{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T08:36:24Z","timestamp":1758962184410,"version":"3.43.0"},"reference-count":83,"publisher":"BMJ","issue":"2","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"unspecified","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"French National Institute of Cancer","award":["SHSESP 2017-130"],"award-info":[{"award-number":["SHSESP 2017-130"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,12,10]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Women with higher educational attainment have a higher risk of developing breast cancer (BC). Despite the acknowledged impact of reproductive and lifestyle factors, some excess risks remain unexplained. Many studies support the hypothesis that education has a distinctive effect on physiological processes associated with health, independently of known risk factors.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Objectives<\/jats:title>\n<jats:p>In this study, we aimed to determine whether the biological embodiment of education could be part of the observed social inequalities in BC risk. We focused on biomarkers from several physiological systems examined individually, and jointly through a biological health score (BHS).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Design<\/jats:title>\n<jats:p>Prospective cohort study.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Setting<\/jats:title>\n<jats:p>This study, based on a subsample of the French E3N cohort, included women with biological data from four nested case\u2013control studies.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Participants<\/jats:title>\n<jats:p>The study included 3048 postmenopausal women (17% BC).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Main outcome measures<\/jats:title>\n<jats:p>We first evaluated the association between educational attainment and each biomarker, separately (N=11) and by combining them into a BHS, indicative of an augmented biological health hazard when elevated. Finally, we explored the relationships between the socially patterned biomarkers and BHS, and risk of incident BC.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>\nWomen with higher educational attainment exhibited a lower BHS in comparison to those with lower educational attainment (\u03b2\n<jats:sub>high education<\/jats:sub>\n=\u22120.21 (95% CI \u22120.42; 0.01), model 2). Specific biomarkers associated with the cardiovascular (systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides (TG), high-density lipoprotein (HDL)), inflammatory (C reactive protein (CRP)) and hormonal systems (sex hormone-binding globulin (SHBG) and oestradiol) were found socially distributed (OR\n<jats:sub>CRP-high<\/jats:sub>\n=0.70 (95% CI 0.54; 0.91), OR\n<jats:sub>TG-high<\/jats:sub>\n=0.79 (95% CI 0.61; 1.04), OR\n<jats:sub>DBP-high<\/jats:sub>\n=0.69 (95% CI 0.53; 0.90), OR\n<jats:sub>SBP-high<\/jats:sub>\n=0.57 (95% CI 0.44; 0.74), OR\n<jats:sub>HDL-high<\/jats:sub>\n=0.79 (95% CI 0.60; 1.03), (OR\n<jats:sub>SHBG-high<\/jats:sub>\n=0.67 (95% CI 0.52; 0.88), OR\n<jats:sub>oestradiol-high<\/jats:sub>\n=1.34 (95% CI 1.00; 1.79); model 1). Associations persisted after adjustment for cofounders and a large set of potential mediators for two of the investigated cardiovascular markers (OR\n<jats:sub>DBP-high<\/jats:sub>\n=0.75 (95% CI 0.57; 1.00), OR\n<jats:sub>SBP-high<\/jats:sub>\n=0.61 (95% CI 0.46; 0.81); model 2). No associations were found between the socially stratified biomarkers and BHS with risk of BC.\n<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Educational attainment has a direct impact on biological processes suggesting that the biological embodiment of the social environment could be a potential pathway that mediates the association between educational attainment and health. Further studies are needed to specifically investigate the relationships between socially stratified biomarkers and BC risk.