{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:02:54Z","timestamp":1787508174718,"version":"build-2736575974"},"reference-count":72,"publisher":"BMJ","issue":"11","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"unspecified","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["NE 1635\/3-1"],"award-info":[{"award-number":["NE 1635\/3-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["TO 908\/2-1"],"award-info":[{"award-number":["TO 908\/2-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,10,22]]},"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Somatic symptom disorder (SSD) is a distressing mental disorder characterised by the presence of at least one persistent somatic symptom and a significant psychological burden due to the symptom(s), as well as excessive thoughts, feelings or behaviours related to them or associated health concerns. The primary aim of our study is to deepen the understanding of risk factors and mechanisms for somatic symptom persistence. Specifically, we will investigate the role of patients\u2019 expectations and somatic comorbidity regarding symptom persistence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>In a prospective 12-month cohort study, n=240 patients with SSD will be recruited from the outpatient clinics of the Department of Psychosomatic Medicine and Psychotherapy at the University Medical Center Hamburg-Eppendorf. The roles of two hypothesised predictors (ie, expectations and comorbidity) will be analysed together with known predisposing and maintaining factors of persistent somatic symptoms. The study entails macrolevel and microlevel assessments to investigate symptom severity over different timespans. Assessments at the macrolevel take place at baseline, 6 and 12 months. At the microlevel, a 10-day ecological momentary assessment study will be implemented to elucidate patients\u2019 dynamic experience with somatic symptoms in their natural environments. In order to elicit possible framing effects on the 10-day course of symptom severity, participants are randomised to either a positive or a negative expectation framing group. Cross-lagged panel models will be used to analyse data at the macrolevel. At the microlevel, multivariate latent growth curve models will be conducted to relate temporal changes in predictor and outcome variables to one another.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study was approved by the Ethics Committee of the Medical Associations Hamburg, Germany (2020-10197-BO-ff). The results will enable us to draw conclusions regarding the role of expectations for future targeted treatment options and regarding the utility of somatic comorbidity as a potential diagnostic specifier of SSD. Dissemination of our results will be achieved through scientific publications, and lay summaries for study participants, patient advocacy groups and the general public.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"isrctn\" xlink:href=\"ISRCTN36251388\">ISRCTN36251388<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2023-083500","type":"journal-article","created":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T21:55:33Z","timestamp":1731880533000},"page":"e083500","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Modifiable factors for somatic symptom persistence in patients with somatic symptom disorder: study protocol for a longitudinal cohort with an embedded ecologically momentary assessment (SOMA.SSD)"],"prefix":"10.1136","volume":"14","clinical-trial-number":[{"clinical-trial-number":"isrctn36251388","registry":"10.18810\/isrctn"},{"clinical-trial-number":"isrctn36251388","registry":"10.18810\/isrctn"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2191-0495","authenticated-orcid":false,"given":"Yvonne","family":"Nestoriuc","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6483-3456","authenticated-orcid":false,"given":"Franz","family":"Pauls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Blankenburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4175-248X","authenticated-orcid":false,"given":"Stefanie","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrike","family":"Wittenbecher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4220-3378","authenticated-orcid":false,"given":"Bernd","family":"L\u00f6we","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5189-6615","authenticated-orcid":false,"given":"Anne","family":"Toussaint","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,11,17]]},"reference":[{"key":"2024121219390953000_14.11.e083500.1","doi-asserted-by":"crossref","unstructured":"Association AP . Diagnostic and statistical manual of mental disorders. American Psychiatric Association, 2013.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"2024121219390953000_14.11.e083500.2","doi-asserted-by":"publisher","DOI":"10.1097\/psy.0000000000000588"},{"key":"2024121219390953000_14.11.e083500.3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-032813-153745"},{"key":"2024121219390953000_14.11.e083500.