{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T06:20:17Z","timestamp":1791613217266,"version":"4.3.4"},"reference-count":47,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,6,17]]},"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to assess the pattern of disease and predictors of mortality among critically ill geriatric patients admitted to the intensive care unit at a teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A single-centre retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Medical-surgical intensive care unit of Tibebe Ghion Specialized Hospital, Bahir Dar, Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>We enrolled 296 critically ill patients (age 60+) admitted to the intensive care unit who stayed for more than 2\u2009hours. Those patients with missing or incomplete records were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Primary outcome measure<\/jats:title>\n                    <jats:p>The primary outcome of this study was the time to death within 30 days following intensive care unit admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In this cohort, the overall mortality rate of geriatric patients in the intensive care unit was found to be 42.9%. The incidence rate of mortality was 6.3 deaths per 100 person-days observation. Acute kidney injury (adjusted HR=2.36, 95% CI: 1.16, 3.68), coexisting diseases (adjusted HR=1.66, 95% CI: 1.13, 2.42), the presence of shock (adjusted HR=2.27, 95% CI: 1.66, 4.53) and mechanical ventilation (adjusted HR=1.82, 95% CI: 1.14, 2.89) were predictors of mortality in the intensive care unit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The mortality rate in the intensive care unit among geriatric patients was high. Predictors of mortality in this population of critically ill geriatric patients included acute kidney injury, the presence of shock, coexisting diseases and mechanical ventilation in the intensive care unit.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-099038","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T22:55:27Z","timestamp":1751410527000},"page":"e099038","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Pattern of disease and predictors of mortality among critically ill geriatric patients admitted to intensive care unit at a teaching hospital in Ethiopia: a retrospective cohort study"],"prefix":"10.1136","volume":"15","author":[{"given":"Sitotaw Tesfa","family":"Zegeye","sequence":"first","affiliation":[{"name":"Department of Anesthesia, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meseret Hulualem","family":"Nega","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simachew Amogne","family":"Debas","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mulat Mossie","family":"Derseh","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4495-3260","authenticated-orcid":false,"given":"Amanuel Sisay","family":"Endeshaw","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,7,1]]},"reference":[{"key":"2025121601344257000_15.7.e099038.1","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/960575","article-title":"Risk factors for hospital and long-term mortality of critically ill elderly patients admitted to an intensive care unit","volume":"2014","author":"Mukhopadhyay","year":"2014","journal-title":"Biomed Res Int"},{"key":"2025121601344257000_15.7.e099038.2","doi-asserted-by":"crossref","first-page":"789","DOI":"10.4103\/0972-5229.146312","article-title":"Do Intensive Care Unit treatment modalities predict mortality in geriatric patients: An observational study from an Indian Intensive Care Unit","volume":"18","author":"Sodhi","year":"2014","journal-title":"Indian J Crit Care Med"},{"key":"2025121601344257000_15.7.e099038.3","unstructured":"Nationen V . 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