<\/jats:p>\n<\/jats:sec>","DOI":"10.1136\/bmjopen-2024-087537","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T10:44:02Z","timestamp":1738925042000},"page":"e087537","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort"],"prefix":"10.1136","volume":"15","clinical-trial-number":[{"clinical-trial-number":"nct03285230","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Elo\u00efse","family":"Berger","sequence":"first","affiliation":[{"name":"EQUITY team, INSERM-UMR 1295, CERPOP, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8248-497X","authenticated-orcid":false,"given":"Richard","family":"Dudouet","sequence":"additional","affiliation":[{"name":"EQUITY team, INSERM-UMR 1295, CERPOP, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Dossus","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Baglietto","sequence":"additional","affiliation":[{"name":"Paris Saclay University, INSERM, Gustave Roussy, 'Exposome and Heredity' Team, CESP, UVSQ, Villejuif, France"},{"name":"Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amandine","family":"Gelot","sequence":"additional","affiliation":[{"name":"Paris Saclay University, INSERM, Gustave Roussy, 'Exposome and Heredity' Team, CESP, UVSQ, Villejuif, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Christine","family":"Boutron-Ruault","sequence":"additional","affiliation":[{"name":"Paris Saclay University, INSERM, Gustave Roussy, 'Exposome and Heredity' Team, CESP, UVSQ, Villejuif, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Severi","sequence":"additional","affiliation":[{"name":"Paris Saclay University, INSERM, Gustave Roussy, 'Exposome and Heredity' Team, CESP, UVSQ, Villejuif, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rapha\u00eble","family":"Castagn\u00e9","sequence":"additional","affiliation":[{"name":"EQUITY team, INSERM-UMR 1295, CERPOP, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrille","family":"Delpierre","sequence":"additional","affiliation":[{"name":"EQUITY team, INSERM-UMR 1295, CERPOP, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"2025070104270778000_15.2.e087537.1","unstructured":"Hvidtfeldt UA . Mechanisms underlying social inequality in post-menopausal breast cancer. Dan Med J 2014;61."},{"key":"2025070104270778000_15.2.e087537.2","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckw070"},{"key":"2025070104270778000_15.2.e087537.3","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23007"},{"key":"2025070104270778000_15.2.e087537.4","doi-asserted-by":"publisher","DOI":"10.1177\/0898264311422744"},{"key":"2025070104270778000_15.2.e087537.5","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20952"},{"key":"2025070104270778000_15.2.e087537.6","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20203"},{"key":"2025070104270778000_15.2.e087537.7","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-020-07648-w","article-title":"The impact of lifecourse socio-economic position and individual social mobility on breast cancer risk","volume":"20","author":"Berger","year":"2020","journal-title":"BMC Cancer"},{"key":"2025070104270778000_15.2.e087537.8","doi-asserted-by":"crossref","first-page":"112781","DOI":"10.1016\/j.socscimed.2019.112781","article-title":"Health inequalities: Embodied evidence across biological layers","volume":"246","author":"Vineis","year":"2020","journal-title":"Soc Sci Med"},{"key":"2025070104270778000_15.2.e087537.9","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1146\/annurev-soc-060116-053339","article-title":"Integrating Biomarkers in Social Stratification and Health Research","volume":"44","author":"Harris","year":"2018","journal-title":"Annu Rev Sociol"},{"key":"2025070104270778000_15.2.e087537.10","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410180039004"},{"key":"2025070104270778000_15.2.e087537.11","doi-asserted-by":"crossref","first-page":"79","DOI":"10.14301\/llcs.v7i1.325","article-title":"Origins of heath inequalities: the case for Allostatic Load","volume":"7","author":"Delpierre","year":"2016","journal-title":"LLCS"},{"key":"2025070104270778000_15.2.e087537.12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08103.x"},{"key":"2025070104270778000_15.2.e087537.13","doi-asserted-by":"publisher","DOI":"10.1159\/000510696"},{"key":"2025070104270778000_15.2.e087537.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2017.09.025"},{"key":"2025070104270778000_15.2.e087537.15","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/jech-2018-212010","article-title":"Early-life inequalities and biological ageing: a multisystem Biological Health Score approach in U nderstanding S ociety","volume":"73","author":"Karimi","year":"2019","journal-title":"J Epidemiol Community Health Ao\u00fbt"},{"key":"2025070104270778000_15.2.e087537.16","doi-asserted-by":"crossref","unstructured":"Neufcourt L , Castagn\u00e9 R , Wilsgaard T , et al . Educational patterning in biological health seven years apart: Findings from the Troms\u00f8 Study. Psychoneuroendocrinology 2024;160. doi:10.1016\/j.psyneuen.2023.106670","DOI":"10.1016\/j.psyneuen.2023.106670"},{"key":"2025070104270778000_15.2.e087537.17","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08732-x"},{"key":"2025070104270778000_15.2.e087537.