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2012.09.015"},{"key":"2024121219390953000_14.11.e083500.5","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000240"},{"key":"2024121219390953000_14.11.e083500.6","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1017\/S0033291717000149","article-title":"Medium- and long-term prognostic validity of competing classification proposals for the former somatoform disorders","volume":"47","author":"Schumacher","year":"2017","journal-title":"Psychol Med"},{"key":"2024121219390953000_14.11.e083500.7","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1017\/S0033291721004177","article-title":"Somatic symptom disorder: a scoping review on the empirical evidence of a new diagnosis","volume":"52","author":"L\u00f6we","year":"2022","journal-title":"Psychol Med"},{"key":"2024121219390953000_14.11.e083500.8","unstructured":"World Health Organization . International statistical classification of diseases and related health problems 10th. Geneva: World Health Organization, 2016."},{"key":"2024121219390953000_14.11.e083500.9","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/wps.20353","article-title":"Bodily distress disorder in ICD-11: problems and prospects","volume":"15","author":"Gureje","year":"2016","journal-title":"World Psychiatry"},{"key":"2024121219390953000_14.11.e083500.10","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jpsychores.2018.08.001","article-title":"Comparing the diagnostic concepts of ICD-10 somatoform disorders and DSM-5 somatic symptom disorders in patients from a psychosomatic outpatient clinic","volume":"113","author":"H\u00fcsing","year":"2018","journal-title":"J Psychosom Res"},{"key":"2024121219390953000_14.11.e083500.11","doi-asserted-by":"crossref","first-page":"152265","DOI":"10.1016\/j.comppsych.2021.152265","article-title":"Persistence rate of DSM-5 somatic symptom disorder: 4-year follow-up in patients from a psychosomatic outpatient clinic","volume":"110","author":"Behm","year":"2021","journal-title":"Compr Psychiatry"},{"key":"2024121219390953000_14.11.e083500.12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.genhosppsych.2017.07.002","article-title":"Monitoring somatic symptoms in patients with mental disorders: sensitivity to change and minimal clinically important difference of the Somatic Symptom Scale - 8 (SSS-8)","volume":"48","author":"Gierk","year":"2017","journal-title":"Gen Hosp Psychiatry"},{"key":"2024121219390953000_14.11.e083500.13","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.genhosppsych.2018.08.006","article-title":"Validity and sensitivity to change of the Somatic Symptom Disorder-B Criteria Scale (SSD-12) in a clinical population","volume":"55","author":"H\u00fcsing","year":"2018","journal-title":"Gen Hosp Psychiatry"},{"key":"2024121219390953000_14.11.e083500.14","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1097\/PSY.0000000000000786","article-title":"Validation of the Chinese Version of the Somatic Symptom Disorder-B Criteria Scale for Detecting DSM-5 Somatic Symptom Disorders: A Multicenter Study","volume":"82","author":"Li","year":"2020","journal-title":"Psychosom Med"},{"key":"2024121219390953000_14.11.e083500.15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jpsychores.2017.08.002","article-title":"Comparing the Patient Health Questionnaire \u2013 15 and the Somatic Symptom Scale \u2013 8 as measures of somatic symptom burden","volume":"101","author":"Toussaint","year":"2017","journal-title":"J Psychosom Res"},{"key":"2024121219390953000_14.11.e083500.16","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jpsychores.2017.03.017","article-title":"The Somatic Symptom Disorder - B Criteria Scale (SSD-12): Factorial structure, validity and population-based norms","volume":"97","author":"Toussaint","year":"2017","journal-title":"J Psychosom Res"},{"key":"2024121219390953000_14.11.e083500.17","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/PSY.0000000000001006","article-title":"Psychobiological Mechanisms in Somatic Symptom Disorder and Depressive Disorders: An Ecological Momentary Assessment Approach","volume":"84","author":"Mewes","year":"2022","journal-title":"Psychosom Med"},{"key":"2024121219390953000_14.11.e083500.