{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:57:59Z","timestamp":1767193079775,"version":"3.48.0"},"reference-count":14,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2025,8,9]],"date-time":"2025-08-09T00:00:00Z","timestamp":1754697600000},"content-version":"unspecified","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012880"],"award-info":[{"award-number":["2024A1515012880"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,7,31]]},"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Erector spinae plane (ESP) block and local infiltration analgesia (LIA) are widely used to control postoperative pain after abdominal surgery. An increasing number of randomised controlled trials (RCTs) have compared the analgesic effects of ESP block and LIA after abdominal surgery, but the results are inconsistent. This protocol of a systematic review and meta-analysis aims to determine whether the analgesic effects of ESP block are better than those of LIA in abdominal surgeries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>Two authors will independently search PubMed, EMBASE, Web of Science and the Cochrane Library from their inception to 15 August 2025. RCTs that compared the analgesic effects of ESP block with LIA for abdominal surgeries will be included. The primary outcome will be opioid consumption over 24 hours postoperatively. The secondary outcomes will include the time to first rescue analgesia, pain intensity score and incidence of adverse effects. RevMan V.5.4 software will be used for statistical analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethical approval is not applicable. The results of this study will be publicly published in one peer-reviewed journal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42024598176.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2024-095295","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T02:35:54Z","timestamp":1754879754000},"page":"e095295","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of erector spinae plane block versus local infiltration analgesia for abdominal surgeries: a protocol for systematic review and meta-analysis"],"prefix":"10.1136","volume":"15","author":[{"given":"Feng","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Shenzhen Longgang Second People\u2019s Hospital, Shenzhen, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoujia","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People\u2019s Hospital of Shenzhen, Shenzhen, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2754-7204","authenticated-orcid":false,"given":"Yiyong","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Longgang Maternity and Child Institute of Shantou University Medical College (Longgang District Maternity & Child Healthcare Hospital of Shenzhen City), Shenzhen, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,8,10]]},"reference":[{"key":"2025123106460521000_15.8.e095295.1","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.812531","article-title":"Erector Spinae Plane Block in Abdominal Surgery: A Meta-Analysis","volume":"9","author":"Viderman","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"2025123106460521000_15.8.e095295.2","doi-asserted-by":"crossref","DOI":"10.1007\/s11916-021-00945-4","article-title":"Regional Anesthesia Abdominal Blocks and Local Infiltration After Cesarean Delivery: Review of Current Evidence","volume":"25","author":"Gabriel","year":"2021","journal-title":"Curr Pain Headache Rep"},{"doi-asserted-by":"publisher","key":"2025123106460521000_15.8.e095295.3","DOI":"10.1016\/j.bja.2022.05.029"},{"key":"2025123106460521000_15.8.e095295.4","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.1111\/anae.14868","article-title":"Advances in regional anaesthesia and acute pain management: a narrative review","volume":"75","author":"Albrecht","year":"2020","journal-title":"Anaesthesia"},{"key":"2025123106460521000_15.8.e095295.5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0209646","article-title":"Dexamethasone added to local anesthetics in ultrasound-guided transversus abdominis plain (TAP) block for analgesia after abdominal surgery: A systematic review and meta-analysis of randomized controlled trials","volume":"14","author":"Zhang","year":"2019","journal-title":"PLoS ONE"},{"doi-asserted-by":"publisher","key":"2025123106460521000_15.8.e095295.6","DOI":"10.1016\/j.jclinane.2018.09.036"},{"doi-asserted-by":"publisher","key":"2025123106460521000_15.8.e095295.7","DOI":"10.1002\/bjs.9204"},{"key":"2025123106460521000_15.8.e095295.8","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1002\/ejp.1181","article-title":"Effect of local wound infiltration with ketamine versus dexmedetomidine on postoperative pain and stress after abdominal hysterectomy, a randomized trial","volume":"22","author":"Mohamed","year":"2018","journal-title":"Eur J Pain"},{"key":"2025123106460521000_15.8.e095295.9","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000039054","article-title":"Comparison of the postoperative effects of the erector spinae plane block and local infiltration analgesia in patients operated with lumbotomy surgery incision: Randomized clinical study","volume":"103","author":"Hakimo\u011flu","year":"2024","journal-title":"Medicine (Baltimore)"},{"key":"2025123106460521000_15.8.e095295.10","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4103\/ija.IJA_1450_20","article-title":"Comparison of erector spinae plane block and local anaesthetic infiltration of the incision site for postoperative analgesia in percutaneous nephrolithotomy - A randomised parallel-group study","volume":"65","author":"Ramachandran","year":"2021","journal-title":"Indian J Anaesth"},{"key":"2025123106460521000_15.8.e095295.11","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.redar.2022.11.007","article-title":"Erector spinae plane block versus local infiltration anaesthesia for transforaminal percutaneous endoscopic discectomy: A prospective randomised controlled trial","volume":"70","author":"Barsa","year":"2023","journal-title":"Rev Esp Anestesiol Reanim (Engl Ed)"},{"key":"2025123106460521000_15.8.e095295.12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.23736\/S0375-9393.22.15950-X","article-title":"Bilateral lumbar ultrasound-guided erector spinae plane block versus local anesthetic infiltration for perioperative analgesia in lumbar spine surgery: a randomized controlled trial","volume":"88","author":"Vergari","year":"2022","journal-title":"Minerva Anestesiol"},{"key":"2025123106460521000_15.8.e095295.13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1186\/s12871-021-01474-8","article-title":"A comparison of ultrasound guided bilateral single injection shot Erector Spinae Plane blocks versus wound infiltration for post-operative analgesia in laparoscopic assisted colonic surgery- a prospective randomised study","volume":"21","author":"Rao Kadam","year":"2021","journal-title":"BMC Anesthesiol"},{"key":"2025123106460521000_15.8.e095295.14","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.29271\/jcpsp.2019.12.1138","article-title":"Comparison of the Effects of Ultrasound-guided Erector Spinae Plane Block and Wound Infiltration on Perioperative Opioid Consumption and Postoperative Pain in Thoracotomy","volume":"29","author":"Wang","year":"2019","journal-title":"J Coll Physicians Surg Pak"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2024-095295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:47:02Z","timestamp":1767192422000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2024-095295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":14,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,10]]},"published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1136\/bmjopen-2024-095295"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2024-095295","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2025,8]]}}}