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2020.09.002"},{"key":"2025070104270778000_15.2.e087537.19","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-37440-7","article-title":"A Comparative Analysis of the Status Anxiety Hypothesis of Socio-economic Inequalities in Health Based on 18,349 individuals in Four Countries and Five Cohort Studies","volume":"9","author":"Layte","year":"2019","journal-title":"Sci Rep"},{"key":"2025070104270778000_15.2.e087537.20","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-7-212","article-title":"Socioeconomic and racial\/ethnic differentials of C-reactive protein levels: a systematic review of population-based studies","volume":"7","author":"Nazmi","year":"2007","journal-title":"BMC Public Health"},{"key":"2025070104270778000_15.2.e087537.21","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/abm\/kaac004","article-title":"Systemic Inflammation Contributes to the Association Between Childhood Socioeconomic Disadvantage and Midlife Cardiometabolic Risk","volume":"57","author":"Natale","year":"2023","journal-title":"Ann Behav Med"},{"key":"2025070104270778000_15.2.e087537.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107164"},{"key":"2025070104270778000_15.2.e087537.23","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/ajh\/hpab029","article-title":"Life Course Socioeconomic Position, Intergenerational Social Mobility, and Hypertension Incidence in ELSA-Brasil","volume":"34","author":"Lopes","year":"2021","journal-title":"Am J Hypertens"},{"key":"2025070104270778000_15.2.e087537.24","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1093\/gerona\/glab280","article-title":"Childhood Socioeconomic Status and Cardiometabolic Health: A Test of the John Henryism Hypothesis in African American Older Adults","volume":"77","author":"Zilioli","year":"2022","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2025070104270778000_15.2.e087537.25","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-11-139","article-title":"Associations of education with 30 year life course blood pressure trajectories: Framingham Offspring Study","volume":"11","author":"Loucks","year":"2011","journal-title":"BMC Public Health"},{"key":"2025070104270778000_15.2.e087537.26","doi-asserted-by":"crossref","DOI":"10.1016\/j.ssmph.2020.100634","article-title":"Race\/ethnicity, neighborhood socioeconomic status and cardio-metabolic risk","volume":"11","author":"Merkin","year":"2020","journal-title":"SSM Popul Health"},{"key":"2025070104270778000_15.2.e087537.27","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-022-13158-0","article-title":"Evaluating the association between socioeconomic position and cardiometabolic risk markers in young adulthood by different life course models","volume":"22","author":"Kempel","year":"2022","journal-title":"BMC Public Health"},{"key":"2025070104270778000_15.2.e087537.28","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyaa188"},{"key":"2025070104270778000_15.2.e087537.29","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.socscimed.2015.11.001","article-title":"Socioeconomic conditions across life related to multiple measures of the endocrine system in older adults: Longitudinal findings from a British birth cohort study","volume":"147","author":"Bann","year":"2015","journal-title":"Social Science & Medicine"},{"key":"2025070104270778000_15.2.e087537.30","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1399"},{"key":"2025070104270778000_15.2.e087537.31","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.metabol.2016.05.011","article-title":"Clinical correlates of sex hormones in women: The study of health in Pomerania","volume":"65","author":"Kische","year":"2016","journal-title":"Metab Clin Exp"},{"key":"2025070104270778000_15.2.e087537.32","doi-asserted-by":"publisher","DOI":"10.1097\/NNR.0000000000000096"},{"key":"2025070104270778000_15.2.e087537.33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/1874091X01711010001","article-title":"Socioeconomic Deprivation as Measured by the Index of Multiple Deprivation and Its Association with Low Sex Hormone Binding Globulin in Women","volume":"11","author":"Heald","year":"2017","journal-title":"Open Biochem J"},{"key":"2025070104270778000_15.2.e087537.34","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14133044","article-title":"Association of Allostatic Load and All Cancer Risk in the SWAN Cohort","volume":"14","author":"Shen","year":"2022","journal-title":"Cancers (Basel)"},{"key":"2025070104270778000_15.2.e087537.35","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29935"},{"key":"2025070104270778000_15.2.e087537.36","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.13989","article-title":"Association of Allostatic Load With All-Cause Mortality in Patients With Breast Cancer","volume":"6","author":"Obeng-Gyasi","year":"2023","journal-title":"JAMA Netw Open"},{"key":"2025070104270778000_15.2.e087537.37","doi-asserted-by":"crossref","DOI":"10.1038\/srep10508","article-title":"C-reactive protein and risk of breast cancer: A systematic review and meta-analysis","volume":"5","author":"Guo","year":"2015","journal-title":"Sci Rep"},{"key":"2025070104270778000_15.2.e087537.38","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0324"},{"key":"2025070104270778000_15.2.e087537.39","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451500183X"},{"key":"2025070104270778000_15.2.e087537.40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0142669","article-title":"Serum Lipids and Breast Cancer Risk: A Meta-Analysis of Prospective Cohort Studies","volume":"10","author":"Ni","year":"2015","journal-title":"PLoS ONE"},{"key":"2025070104270778000_15.2.e087537.41","doi-asserted-by":"crossref","DOI":"10.1038\/srep44877","article-title":"Hypertension and breast cancer risk: a systematic review and meta-analysis","volume":"7","author":"Han","year":"2017","journal-title":"Sci Rep"},{"key":"2025070104270778000_15.2.e087537.42","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-45014-4","article-title":"Association between blood pressure and risk of cancer development: a systematic review and meta-analysis of observational studies","volume":"9","author":"Seretis","year":"2019","journal-title":"Sci Rep"},{"key":"2025070104270778000_15.2.e087537.43","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-4_Part_1-199902160-00004"},{"key":"2025070104270778000_15.2.e087537.44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2007.05.012"},{"key":"2025070104270778000_15.2.e087537.45","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-11-0090"},{"key":"2025070104270778000_15.2.e087537.46","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.8.606"},{"key":"2025070104270778000_15.2.e087537.47","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-0808"},{"key":"2025070104270778000_15.2.e087537.48","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009059"},{"key":"2025070104270778000_15.2.e087537.49","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-012-2391-z"},{"key":"2025070104270778000_15.2.e087537.50","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1055\/s-0034-1395606","article-title":"Sex hormone binding globulin and risk of breast cancer in postmenopausal women: a meta-analysis of prospective studies","volume":"47","author":"He","year":"2015","journal-title":"Horm Metab Res"},{"key":"2025070104270778000_15.2.e087537.51","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu184"},{"key":"2025070104270778000_15.2.e087537.52","doi-asserted-by":"publisher","DOI":"10.1079\/PHN2002394"},{"key":"2025070104270778000_15.2.e087537.53","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-014-0355-9"},{"key":"2025070104270778000_15.2.e087537.54","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-10-0264"},{"key":"2025070104270778000_15.2.e087537.55","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v045.i05"},{"key":"2025070104270778000_15.2.e087537.56"},{"key":"2025070104270778000_15.2.e087537.57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0177151","article-title":"Socio-economic status over the life course and obesity: Systematic review and meta-analysis","volume":"12","author":"Newton","year":"2017","journal-title":"PLoS ONE"},{"key":"2025070104270778000_15.2.e087537.58","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-8902.2003.0342.x"},{"key":"2025070104270778000_15.2.e087537.59","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12003"},{"key":"2025070104270778000_15.2.e087537.60","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s13679-023-00518-z","article-title":"Obesity and Dyslipidemia: A Review of Current Evidence","volume":"12","author":"Vekic","year":"2023","journal-title":"Curr Obes Rep"},{"key":"2025070104270778000_15.2.e087537.61","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.cca.2021.06.029","article-title":"Pathology of metabolically-related dyslipidemia","volume":"521","author":"Su","year":"2021","journal-title":"Clin Chim