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2018.01.006"},{"key":"2024121219390953000_14.11.e083500.19","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/sjop.12228","article-title":"The day-to-day concurrence of bodily complaints and affect in patients with severe somatoform disorder","volume":"56","author":"Houtveen","year":"2015","journal-title":"Scand J Psychol"},{"key":"2024121219390953000_14.11.e083500.20","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.biopsycho.2007.08.005","article-title":"Medically unexplained symptoms and between-group differences in 24-h ambulatory recording of stress physiology","volume":"76","author":"Houtveen","year":"2007","journal-title":"Biol Psychol"},{"key":"2024121219390953000_14.11.e083500.21","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-057596","article-title":"Persistent SOMAtic symptoms ACROSS diseases - from risk factors to modification: scientific framework and overarching protocol of the interdisciplinary SOMACROSS research unit (RU 5211)","volume":"12","author":"L\u00f6we","year":"2022","journal-title":"BMJ Open"},{"key":"2024121219390953000_14.11.e083500.22","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1016\/S0140-6736(24)00623-8","article-title":"Persistent physical symptoms: definition, genesis, and management","volume":"403","author":"L\u00f6we","year":"2024","journal-title":"The Lancet"},{"key":"2024121219390953000_14.11.e083500.23","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12916-016-0767-3","article-title":"Preoperative optimization of patient expectations improves long-term outcome in heart surgery patients: results of the randomized controlled PSY-HEART trial","volume":"15","author":"Rief","year":"2017","journal-title":"BMC Med"},{"key":"2024121219390953000_14.11.e083500.24","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-022-10089-2","article-title":"Preventing adverse events of chemotherapy for gastrointestinal cancer by educating patients about the nocebo effect: a randomized-controlled trial","volume":"22","author":"Michnevich","year":"2022","journal-title":"BMC Cancer"},{"key":"2024121219390953000_14.11.e083500.25","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/gerona\/62.3.281","article-title":"Methodology, design, and analytic techniques to address measurement of comorbid disease","volume":"62","author":"Lash","year":"2007","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2024121219390953000_14.11.e083500.26","doi-asserted-by":"crossref","first-page":"110108","DOI":"10.1016\/j.jpsychores.2020.110108","article-title":"Is severity a clinically meaningful specifier of somatic symptom disorder?","volume":"133","author":"Tu","year":"2020","journal-title":"J Psychosom Res"},{"key":"2024121219390953000_14.11.e083500.27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01935.x"},{"key":"2024121219390953000_14.11.e083500.28","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.genhosppsych.2018.10.004","article-title":"Somatic symptom disorder in the general population: associations with medical status and health care utilization using the SSD-12","volume":"56","author":"Kop","year":"2019","journal-title":"Gen Hosp Psychiatry"},{"key":"2024121219390953000_14.11.e083500.29","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.neubiorev.2020.02.007","article-title":"Heart rate variability in patients with somatic symptom disorders and functional somatic syndromes: A systematic review and meta-analysis","volume":"112","author":"Ying-Chih","year":"2020","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"2024121219390953000_14.11.e083500.30","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/PSY.0000000000000362","article-title":"Measures of Heart Rate Variability in Individuals With Somatic Symptom Disorder","volume":"79","author":"Huang","year":"2017","journal-title":"Psychosom Med"},{"key":"2024121219390953000_14.11.e083500.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2018.10.114"},{"key":"2024121219390953000_14.11.e083500.32","article-title":"Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults","volume":"2014","author":"van Dessel","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"2024121219390953000_14.11.e083500.33","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1159\/000501621","article-title":"Cognitive Behaviour Therapy Complemented with Emotion Regulation Training for Patients with Persistent Physical Symptoms: A Randomised Clinical Trial","volume":"88","author":"Kleinst\u00e4uber","year":"2019","journal-title":"Psychother Psychosom"},{"key":"2024121219390953000_14.11.e083500.34","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.112.121830"},{"key":"2024121219390953000_14.11.e083500.35","doi-asserted-by":"crossref","DOI":"10.1186\/s12888-019-2297-y","article-title":"Persistent physical symptoms reduction intervention: a system change and evaluation in secondary care (PRINCE secondary) - a CBT-based transdiagnostic approach: study protocol for a randomised controlled trial","volume":"19","author":"Chalder","year":"2019","journal-title":"BMC Psychiatry"},{"key":"2024121219390953000_14.11.e083500.36","doi-asserted-by":"crossref","first-page":"101829","DOI":"10.1016\/j.cpr.2020.101829","article-title":"Understanding persistent physical symptoms: conceptual integration of psychological expectation models and predictive processing accounts","volume":"76","author":"Kube","year":"2020","journal-title":"Clin