{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T10:45:45Z","timestamp":1784976345584,"version":"3.55.0"},"reference-count":46,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"unspecified","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["using the UK\u2019s Official Development Assistance"],"award-info":[{"award-number":["using the UK\u2019s Official Development Assistance"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["221940\/Z\/20\/Z"],"award-info":[{"award-number":["221940\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,4,29]]},"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Common mental health conditions (CMHCs), including depression, anxiety and post-traumatic stress disorder (PTSD), are highly prevalent in low and middle-income countries (LMICs). Preventive strategies combining psychological interventions with interventions addressing the social determinants of mental health may represent a key strategy for effectively preventing CMHCs. However, no systematic reviews have evaluated the effectiveness of these combined intervention strategies for preventing CMHCs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and analysis<\/jats:title>\n                  <jats:p>This systematic review will include randomised controlled trials (RCTs) focused on the effectiveness of interventions that combine preventive psychological interventions with interventions that address the social determinants of mental health in LMICs. Primary outcome is the frequency of depression, anxiety or PTSD at postintervention as determined by a formal diagnostic tool or any other standardised criteria. We will search Epistemonikos, Cochrane Controlled Trials Register (CENTRAL), MEDLINE, Embase, PsycINFO, CINAHL, Global Index Medicus, ClinicalTrials.gov (Ctgov), International Clinical Trials Registry Platform (ICTRP). Two reviewers will independently extract the data and evaluate the risk of bias of included studies using the Cochrane risk of bias tool 2. Random-effects meta-analyses will be performed, and certainty of evidence will be rated using the Grading of Recommendations Assessment, Development and Evaluation approach.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Ethics and dissemination<\/jats:title>\n                  <jats:p>This study uses data from published studies; therefore, ethical review is not required. Findings will be presented in a published manuscript.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>CRD42023451072<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-083261","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T02:26:25Z","timestamp":1715912785000},"page":"e083261","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Effectiveness of combining prevention psychological interventions with interventions that address the social determinants of mental health in low and middle-income countries: protocol of a systematic review and meta-analysis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4005-1967","authenticated-orcid":false,"given":"Eleonora","family":"Prina","sequence":"first","affiliation":[{"name":"WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9596-7622","authenticated-orcid":false,"given":"Beatrice","family":"Bano","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy"},{"name":"Faculty of Biomedical Sciences, Institute of Public Health, Universit\u00e0 della Svizzera Italiana, Lugano, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0016-6903","authenticated-orcid":false,"given":"Rakesh","family":"Singh","sequence":"additional","affiliation":[{"name":"Transcultural Psychosocial Organization (TPO) Nepal, Kathmandu, Bagmati, Nepal"},{"name":"Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiliano","family":"Albanese","sequence":"additional","affiliation":[{"name":"Faculty of Biomedical Sciences, Institute of Public Health, Universit\u00e0 della Svizzera Italiana, Lugano, Switzerland"},{"name":"Department of Psychiatry, University of Geneva, Geneve, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Trujillo","sequence":"additional","affiliation":[{"name":"Innovations for Poverty Action, Bogot\u00e0, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Cecilia","family":"Dedios Sanguineti","sequence":"additional","affiliation":[{"name":"School of Government, Universidad de Los Andes, Bogota, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Sorsdahl","sequence":"additional","affiliation":[{"name":"Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8291-0205","authenticated-orcid":false,"given":"Nagendra P","family":"Luitel","sequence":"additional","affiliation":[{"name":"Transcultural Psychosocial Organization (TPO) Nepal, Kathmandu, Bagmati, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily C","family":"Garman","sequence":"additional","affiliation":[{"name":"Alan J Flisher 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