{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T14:59:13Z","timestamp":1793026753686,"version":"4.5.0"},"reference-count":30,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"unspecified","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"TUA Research Funding","award":["TUAGBG-919531"],"award-info":[{"award-number":["TUAGBG-919531"]}]},{"name":"TUA Research Funding","award":["TUAGBG-979382"],"award-info":[{"award-number":["TUAGBG-979382"]}]},{"name":"Eklund Foundation","award":["2018-132"],"award-info":[{"award-number":["2018-132"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,6,14]]},"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the association between type 1 diabetes (T1D)\/type 2 diabetes (T2D) and periodontitis and assess the influence of periodontitis on diabetes-related complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Observational study; longitudinal analysis of register data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Swedish primary care centres, hospitals and dental clinics reporting to nationwide healthcare registers (2010\u20132020).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>28 801 individuals with T1D (13 022\u2009women; mean age 42 years) and 57 839 individuals without diabetes (non-T1D; 26 271\u2009women; mean age 43 years). 251 645 individuals with T2D (110 627\u2009women; mean age 61 years) and 539 805 individuals without diabetes (non-T2D; 235 533\u2009women; mean age 60 years). Diabetes and non-diabetes groups were matched for age, gender and county of residence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Prevalent periodontitis, diabetes-related complications (retinopathy, albuminuria, stroke and ischaemic heart disease) and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Periodontitis was more common among T2D (22%) than non-T2D (17%). Differences were larger in younger age groups (adjusted RR at age 30\u201339 years 1.92; 95% CI 1.81 to 2.03) and exacerbated by poor glycaemic control. Periodontitis prevalence was 13% in T1D and 11% in non-T1D; only the subgroup with poor glycaemic control was at higher risk for periodontitis. Periodontitis was associated with a higher incidence of retinopathy (T1D: HR 1.08, 95% CI 1.02 to 1.14; T2D: HR 1.08, 95% CI 1.06 to 1.10) and albuminuria (T1D: HR 1.14, 95% CI 1.06 to 1.23; T2D: HR 1.09, 95% CI 1.07 to 1.11). Periodontitis was not associated with a higher risk for stroke, cardiovascular disease or higher mortality in T1D\/T2D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The association between T2D and periodontitis was strong and exacerbated by poor glycaemic control. For T1D, the association to periodontitis was limited to subgroups with poor glycaemic control. Periodontitis contributed to an increased risk for retinopathy and albuminuria in T1D and T2D.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2024-087557","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T12:30:46Z","timestamp":1720096246000},"page":"e087557","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":22,"title":["Periodontitis in patients with diabetes and its association with diabetes-related complications. 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