Psychol Rev"},{"key":"2024121219390953000_14.11.e083500.37","doi-asserted-by":"crossref","unstructured":"Pezzulo G , Maisto D , Barca L , et al . Symptom Perception From a Predictive Processing Perspective. CPE 2019;1. doi:10.32872\/cpe.v1i4.35952","DOI":"10.32872\/cpe.v1i4.35952"},{"key":"2024121219390953000_14.11.e083500.38","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1159\/000484413","article-title":"Management of Functional Somatic Syndromes and Bodily Distress","volume":"87","author":"Henningsen","year":"2018","journal-title":"Psychother Psychosom"},{"key":"2024121219390953000_14.11.e083500.39","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3923"},{"key":"2024121219390953000_14.11.e083500.40","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2019.00504","article-title":"Minimizing Drug Adverse Events by Informing About the Nocebo Effect-An Experimental Study","volume":"10","author":"Pan","year":"2019","journal-title":"Front Psychiatry"},{"key":"2024121219390953000_14.11.e083500.41","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/acr.20160","article-title":"Prediction of nonspecific side effects in rheumatoid arthritis patients by beliefs about medicines","volume":"62","author":"Nestoriuc","year":"2010","journal-title":"Arthritis Care & Research"},{"key":"2024121219390953000_14.11.e083500.42","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2016.01876","article-title":"Can Psychological Expectation Models Be Adapted for Placebo Research?","volume":"7","author":"Rief","year":"2016","journal-title":"Front Psychol"},{"key":"2024121219390953000_14.11.e083500.43","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2407-13-426","article-title":"Optimizing expectations to prevent side effects and enhance quality of life in breast cancer patients undergoing endocrine therapy: study protocol of a randomized controlled trial","volume":"13","author":"von Blanckenburg","year":"2013","journal-title":"BMC Cancer"},{"key":"2024121219390953000_14.11.e083500.44","doi-asserted-by":"crossref","DOI":"10.32872\/cpe.v2i1.2695","article-title":"Optimizing Expectations About Endocrine Treatment for Breast Cancer: Results of the Randomized Controlled PSY-BREAST Trial","volume":"2","author":"Shedden-Mora","year":"2020","journal-title":"Clin Psychol Eur"},{"key":"2024121219390953000_14.11.e083500.45","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-018-4814-7","article-title":"Preventing adverse events of chemotherapy by educating patients about the nocebo effect (RENNO study) - study protocol of a randomized controlled trial with gastrointestinal cancer patients","volume":"18","author":"Quidde","year":"2018","journal-title":"BMC Cancer"},{"key":"2024121219390953000_14.11.e083500.46","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw266"},{"key":"2024121219390953000_14.11.e083500.47","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s10549-017-4637-2","article-title":"Facilitating adherence to endocrine therapy in breast cancer: stability and predictive power of treatment expectations in a 2-year prospective study","volume":"168","author":"Pan","year":"2018","journal-title":"Breast Cancer Res Treat"},{"key":"2024121219390953000_14.11.e083500.48","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1017\/S003329171900014X","article-title":"Detecting DSM-5 somatic symptom disorder: criterion validity of the Patient Health Questionnaire-15 (PHQ-15) and the Somatic Symptom Scale-8 (SSS-8) in combination with the Somatic Symptom Disorder - B Criteria Scale (SSD-12)","volume":"50","author":"Toussaint","year":"2020","journal-title":"Psychol Med"},{"key":"2024121219390953000_14.11.e083500.49","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD"},{"key":"2024121219390953000_14.11.e083500.50","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-158-3-201302050-00583"},{"key":"2024121219390953000_14.11.e083500.51","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-200203000-00008"},{"key":"2024121219390953000_14.11.e083500.52","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1097\/PSY.0000000000000502","article-title":"Core Outcome Domains for Clinical Trials on Somatic Symptom Disorder, Bodily Distress Disorder, and Functional Somatic Syndromes: European Network on Somatic Symptom Disorders Recommendations","volume":"79","author":"Rief","year":"2017","journal-title":"Psychosom Med"},{"key":"2024121219390953000_14.11.e083500.53","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000478028","article-title":"HCU-Q: Entwicklung eines Fragebogens zur Erfassung der Inanspruchnahme medizinischer Gesundheitsleistungen","volume":"28","author":"Weiss","year":"2018","journal-title":"Verhaltenstherapie"},{"key":"2024121219390953000_14.11.e083500.54","doi-asserted-by":"crossref","DOI":"10.2466\/pms.1984.59.3.974","article-title":"Preliminary validity study of the pain disability