{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:28:16Z","timestamp":1783351696971,"version":"3.54.6"},"reference-count":54,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"unspecified","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"NA"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,10,10]]},"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To explore the levels of health-related functioning during pregnancy and postpartum and its association with non-severe maternal morbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>An observational longitudinal study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>A tertiary women\u2019s hospital in urban China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Pregnant women in late pregnancy were recruited via consecutive sampling. The Chinese version of the Women\u2019s Outcome Instrument for maternal healthCarE instrument was applied to measure health-related functioning and maternal morbidities at 28\u201341.6 weeks of gestation and at 6 weeks postpartum. Main outcome measures included health-related functioning, physical symptoms, anxiety and depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 624 participants, health-related functioning scores were significantly higher during late pregnancy than at 6 weeks postpartum (16.33\u00b14.78 vs 14.40\u00b13.65, p&lt;0.001), reflected by a marked reduction in the prevalence of severe functional impairment (from 20.5% to 11.2%). Multivariate analyses revealed that antenatal impairment was significantly associated with moderately high physical symptoms (aOR=3.618, 95%\u2009CI 1.061 to 12.354, p&lt;0.05), mild to moderate anxiety (mild: aOR=2.986, 95%\u2009CI 1.318 to 6.767, p&lt;0.01; moderate: aOR=7.250, 95%\u2009CI 1.076 to 48.813, p&lt;0.05) and mild depression (aOR=3.808, 95%\u2009CI 1.652 to 8.776, p&lt;0.01). Postnatal impairment was linked to forceps delivery (aOR=1.874, 95%\u2009CI 1.007 to 3.483, p&lt;0.05), moderately high to high physical symptoms (moderately high: aOR=4.591, 95%\u2009CI 1.960 to 10.751, p&lt;0.01; high: aOR=13.277, 95%\u2009CI 5.501 to 32.073, p&lt;0.01), moderate anxiety (aOR=3.059, 95%\u2009CI 1.015 to 9.217, p&lt;0.05) and moderate to moderately severe depression (moderate: aOR=10.538, 95%\u2009CI 3.327 to 33.415, p&lt;0.01; moderately severe: aOR=23.453, 95%\u2009CI 1.383 to 398.218, p&lt;0.05). A dose-response relationship was observed between the severity of antenatal impairment and postpartum morbidities (all p&lt;0.001 for moderate and severe impairment).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Functional impairment is prevalent perinatally and associated interactively with maternal morbidities. Assessment of health-related functioning and the provision of targeted interventions are recommended to improve maternal health outcomes in the perinatal period and beyond.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2024-098624","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T10:50:14Z","timestamp":1766055014000},"page":"e098624","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Women\u2019s health-related functioning and its association with non-severe maternal morbidities during the perinatal period: an observational longitudinal study"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5442-2607","authenticated-orcid":false,"given":"Sulin","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Nursing, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanya","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiyi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Maternal, Child, and Adolescent Health, School of Public Health, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"},{"name":"Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangni","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Nursing, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"},{"name":"School of Nursing, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Nursing, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"},{"name":"Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Qian","sequence":"additional","affiliation":[{"name":"School of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1806-008X","authenticated-orcid":false,"given":"Chunyi","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Nursing, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China"},{"name":"School of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"2026010703474089000_15.12.e098624.1","unstructured":"WHO. 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