Acta"},{"key":"2025070104270778000_15.2.e087537.62","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2010.9"},{"key":"2025070104270778000_15.2.e087537.63","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2019.12.03"},{"key":"2025070104270778000_15.2.e087537.64","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djg022"},{"key":"2025070104270778000_15.2.e087537.65","doi-asserted-by":"crossref","DOI":"10.1177\/2045894020952023","article-title":"Obesity, estrogens and adipose tissue dysfunction - implications for pulmonary arterial hypertension","volume":"10","author":"Mair","year":"2020","journal-title":"Pulm Circ"},{"key":"2025070104270778000_15.2.e087537.66","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyh381"},{"key":"2025070104270778000_15.2.e087537.67","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05331.x"},{"key":"2025070104270778000_15.2.e087537.68","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1467-985X.2006.00411.x","article-title":"Pathways Between Education and Health: A Causal Modelling Approach","volume":"169","author":"Chandola","year":"2006","journal-title":"J R Stat Soc Ser A Stat Soc"},{"key":"2025070104270778000_15.2.e087537.69","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.2002.00798.x"},{"key":"2025070104270778000_15.2.e087537.70","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1127\/anthranz\/62\/2004\/311","article-title":"Testosterone levels and stress in women: the role of stress coping strategies, anxiety and sex role identification","volume":"62","author":"Kunstmann","year":"2004","journal-title":"Anthranz"},{"key":"2025070104270778000_15.2.e087537.71","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-200205000-00015"},{"key":"2025070104270778000_15.2.e087537.72","doi-asserted-by":"publisher","DOI":"10.1530\/REP-16-0404"},{"key":"2025070104270778000_15.2.e087537.73","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2012.06569.x"},{"key":"2025070104270778000_15.2.e087537.74","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-019-0487-5","article-title":"Testosterone imbalance may link depression and increased body weight in premenopausal women","volume":"9","author":"Stanikova","year":"2019","journal-title":"Transl Psychiatry"},{"key":"2025070104270778000_15.2.e087537.75","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2023.107817"},{"key":"2025070104270778000_15.2.e087537.76","doi-asserted-by":"crossref","DOI":"10.1186\/s13058-023-01754-w","article-title":"Association between allostatic load and breast cancer risk: a cohort study","volume":"25","author":"Guan","year":"2023","journal-title":"Breast Cancer Res"},{"key":"2025070104270778000_15.2.e087537.77","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-20301-6_3"},{"key":"2025070104270778000_15.2.e087537.78","unstructured":"Niveau d\u2019\u00e9ducation de la population \u2212 france, portrait social. 2020. Available: https:\/\/www.insee.fr\/fr\/statistiques\/4797586?sommaire=4928952#tableau-figure2"},{"key":"2025070104270778000_15.2.e087537.79","unstructured":"La proportion de bacheliers dans une g\u00e9n\u00e9ration. 1995. Available: https:\/\/data.education.gouv.fr\/explore\/dataset\/fr-en-proportion-de-bacheliers-dans-une-generation\/"},{"key":"2025070104270778000_15.2.e087537.80","first-page":"969","article-title":"Intraindividual variability over time in plasma biomarkers of inflammation and effects of long-term storage","volume":"25","author":"Hardikar","year":"2014","journal-title":"Cancer Causes Control"},{"key":"2025070104270778000_15.2.e087537.81","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-010-9572-z"},{"key":"2025070104270778000_15.2.e087537.82","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2000.1336"},{"key":"2025070104270778000_15.2.e087537.83","doi-asserted-by":"crossref","DOI":"10.1177\/10732748211011956","article-title":"Factors Explaining Socio-Economic Inequalities in Cancer Survival: A Systematic Review","volume":"28","author":"Afshar","year":"2021","journal-title":"Cancer Control"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2024-087537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T15:54:42Z","timestamp":1754495682000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2024-087537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":83,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,26]]},"published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1136\/bmjopen-2024-087537"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2024-087537","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2025,2]]}}}