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Recent studies suggest that acoustic startle priming (ASP) tasks may enhance speech performance and motor initiation through the corticoreticulospinal tract. This has opened up new possibilities for the application of ASP in the rehabilitation of poststroke dysarthria. The aim of this study is to investigate whether ASP can improve rehabilitation outcomes in individuals with poststroke dysarthria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This prospective, randomised, controlled clinical trial plans to enrol 48 participants diagnosed with poststroke dysarthria. Participants will be randomly assigned to either the ASP group (n=24) or the control group (n=24). Both groups will undergo 30\u2009min of standard dysarthria rehabilitation training daily, 5\u2009days per week for 2 weeks. The ASP group will receive an additional 30\u2009min articulation training with ASP, while the control group will receive an equivalent 30\u2009min articulation training with normal acoustic stimuli. Speech and voice characteristics will be assessed using Frenchay Dysarthria Assessment, PRAAT software at baseline, 1\u2009week and 2 weeks postintervention. Furthermore, Functional Near Infrared Spectroscopy will be employed during ASP tasks to investigate cortical activation and changes in brain network connectivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study has been approved by the Tongji Hospital Medical Ethics Committee (TJ-IRB202312100). Raw data from this trial will be publicly available on the Public Management Platform for Clinical Research. The findings will be disseminated through international conferences and peer-reviewed journals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>ChiCTR2400081279.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2024-086791","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T05:40:17Z","timestamp":1753767617000},"page":"e086791","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of acoustic startle priming on poststroke dysarthria rehabilitation: study protocol for a double-blinded, single-centre randomised controlled trial in 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