{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:04:29Z","timestamp":1790258669317,"version":"4.1.0"},"reference-count":33,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"unspecified","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2024,12,13]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Sedentary behaviour (SB) is associated with increased risks of breast, colorectal, endometrial, ovarian and rectal cancers. However, the number of cancer cases attributable to SB in Germany and the associated costs are unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Numbers and proportions (population-attributable fractions, PAF) of new cancer cases attributable to SB with published risk estimates for Germany for the years 2024, 2030 and 2040.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Sex-specific and age-specific population projections, national cancer incidence and exposure data. Primary and secondary outcome measures: new cancer cases attributable to SB and healthcare costs associated with cancer cases attributable to SB in Germany for the year 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Estimated numbers of cancers attributable to SB are projected to be up to 7612 cases (6% of total cancer cases) in 2024, up to 7899 cases (6%) in 2030 and up to 8245 cases (6%) in 2040. The PAF attributable to SB in women is 3% for breast cancer, 8% for colon cancer, 9% for both endometrial and ovarian cancers and 2% for rectal cancer. In men, the PAF is 9% for colon cancer and 3% for rectal cancer. In 2024, the estimated costs of SB-attributable cancers are \u20ac270\u2009million for colon cancer, \u20ac51\u2009million for rectal cancer, \u20ac234\u2009million for breast cancer and \u20ac242\u2009million for female genital cancers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A considerable number of cancer cases can be attributed to SB, which also imposes a large health economic burden. Implementing effective prevention measures, such as workplace, school or commuting interventions, is needed to reduce the incidence of cancer attributable to this modifiable risk factor.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2024-094304","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T21:55:36Z","timestamp":1736891736000},"page":"e094304","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data"],"prefix":"10.1136","volume":"15","author":[{"given":"Katharina","family":"Schaber","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Leitzmann","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Pukrop","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany"},{"name":"Bavarian Cancer Research Center (BZKF), Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilm","family":"Quentin","sequence":"additional","affiliation":[{"name":"Department of Planetary & Public Health, University of Bayreuth, Bayreuth, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1120-1751","authenticated-orcid":false,"given":"Michael J","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2741-3759","authenticated-orcid":false,"given":"Carmen","family":"Jochem","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany"},{"name":"Department of Planetary & Public Health, University of Bayreuth, Bayreuth, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,1,14]]},"reference":[{"key":"2025081403170057000_15.1.e094304.1","doi-asserted-by":"crossref","DOI":"10.1186\/s12966-017-0525-8","article-title":"Sedentary Behavior Research Network (SBRN) - Terminology Consensus Project process and outcome","volume":"14","author":"Tremblay","year":"2017","journal-title":"Int J Behav Nutr Phys Act"},{"key":"2025081403170057000_15.1.e094304.2","doi-asserted-by":"crossref","unstructured":"Ahrensberg H , Bj\u00f8rk Petersen C , Jacobsen JNW , et al . 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