019s commitment towards achieving sustainable development goal on reduction of maternal mortality: there is a long way to go","volume":"17","author":"Ayele","year":"2021","journal-title":"Womens Health (Lond)"},{"key":"2025121400225998000_14.6.e083230.22","doi-asserted-by":"crossref","unstructured":"Mohammed A , Belay Y , Sintayehu Y , et al . Determinants of puerperal sepsis among postpartum women admitted to public and private hospitals in dire dawa city administration, eastern ethiopia: unmatched case- control study. In Review [Preprint] 2023. doi:10.21203\/rs.3.rs-2452884\/v1","DOI":"10.21203\/rs.3.rs-2452884\/v1"},{"key":"2025121400225998000_14.6.e083230.23","unstructured":"Central Statistical Agency . Population size by sex, region, zone and Wereda. 2022."},{"key":"2025121400225998000_14.6.e083230.24","doi-asserted-by":"crossref","DOI":"10.1186\/s12978-021-01103-0","article-title":"Incidence, causes, and Maternofetal outcomes of obstructed labor in Ethiopia: systematic review and meta - analysis","volume":"18","author":"Ayenew","year":"2021","journal-title":"Reprod Health"},{"key":"2025121400225998000_14.6.e083230.25","first-page":"1","article-title":"Determinants of Puerperal sepsis among post-Partum women at Finote Selam general hospital, West Gojjam zone, Amhara, Ethiopia","volume":"2","author":"Ayele","year":"2023","journal-title":"J Womens Health & Midwif Res"},{"key":"2025121400225998000_14.6.e083230.26","doi-asserted-by":"publisher","DOI":"10.2174\/1573399815666191024085838"},{"key":"2025121400225998000_14.6.e083230.27","unstructured":"Liben H , Tura G , Workneh D . Risk factors of Puerperal sepsis among mothers who gave birth in Jimma University specialized hospitaL, South West Ethiopia. 2016. 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