index","volume":"59","author":"Pollard","year":"1984","journal-title":"Percept Mot Skills"},{"key":"2024121219390953000_14.11.e083500.55","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.11.007"},{"key":"2024121219390953000_14.11.e083500.56","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(90)90068-O"},{"key":"2024121219390953000_14.11.e083500.57","first-page":"438","article-title":"The Pain Disability Index: psychometric and validity data","volume":"68","author":"Tait","year":"1987","journal-title":"Arch Phys Med Rehabil"},{"key":"2024121219390953000_14.11.e083500.58","unstructured":"Dillmann U , Nilges P , Saile H , et al . PDI - pain disability index - deutsche fassung: zpid (leibniz institute for psychology information) \u2013 testarchiv. 2011."},{"key":"2024121219390953000_14.11.e083500.59","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"2024121219390953000_14.11.e083500.60","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00109-7"},{"key":"2024121219390953000_14.11.e083500.61","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.pubmed.a024606"},{"key":"2024121219390953000_14.11.e083500.62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0280472","article-title":"The Treatment Expectation Questionnaire (TEX-Q): Validation of a generic multidimensional scale measuring patients\u2019 treatment expectations","volume":"18","author":"Shedden-Mora","year":"2023","journal-title":"PLoS One"},{"key":"2024121219390953000_14.11.e083500.63","unstructured":"Rief W , Nestoriuc Y , Mueller EM , et al . Generic rating scale for previous treatment experiences, treatment expectations, and treatment effects (GEEE). PsychArchives 2021."},{"key":"2024121219390953000_14.11.e083500.64","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1968.tb02103.x"},{"key":"2024121219390953000_14.11.e083500.65","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1111\/j.1365-2753.2010.01475.x","article-title":"The electronic Cumulative Illness Rating Scale: a reliable and valid tool to assess multi-morbidity in primary care","volume":"17","author":"Fortin","year":"2011","journal-title":"J Eval Clin Pract"},{"key":"2024121219390953000_14.11.e083500.66","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-009316","article-title":"Multimorbidity in elderly hospitalised patients and risk of Clostridium difficile infection: a retrospective study with the Cumulative Illness Rating Scale (CIRS)","volume":"5","author":"Ticinesi","year":"2015","journal-title":"BMJ Open"},{"key":"2024121219390953000_14.11.e083500.67","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2017.00213","article-title":"Heart Rate Variability and Cardiac Vagal Tone in Psychophysiological Research - Recommendations for Experiment Planning, Data Analysis, and Data Reporting","volume":"8","author":"Laborde","year":"2017","journal-title":"Front Psychol"},{"key":"2024121219390953000_14.11.e083500.68","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2022-067497","article-title":"Do expectations determine postoperative disability in women with endometriosis? Study protocol for a clinical mixed-methods observational cohort study","volume":"13","author":"Hirsing","year":"2023","journal-title":"BMJ Open"},{"key":"2024121219390953000_14.11.e083500.69","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1097\/PSY.0000000000000491","article-title":"Effectiveness of a Stepped, Collaborative, and Coordinated Health Care Network for Somatoform Disorders (Sofu-Net): A Controlled Cluster Cohort Study","volume":"79","author":"L\u00f6we","year":"2017","journal-title":"Psychosom Med"},{"key":"2024121219390953000_14.11.e083500.70","unstructured":"Selig JP , Little TD . Autoregressive and cross-lagged panel analysis for longitudinal data. In: Laursen B , Little TD , Card NA , eds. Handbook of developmental research methods. The Guilford Press, 2012: 265\u201378."},{"key":"2024121219390953000_14.11.e083500.71","doi-asserted-by":"publisher","DOI":"10.1177\/0091415016641692"},{"key":"2024121219390953000_14.11.e083500.72","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2019-035973","article-title":"Depression screening using patient-targeted feedback in general practices: study protocol of the German multicentre GET.FEEDBACK.GP randomised controlled trial","volume":"10","author":"Kohlmann","year":"2020","journal-title":"BMJ Open"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2023-083500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T22:59:07Z","timestamp":1734044347000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2023-083500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":72,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,17]]},"published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1136\/bmjopen-2023-083500"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2023-083500","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}